Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
HCC1143 ABT-737
0.01
Bcl2/XL
Misc
 1.0024 -0.00353
HCC1143 ABT-737
0.031623
Bcl2/XL
Misc
 1.0016 -0.00138
HCC1143 ABT-737
0.1
Bcl2/XL
Misc
 1.0034 0.00545
HCC1143 ABT-737
0.31623
Bcl2/XL
Misc
 0.9505 0.00674
HCC1143 ABT-737
1.0
Bcl2/XL
Misc
 0.8032 0.01643
HCC1143 ABT-737
3.1623
Bcl2/XL
Misc
 0.6766 0.03455
HCC1143 ABT-737
10.0
Bcl2/XL
Misc
 0.3758 0.05382
HCC1143 Vorinostat
0.001
HDAC
Misc
 1.0391 -0.00523
HCC1143 Vorinostat
0.0031623
HDAC
Misc
 1.0569 0.00610
HCC1143 Vorinostat
0.01
HDAC
Misc
 0.9469 -0.00513
HCC1143 Vorinostat
0.031623
HDAC
Misc
 1.0284 -0.00141
HCC1143 Vorinostat
0.1
HDAC
Misc
 0.9283 -0.00041
HCC1143 Vorinostat
0.31623
HDAC
Misc
 0.9473 0.00358
HCC1143 Vorinostat
1.0
HDAC
Misc
 0.4229 0.09561
HCC1143 Vorinostat
3.1623
HDAC
Misc
 -0.0793 0.32859
HCC1143 Vorinostat
10.0
HDAC
Misc
 -0.2533 0.45717
HCC1143 Luminespib
0.0001
HSP90
Misc
 0.9419 -0.00109
HCC1143 Luminespib
0.00031623
HSP90
Misc
 0.9212 -0.00285
HCC1143 Luminespib
0.001
HSP90
Misc
 1.1185 0.00841
HCC1143 Luminespib
0.0031623
HSP90
Misc
 0.7065 0.03766
HCC1143 Luminespib
0.01
HSP90
Misc
 -0.1254 0.25970
HCC1143 Luminespib
0.031623
HSP90
Misc
 -0.1746 0.29615
HCC1143 Luminespib
0.1
HSP90
Misc
 -0.1795 0.29186
HCC1143 Luminespib
0.31623
HSP90
Misc
 -0.1869 0.31571
HCC1143 Luminespib
1.0
HSP90
Misc
 -0.1922 0.28739