Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (viability/apoptosis dataset 1 of 2) - Dataset (ID:20272)

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Cell Small Molecule 1 Small Molecule 2 Small Mol 1 Concentration Small Mol 2 Concentration Small Mol Conc Unit Time Point Time Point Unit Replicate Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction
A-375 Vemurafenib Dasatinib 0.000 0.000
uM
 72
hr
 1 19971 929 0.9642 1.0000 0.0465 0.0504
A-375 Vemurafenib Dasatinib 0.000 0.000
uM
 72
hr
 2 20940 1098 1.0048 1.0000 0.0524 0.0504
A-375 Vemurafenib Dasatinib 0.000 0.000
uM
 72
hr
 3 21481 1121 1.0310 1.0000 0.0522 0.0504
A-375 Vemurafenib Dasatinib 0.000 0.316
uM
 72
hr
 1 5949 318 0.2851 0.2714 0.0535 0.0654
A-375 Vemurafenib Dasatinib 0.000 0.316
uM
 72
hr
 2 5334 374 0.2512 0.2714 0.0701 0.0654
A-375 Vemurafenib Dasatinib 0.000 0.316
uM
 72
hr
 3 5915 430 0.2777 0.2714 0.0727 0.0654
A-375 Vemurafenib Dasatinib 0.000 1.000
uM
 72
hr
 1 3016 167 0.1443 0.1539 0.0554 0.0544
A-375 Vemurafenib Dasatinib 0.000 1.000
uM
 72
hr
 2 3284 186 0.1569 0.1539 0.0566 0.0544
A-375 Vemurafenib Dasatinib 0.000 1.000
uM
 72
hr
 3 3339 171 0.1604 0.1539 0.0512 0.0544
A-375 Vemurafenib Dasatinib 0.000 3.160
uM
 72
hr
 1 4220 165 0.2053 0.1658 0.0391 0.0359
A-375 Vemurafenib Dasatinib 0.000 3.160
uM
 72
hr
 2 3068 107 0.1499 0.1658 0.0349 0.0359
A-375 Vemurafenib Dasatinib 0.000 3.160
uM
 72
hr
 3 2902 98 0.1420 0.1658 0.0338 0.0359
A-375 Vemurafenib Dasatinib 0.100 0.000
uM
 72
hr
 1 7790 111 0.3888 0.4180 0.0142 0.0173
A-375 Vemurafenib Dasatinib 0.100 0.000
uM
 72
hr
 2 8744 163 0.4345 0.4180 0.0186 0.0173
A-375 Vemurafenib Dasatinib 0.100 0.000
uM
 72
hr
 3 8666 164 0.4305 0.4180 0.0189 0.0173
A-375 Vemurafenib Dasatinib 0.100 0.316
uM
 72
hr
 1 3389 65 0.1683 0.1709 0.0192 0.0246
A-375 Vemurafenib Dasatinib 0.100 0.316
uM
 72
hr
 2 3458 92 0.1704 0.1709 0.0266 0.0246
A-375 Vemurafenib Dasatinib 0.100 0.316
uM
 72
hr
 3 3533 99 0.1739 0.1709 0.0280 0.0246
A-375 Vemurafenib Dasatinib 0.100 1.000
uM
 72
hr
 1 2680 77 0.1318 0.1200 0.0287 0.0313
A-375 Vemurafenib Dasatinib 0.100 1.000
uM
 72
hr
 2 2276 92 0.1106 0.1200 0.0404 0.0313
A-375 Vemurafenib Dasatinib 0.100 1.000
uM
 72
hr
 3 2383 59 0.1177 0.1200 0.0248 0.0313
A-375 Vemurafenib Dasatinib 0.100 3.160
uM
 72
hr
 1 2327 89 0.1133 0.0917 0.0382 0.0407
A-375 Vemurafenib Dasatinib 0.100 3.160
uM
 72
hr
 2 1659 68 0.0806 0.0917 0.0410 0.0407
A-375 Vemurafenib Dasatinib 0.100 3.160
uM
 72
hr
 3 1677 72 0.0813 0.0917 0.0429 0.0407
A-375 Vemurafenib Dasatinib 0.316 0.000
uM
 72
hr
 1 5034 110 0.2493 0.2652 0.0219 0.0225
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