Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (viability/apoptosis dataset 1 of 2) - Dataset (ID:20272)

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Cell Small Molecule 1 Small Molecule 2 Small Mol 1 Concentration Small Mol 2 Concentration Small Mol Conc Unit Time Point Time Point Unit Replicate Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction
MMAC-SF Vemurafenib Dasatinib 0.316 0.000
uM
 72
hr
 2 859 151 0.5423 0.5371 0.1758 0.1786
MMAC-SF Vemurafenib Dasatinib 0.316 0.000
uM
 72
hr
 3 938 162 0.5943 0.5371 0.1727 0.1786
MMAC-SF Vemurafenib Dasatinib 0.316 0.316
uM
 72
hr
 1 782 102 0.5208 0.5813 0.1304 0.1242
MMAC-SF Vemurafenib Dasatinib 0.316 0.316
uM
 72
hr
 2 936 129 0.6181 0.5813 0.1378 0.1242
MMAC-SF Vemurafenib Dasatinib 0.316 0.316
uM
 72
hr
 3 882 92 0.6051 0.5813 0.1043 0.1242
MMAC-SF Vemurafenib Dasatinib 0.316 1.000
uM
 72
hr
 1 957 86 0.6671 0.5652 0.0899 0.0909
MMAC-SF Vemurafenib Dasatinib 0.316 1.000
uM
 72
hr
 2 742 58 0.5239 0.5652 0.0782 0.0909
MMAC-SF Vemurafenib Dasatinib 0.316 1.000
uM
 72
hr
 3 736 77 0.5047 0.5652 0.1046 0.0909
MMAC-SF Vemurafenib Dasatinib 0.316 3.160
uM
 72
hr
 1 976 91 0.6778 0.5614 0.0932 0.0959
MMAC-SF Vemurafenib Dasatinib 0.316 3.160
uM
 72
hr
 2 873 73 0.6127 0.5614 0.0836 0.0959
MMAC-SF Vemurafenib Dasatinib 0.316 3.160
uM
 72
hr
 3 578 64 0.3937 0.5614 0.1107 0.0959
MMAC-SF Vemurafenib Dasatinib 1.000 0.000
uM
 72
hr
 1 660 203 0.3500 0.3972 0.3076 0.3126
MMAC-SF Vemurafenib Dasatinib 1.000 0.000
uM
 72
hr
 2 743 233 0.3906 0.3972 0.3136 0.3126
MMAC-SF Vemurafenib Dasatinib 1.000 0.000
uM
 72
hr
 3 862 273 0.4511 0.3972 0.3167 0.3126
MMAC-SF Vemurafenib Dasatinib 1.000 0.316
uM
 72
hr
 1 616 148 0.3584 0.4029 0.2403 0.2375
MMAC-SF Vemurafenib Dasatinib 1.000 0.316
uM
 72
hr
 2 707 170 0.4113 0.4029 0.2405 0.2375
MMAC-SF Vemurafenib Dasatinib 1.000 0.316
uM
 72
hr
 3 746 173 0.4389 0.4029 0.2319 0.2375
MMAC-SF Vemurafenib Dasatinib 1.000 1.000
uM
 72
hr
 1 932 231 0.5369 0.4583 0.2479 0.2119
MMAC-SF Vemurafenib Dasatinib 1.000 1.000
uM
 72
hr
 2 769 142 0.4802 0.4583 0.1847 0.2119
MMAC-SF Vemurafenib Dasatinib 1.000 1.000
uM
 72
hr
 3 586 119 0.3577 0.4583 0.2031 0.2119
MMAC-SF Vemurafenib Dasatinib 1.000 3.160
uM
 72
hr
 1 898 135 0.5844 0.4386 0.1503 0.1472
MMAC-SF Vemurafenib Dasatinib 1.000 3.160
uM
 72
hr
 2 652 111 0.4143 0.4386 0.1702 0.1472
MMAC-SF Vemurafenib Dasatinib 1.000 3.160
uM
 72
hr
 3 471 57 0.3171 0.4386 0.1210 0.1472
MMAC-SF Vemurafenib Dasatinib 3.160 0.000
uM
 72
hr
 1 600 222 0.2895 0.2946 0.3700 0.4049
MMAC-SF Vemurafenib Dasatinib 3.160 0.000
uM
 72
hr
 2 679 274 0.3102 0.2946 0.4035 0.4049