Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (viability/apoptosis dataset 1 of 2) - Dataset (ID:20272)

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Cell Small Molecule 1 Small Molecule 2 Small Mol 1 Concentration Small Mol 2 Concentration Small Mol Conc Unit Time Point Time Point Unit Replicate Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction
MZ7-mel Vemurafenib Dasatinib 0.316 0.000
uM
 72
hr
 2 2628 229 0.4824 0.4216 0.0871 0.0846
MZ7-mel Vemurafenib Dasatinib 0.316 0.000
uM
 72
hr
 3 2625 208 0.4861 0.4216 0.0792 0.0846
MZ7-mel Vemurafenib Dasatinib 0.316 0.316
uM
 72
hr
 1 1471 126 0.2705 0.3242 0.0857 0.0687
MZ7-mel Vemurafenib Dasatinib 0.316 0.316
uM
 72
hr
 2 1837 96 0.3501 0.3242 0.0523 0.0687
MZ7-mel Vemurafenib Dasatinib 0.316 0.316
uM
 72
hr
 3 1879 128 0.3521 0.3242 0.0681 0.0687
MZ7-mel Vemurafenib Dasatinib 0.316 1.000
uM
 72
hr
 1 2110 115 0.4012 0.3143 0.0545 0.0600
MZ7-mel Vemurafenib Dasatinib 0.316 1.000
uM
 72
hr
 2 1663 100 0.3143 0.3143 0.0601 0.0600
MZ7-mel Vemurafenib Dasatinib 0.316 1.000
uM
 72
hr
 3 1210 79 0.2274 0.3143 0.0653 0.0600
MZ7-mel Vemurafenib Dasatinib 0.316 3.160
uM
 72
hr
 1 1692 86 0.3230 0.2758 0.0508 0.0483
MZ7-mel Vemurafenib Dasatinib 0.316 3.160
uM
 72
hr
 2 1482 62 0.2856 0.2758 0.0418 0.0483
MZ7-mel Vemurafenib Dasatinib 0.316 3.160
uM
 72
hr
 3 1148 60 0.2188 0.2758 0.0523 0.0483
MZ7-mel Vemurafenib Dasatinib 1.000 0.000
uM
 72
hr
 1 1700 292 0.2831 0.3589 0.1718 0.1593
MZ7-mel Vemurafenib Dasatinib 1.000 0.000
uM
 72
hr
 2 2201 309 0.3805 0.3589 0.1404 0.1593
MZ7-mel Vemurafenib Dasatinib 1.000 0.000
uM
 72
hr
 3 2462 408 0.4131 0.3589 0.1657 0.1593
MZ7-mel Vemurafenib Dasatinib 1.000 0.316
uM
 72
hr
 1 1165 126 0.2089 0.2583 0.1082 0.1001
MZ7-mel Vemurafenib Dasatinib 1.000 0.316
uM
 72
hr
 2 1619 169 0.2916 0.2583 0.1044 0.1001
MZ7-mel Vemurafenib Dasatinib 1.000 0.316
uM
 72
hr
 3 1495 131 0.2743 0.2583 0.0876 0.1001
MZ7-mel Vemurafenib Dasatinib 1.000 1.000
uM
 72
hr
 1 1557 145 0.2840 0.2297 0.0931 0.0870
MZ7-mel Vemurafenib Dasatinib 1.000 1.000
uM
 72
hr
 2 1327 118 0.2431 0.2297 0.0889 0.0870
MZ7-mel Vemurafenib Dasatinib 1.000 1.000
uM
 72
hr
 3 875 69 0.1621 0.2297 0.0789 0.0870
MZ7-mel Vemurafenib Dasatinib 1.000 3.160
uM
 72
hr
 1 1146 101 0.2101 0.1839 0.0881 0.0837
MZ7-mel Vemurafenib Dasatinib 1.000 3.160
uM
 72
hr
 2 1029 86 0.1896 0.1839 0.0836 0.0837
MZ7-mel Vemurafenib Dasatinib 1.000 3.160
uM
 72
hr
 3 820 65 0.1518 0.1839 0.0793 0.0837
MZ7-mel Vemurafenib Dasatinib 3.160 0.000
uM
 72
hr
 1 1318 399 0.1848 0.2350 0.3027 0.3040
MZ7-mel Vemurafenib Dasatinib 3.160 0.000
uM
 72
hr
 2 1875 585 0.2594 0.2350 0.3120 0.3040