Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (viability/apoptosis dataset 1 of 2) - Dataset (ID:20272)

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Cell Small Molecule 1 Small Molecule 2 Small Mol 1 Concentration Small Mol 2 Concentration Small Mol Conc Unit Time Point Time Point Unit Replicate Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction
MMAC-SF Vemurafenib Saracatinib 0.000 3.160
uM
 72
hr
 2 1146 49 0.8753 0.8059 0.0428 0.0432
MMAC-SF Vemurafenib Saracatinib 0.000 3.160
uM
 72
hr
 3 696 30 0.5314 0.8059 0.0431 0.0432
MMAC-SF Vemurafenib Saracatinib 0.100 0.000
uM
 72
hr
 1 981 39 0.7516 0.7976 0.0398 0.0486
MMAC-SF Vemurafenib Saracatinib 0.100 0.000
uM
 72
hr
 2 1126 71 0.8418 0.7976 0.0631 0.0486
MMAC-SF Vemurafenib Saracatinib 0.100 0.000
uM
 72
hr
 3 1047 45 0.7995 0.7976 0.0430 0.0486
MMAC-SF Vemurafenib Saracatinib 0.100 0.316
uM
 72
hr
 1 1049 35 0.8090 0.9306 0.0334 0.0304
MMAC-SF Vemurafenib Saracatinib 0.100 0.316
uM
 72
hr
 2 1347 40 1.0428 0.9306 0.0297 0.0304
MMAC-SF Vemurafenib Saracatinib 0.100 0.316
uM
 72
hr
 3 1212 34 0.9399 0.9306 0.0281 0.0304
MMAC-SF Vemurafenib Saracatinib 0.100 1.000
uM
 72
hr
 1 1024 31 0.7923 0.6896 0.0303 0.0319
MMAC-SF Vemurafenib Saracatinib 0.100 1.000
uM
 72
hr
 2 984 41 0.7524 0.6896 0.0417 0.0319
MMAC-SF Vemurafenib Saracatinib 0.100 1.000
uM
 72
hr
 3 673 16 0.5242 0.6896 0.0238 0.0319
MMAC-SF Vemurafenib Saracatinib 0.100 3.160
uM
 72
hr
 1 1082 34 0.8362 0.6941 0.0314 0.0337
MMAC-SF Vemurafenib Saracatinib 0.100 3.160
uM
 72
hr
 2 925 35 0.7101 0.6941 0.0378 0.0337
MMAC-SF Vemurafenib Saracatinib 0.100 3.160
uM
 72
hr
 3 694 22 0.5362 0.6941 0.0317 0.0337
MMAC-SF Vemurafenib Saracatinib 0.316 0.000
uM
 72
hr
 1 951 126 0.6582 0.7237 0.1325 0.1418
MMAC-SF Vemurafenib Saracatinib 0.316 0.000
uM
 72
hr
 2 1139 164 0.7779 0.7237 0.1440 0.1418
MMAC-SF Vemurafenib Saracatinib 0.316 0.000
uM
 72
hr
 3 1082 161 0.7348 0.7237 0.1488 0.1418
MMAC-SF Vemurafenib Saracatinib 0.316 0.316
uM
 72
hr
 1 984 71 0.7285 0.7894 0.0722 0.0654
MMAC-SF Vemurafenib Saracatinib 0.316 0.316
uM
 72
hr
 2 1093 67 0.8186 0.7894 0.0613 0.0654
MMAC-SF Vemurafenib Saracatinib 0.316 0.316
uM
 72
hr
 3 1098 69 0.8210 0.7894 0.0628 0.0654
MMAC-SF Vemurafenib Saracatinib 0.316 1.000
uM
 72
hr
 1 1184 65 0.8928 0.6590 0.0549 0.0562
MMAC-SF Vemurafenib Saracatinib 0.316 1.000
uM
 72
hr
 2 806 46 0.6064 0.6590 0.0571 0.0562
MMAC-SF Vemurafenib Saracatinib 0.316 1.000
uM
 72
hr
 3 635 36 0.4779 0.6590 0.0567 0.0562
MMAC-SF Vemurafenib Saracatinib 0.316 3.160
uM
 72
hr
 1 901 34 0.6918 0.6184 0.0377 0.0487
MMAC-SF Vemurafenib Saracatinib 0.316 3.160
uM
 72
hr
 2 912 51 0.6870 0.6184 0.0559 0.0487