Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (viability/apoptosis dataset 1 of 2) - Dataset (ID:20272)

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Cell Small Molecule 1 Small Molecule 2 Small Mol 1 Concentration Small Mol 2 Concentration Small Mol Conc Unit Time Point Time Point Unit Replicate Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction
MMAC-SF Vemurafenib Saracatinib 0.316 3.160
uM
 72
hr
 3 630 33 0.4763 0.6184 0.0524 0.0487
MMAC-SF Vemurafenib Saracatinib 1.000 0.000
uM
 72
hr
 1 855 222 0.5051 0.5481 0.2596 0.2669
MMAC-SF Vemurafenib Saracatinib 1.000 0.000
uM
 72
hr
 2 1046 285 0.6072 0.5481 0.2725 0.2669
MMAC-SF Vemurafenib Saracatinib 1.000 0.000
uM
 72
hr
 3 912 245 0.5322 0.5481 0.2686 0.2669
MMAC-SF Vemurafenib Saracatinib 1.000 0.316
uM
 72
hr
 1 774 111 0.5290 0.5769 0.1434 0.1727
MMAC-SF Vemurafenib Saracatinib 1.000 0.316
uM
 72
hr
 2 941 195 0.5952 0.5769 0.2072 0.1727
MMAC-SF Vemurafenib Saracatinib 1.000 0.316
uM
 72
hr
 3 913 153 0.6064 0.5769 0.1676 0.1727
MMAC-SF Vemurafenib Saracatinib 1.000 1.000
uM
 72
hr
 1 977 144 0.6646 0.5335 0.1474 0.1422
MMAC-SF Vemurafenib Saracatinib 1.000 1.000
uM
 72
hr
 2 820 119 0.5593 0.5335 0.1451 0.1422
MMAC-SF Vemurafenib Saracatinib 1.000 1.000
uM
 72
hr
 3 545 73 0.3766 0.5335 0.1339 0.1422
MMAC-SF Vemurafenib Saracatinib 1.000 3.160
uM
 72
hr
 1 823 140 0.5449 0.4894 0.1701 0.1367
MMAC-SF Vemurafenib Saracatinib 1.000 3.160
uM
 72
hr
 2 788 98 0.5505 0.4894 0.1244 0.1367
MMAC-SF Vemurafenib Saracatinib 1.000 3.160
uM
 72
hr
 3 528 61 0.3726 0.4894 0.1155 0.1367
MMAC-SF Vemurafenib Saracatinib 3.160 0.000
uM
 72
hr
 1 644 234 0.3271 0.3431 0.3634 0.3687
MMAC-SF Vemurafenib Saracatinib 3.160 0.000
uM
 72
hr
 2 642 245 0.3168 0.3431 0.3816 0.3687
MMAC-SF Vemurafenib Saracatinib 3.160 0.000
uM
 72
hr
 3 756 273 0.3854 0.3431 0.3611 0.3687
MMAC-SF Vemurafenib Saracatinib 3.160 0.316
uM
 72
hr
 1 486 158 0.2617 0.2955 0.3251 0.3065
MMAC-SF Vemurafenib Saracatinib 3.160 0.316
uM
 72
hr
 2 601 178 0.3375 0.2955 0.2962 0.3065
MMAC-SF Vemurafenib Saracatinib 3.160 0.316
uM
 72
hr
 3 513 153 0.2872 0.2955 0.2982 0.3065
MMAC-SF Vemurafenib Saracatinib 3.160 1.000
uM
 72
hr
 1 819 228 0.4715 0.3311 0.2784 0.2885
MMAC-SF Vemurafenib Saracatinib 3.160 1.000
uM
 72
hr
 2 587 183 0.3223 0.3311 0.3118 0.2885
MMAC-SF Vemurafenib Saracatinib 3.160 1.000
uM
 72
hr
 3 345 95 0.1995 0.3311 0.2754 0.2885
MMAC-SF Vemurafenib Saracatinib 3.160 3.160
uM
 72
hr
 1 545 138 0.3247 0.2628 0.2532 0.2739
MMAC-SF Vemurafenib Saracatinib 3.160 3.160
uM
 72
hr
 2 434 114 0.2553 0.2628 0.2627 0.2739
MMAC-SF Vemurafenib Saracatinib 3.160 3.160
uM
 72
hr
 3 376 115 0.2082 0.2628 0.3059 0.2739