Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (viability/apoptosis dataset 1 of 2) - Dataset (ID:20272)
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Cell | Small Molecule 1 | Small Molecule 2 | Small Mol 1 Concentration | Small Mol 2 Concentration | Small Mol Conc Unit | Time Point | Time Point Unit | Replicate | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction |
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MZ7-mel | Vemurafenib | Dasatinib | 0.000 | 0.000 | uM | 72 | hr | 1 | 4988 | 279 | 0.9470 | 1.0000 | 0.0559 | 0.0602 |
MZ7-mel | Vemurafenib | Dasatinib | 0.000 | 0.000 | uM | 72 | hr | 2 | 5344 | 345 | 1.0053 | 1.0000 | 0.0646 | 0.0602 |
MZ7-mel | Vemurafenib | Dasatinib | 0.000 | 0.000 | uM | 72 | hr | 3 | 5544 | 334 | 1.0477 | 1.0000 | 0.0602 | 0.0602 |
MZ7-mel | Vemurafenib | Dasatinib | 0.000 | 0.316 | uM | 72 | hr | 1 | 1225 | 69 | 0.2325 | 0.3530 | 0.0563 | 0.0606 |
MZ7-mel | Vemurafenib | Dasatinib | 0.000 | 0.316 | uM | 72 | hr | 2 | 1755 | 114 | 0.3300 | 0.3530 | 0.0650 | 0.0606 |
MZ7-mel | Vemurafenib | Dasatinib | 0.000 | 0.316 | uM | 72 | hr | 3 | 2628 | 159 | 0.4965 | 0.3530 | 0.0605 | 0.0606 |
MZ7-mel | Vemurafenib | Dasatinib | 0.000 | 1.000 | uM | 72 | hr | 1 | 1579 | 96 | 0.2982 | 0.2872 | 0.0608 | 0.0593 |
MZ7-mel | Vemurafenib | Dasatinib | 0.000 | 1.000 | uM | 72 | hr | 2 | 1439 | 86 | 0.2721 | 0.2872 | 0.0598 | 0.0593 |
MZ7-mel | Vemurafenib | Dasatinib | 0.000 | 1.000 | uM | 72 | hr | 3 | 1537 | 88 | 0.2914 | 0.2872 | 0.0573 | 0.0593 |
MZ7-mel | Vemurafenib | Dasatinib | 0.000 | 3.160 | uM | 72 | hr | 1 | 2499 | 153 | 0.4718 | 0.3781 | 0.0612 | 0.0626 |
MZ7-mel | Vemurafenib | Dasatinib | 0.000 | 3.160 | uM | 72 | hr | 2 | 2102 | 137 | 0.3952 | 0.3781 | 0.0652 | 0.0626 |
MZ7-mel | Vemurafenib | Dasatinib | 0.000 | 3.160 | uM | 72 | hr | 3 | 1416 | 87 | 0.2673 | 0.3781 | 0.0614 | 0.0626 |
MZ7-mel | Vemurafenib | Dasatinib | 0.100 | 0.000 | uM | 72 | hr | 1 | 2178 | 110 | 0.4159 | 0.5541 | 0.0505 | 0.0507 |
MZ7-mel | Vemurafenib | Dasatinib | 0.100 | 0.000 | uM | 72 | hr | 2 | 3222 | 169 | 0.6140 | 0.5541 | 0.0525 | 0.0507 |
MZ7-mel | Vemurafenib | Dasatinib | 0.100 | 0.000 | uM | 72 | hr | 3 | 3308 | 163 | 0.6325 | 0.5541 | 0.0493 | 0.0507 |
MZ7-mel | Vemurafenib | Dasatinib | 0.100 | 0.316 | uM | 72 | hr | 1 | 1886 | 144 | 0.3503 | 0.4729 | 0.0764 | 0.0666 |
MZ7-mel | Vemurafenib | Dasatinib | 0.100 | 0.316 | uM | 72 | hr | 2 | 2815 | 143 | 0.5373 | 0.4729 | 0.0508 | 0.0666 |
MZ7-mel | Vemurafenib | Dasatinib | 0.100 | 0.316 | uM | 72 | hr | 3 | 2847 | 207 | 0.5309 | 0.4729 | 0.0727 | 0.0666 |
MZ7-mel | Vemurafenib | Dasatinib | 0.100 | 1.000 | uM | 72 | hr | 1 | 2545 | 151 | 0.4814 | 0.4188 | 0.0593 | 0.0678 |
MZ7-mel | Vemurafenib | Dasatinib | 0.100 | 1.000 | uM | 72 | hr | 2 | 2481 | 164 | 0.4659 | 0.4188 | 0.0661 | 0.0678 |
MZ7-mel | Vemurafenib | Dasatinib | 0.100 | 1.000 | uM | 72 | hr | 3 | 1666 | 130 | 0.3089 | 0.4188 | 0.0780 | 0.0678 |
MZ7-mel | Vemurafenib | Dasatinib | 0.100 | 3.160 | uM | 72 | hr | 1 | 2547 | 163 | 0.4794 | 0.3555 | 0.0640 | 0.0539 |
MZ7-mel | Vemurafenib | Dasatinib | 0.100 | 3.160 | uM | 72 | hr | 2 | 1645 | 80 | 0.3147 | 0.3555 | 0.0486 | 0.0539 |
MZ7-mel | Vemurafenib | Dasatinib | 0.100 | 3.160 | uM | 72 | hr | 3 | 1425 | 70 | 0.2725 | 0.3555 | 0.0491 | 0.0539 |
MZ7-mel | Vemurafenib | Dasatinib | 0.316 | 0.000 | uM | 72 | hr | 1 | 1615 | 141 | 0.2964 | 0.4216 | 0.0873 | 0.0846 |