Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)
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Cell | Small Molecule | Small Mol Concentration (uM) | Primary Target | Pathway | Mean Normalized Growth Rate Inhibition Value | Increased Fraction Dead |
---|---|---|---|---|---|---|
PDXHCI002 | Taxol | 0.0001 | Chemo | Chemotherapy | 0.8527 | 0.04314 |
PDXHCI002 | Taxol | 0.00031623 | Chemo | Chemotherapy | 1.0255 | 0.00492 |
PDXHCI002 | Taxol | 0.001 | Chemo | Chemotherapy | 0.9067 | 0.01437 |
PDXHCI002 | Taxol | 0.0031623 | Chemo | Chemotherapy | 0.2801 | 0.17121 |
PDXHCI002 | Taxol | 0.01 | Chemo | Chemotherapy | -0.4417 | 0.63589 |
PDXHCI002 | Taxol | 0.031623 | Chemo | Chemotherapy | -0.4012 | 0.62532 |
PDXHCI002 | Taxol | 0.1 | Chemo | Chemotherapy | -0.4489 | 0.64650 |
PDXHCI002 | Taxol | 0.31623 | Chemo | Chemotherapy | -0.4564 | 0.66642 |
PDXHCI002 | Taxol | 1.0 | Chemo | Chemotherapy | -0.5117 | 0.68548 |
PDXHCI002 | Topotecan | 0.0010833 | Topo I | Chemotherapy | 0.8887 | -0.01368 |
PDXHCI002 | Topotecan | 0.0033333 | Topo I | Chemotherapy | 0.7862 | -0.07478 |
PDXHCI002 | Topotecan | 0.01 | Topo I | Chemotherapy | 0.3231 | -0.04961 |
PDXHCI002 | Topotecan | 0.031667 | Topo I | Chemotherapy | -0.1215 | 0.10239 |
PDXHCI002 | Topotecan | 0.1 | Topo I | Chemotherapy | -0.1014 | -0.03893 |
PDXHCI002 | Topotecan | 0.31623 | Topo I | Chemotherapy | -0.3017 | 0.10015 |
PDXHCI002 | Topotecan | 1.0 | Topo I | Chemotherapy | -0.3239 | 0.16866 |
PDXHCI002 | Topotecan | 3.1623 | Topo I | Chemotherapy | -0.4674 | 0.32962 |
PDXHCI002 | Topotecan | 10.0 | Topo I | Chemotherapy | -0.7006 | 0.51721 |
PDXHCI002 | Etoposide | 0.0010833 | Topo II | Chemotherapy | 1.0798 | -0.04076 |
PDXHCI002 | Etoposide | 0.0033333 | Topo II | Chemotherapy | 0.9115 | -0.02699 |
PDXHCI002 | Etoposide | 0.01 | Topo II | Chemotherapy | 0.9938 | -0.02608 |
PDXHCI002 | Etoposide | 0.031667 | Topo II | Chemotherapy | 0.9100 | -0.05329 |
PDXHCI002 | Etoposide | 0.1 | Topo II | Chemotherapy | 0.6449 | -0.08531 |
PDXHCI002 | Etoposide | 0.31623 | Topo II | Chemotherapy | 0.3668 | -0.10135 |
PDXHCI002 | Etoposide | 1.0 | Topo II | Chemotherapy | -0.0637 | 0.05917 |