Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (viability/apoptosis dataset 1 of 2) - Dataset (ID:20272)

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Cell Small Molecule 1 Small Molecule 2 Small Mol 1 Concentration Small Mol 2 Concentration Small Mol Conc Unit Time Point Time Point Unit Replicate Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction
MMAC-SF Vemurafenib Dasatinib 3.160 0.000
uM
 72
hr
 3 664 293 0.2841 0.2946 0.4413 0.4049
MMAC-SF Vemurafenib Dasatinib 3.160 0.316
uM
 72
hr
 1 501 174 0.2504 0.2538 0.3473 0.3464
MMAC-SF Vemurafenib Dasatinib 3.160 0.316
uM
 72
hr
 2 465 150 0.2413 0.2538 0.3226 0.3464
MMAC-SF Vemurafenib Dasatinib 3.160 0.316
uM
 72
hr
 3 558 206 0.2696 0.2538 0.3692 0.3464
MMAC-SF Vemurafenib Dasatinib 3.160 1.000
uM
 72
hr
 1 840 273 0.4343 0.3712 0.3250 0.3204
MMAC-SF Vemurafenib Dasatinib 3.160 1.000
uM
 72
hr
 2 724 231 0.3776 0.3712 0.3191 0.3204
MMAC-SF Vemurafenib Dasatinib 3.160 1.000
uM
 72
hr
 3 577 183 0.3018 0.3712 0.3172 0.3204
MMAC-SF Vemurafenib Dasatinib 3.160 3.160
uM
 72
hr
 1 506 105 0.3071 0.2918 0.2075 0.1993
MMAC-SF Vemurafenib Dasatinib 3.160 3.160
uM
 72
hr
 2 471 92 0.2903 0.2918 0.1953 0.1993
MMAC-SF Vemurafenib Dasatinib 3.160 3.160
uM
 72
hr
 3 451 88 0.2780 0.2918 0.1951 0.1993
MMAC-SF Vemurafenib Defactinib 0.000 0.000
uM
 72
hr
 1 1665 69 0.9834 1.0000 0.0414 0.0422
MMAC-SF Vemurafenib Defactinib 0.000 0.000
uM
 72
hr
 2 1798 71 1.0641 1.0000 0.0395 0.0422
MMAC-SF Vemurafenib Defactinib 0.000 0.000
uM
 72
hr
 3 1620 74 0.9526 1.0000 0.0457 0.0422
MMAC-SF Vemurafenib Defactinib 0.000 0.316
uM
 72
hr
 1 1508 67 0.8879 1.1047 0.0444 0.0462
MMAC-SF Vemurafenib Defactinib 0.000 0.316
uM
 72
hr
 2 2014 89 1.1861 1.1047 0.0442 0.0462
MMAC-SF Vemurafenib Defactinib 0.000 0.316
uM
 72
hr
 3 2119 106 1.2403 1.1047 0.0500 0.0462
MMAC-SF Vemurafenib Defactinib 0.000 1.000
uM
 72
hr
 1 1089 33 0.6506 0.6001 0.0303 0.0364
MMAC-SF Vemurafenib Defactinib 0.000 1.000
uM
 72
hr
 2 1033 43 0.6100 0.6001 0.0416 0.0364
MMAC-SF Vemurafenib Defactinib 0.000 1.000
uM
 72
hr
 3 910 34 0.5397 0.6001 0.0374 0.0364
MMAC-SF Vemurafenib Defactinib 0.000 3.160
uM
 72
hr
 1 1027 40 0.6081 0.4909 0.0389 0.0363
MMAC-SF Vemurafenib Defactinib 0.000 3.160
uM
 72
hr
 2 837 30 0.4972 0.4909 0.0358 0.0363
MMAC-SF Vemurafenib Defactinib 0.000 3.160
uM
 72
hr
 3 617 21 0.3672 0.4909 0.0340 0.0363
MMAC-SF Vemurafenib Defactinib 0.100 0.000
uM
 72
hr
 1 1045 59 0.6075 0.6825 0.0565 0.0631
MMAC-SF Vemurafenib Defactinib 0.100 0.000
uM
 72
hr
 2 1285 81 0.7418 0.6825 0.0630 0.0631
MMAC-SF Vemurafenib Defactinib 0.100 0.000
uM
 72
hr
 3 1218 85 0.6981 0.6825 0.0698 0.0631