Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (viability/apoptosis dataset 1 of 2) - Dataset (ID:20272)

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Cell Small Molecule 1 Small Molecule 2 Small Mol 1 Concentration Small Mol 2 Concentration Small Mol Conc Unit Time Point Time Point Unit Replicate Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction
WM-115 Vemurafenib Defactinib 0.100 0.316
uM
 72
hr
 1 3306 263 0.7274 0.7352 0.0796 0.0764
WM-115 Vemurafenib Defactinib 0.100 0.316
uM
 72
hr
 2 3380 271 0.7431 0.7352 0.0802 0.0764
WM-115 Vemurafenib Defactinib 0.100 0.316
uM
 72
hr
 3 3306 230 0.7352 0.7352 0.0696 0.0764
WM-115 Vemurafenib Defactinib 0.100 1.000
uM
 72
hr
 1 2973 253 0.6501 0.6192 0.0851 0.0777
WM-115 Vemurafenib Defactinib 0.100 1.000
uM
 72
hr
 2 2768 190 0.6162 0.6192 0.0686 0.0777
WM-115 Vemurafenib Defactinib 0.100 1.000
uM
 72
hr
 3 2686 213 0.5911 0.6192 0.0793 0.0777
WM-115 Vemurafenib Defactinib 0.100 3.160
uM
 72
hr
 1 2164 305 0.4443 0.4208 0.1409 0.1284
WM-115 Vemurafenib Defactinib 0.100 3.160
uM
 72
hr
 2 1905 223 0.4020 0.4208 0.1171 0.1284
WM-115 Vemurafenib Defactinib 0.100 3.160
uM
 72
hr
 3 1995 254 0.4161 0.4208 0.1273 0.1284
WM-115 Vemurafenib Defactinib 0.316 0.000
uM
 72
hr
 1 3047 246 0.6695 0.6656 0.0807 0.0837
WM-115 Vemurafenib Defactinib 0.316 0.000
uM
 72
hr
 2 3053 256 0.6686 0.6656 0.0839 0.0837
WM-115 Vemurafenib Defactinib 0.316 0.000
uM
 72
hr
 3 3017 261 0.6588 0.6656 0.0865 0.0837
WM-115 Vemurafenib Defactinib 0.316 0.316
uM
 72
hr
 1 2678 293 0.5701 0.5734 0.1094 0.1079
WM-115 Vemurafenib Defactinib 0.316 0.316
uM
 72
hr
 2 2706 306 0.5737 0.5734 0.1131 0.1079
WM-115 Vemurafenib Defactinib 0.316 0.316
uM
 72
hr
 3 2684 272 0.5765 0.5734 0.1013 0.1079
WM-115 Vemurafenib Defactinib 0.316 1.000
uM
 72
hr
 1 2505 277 0.5325 0.5180 0.1106 0.0997
WM-115 Vemurafenib Defactinib 0.316 1.000
uM
 72
hr
 2 2370 228 0.5120 0.5180 0.0962 0.0997
WM-115 Vemurafenib Defactinib 0.316 1.000
uM
 72
hr
 3 2349 217 0.5096 0.5180 0.0924 0.0997
WM-115 Vemurafenib Defactinib 0.316 3.160
uM
 72
hr
 1 1903 274 0.3894 0.3746 0.1440 0.1465
WM-115 Vemurafenib Defactinib 0.316 3.160
uM
 72
hr
 2 1877 261 0.3863 0.3746 0.1391 0.1465
WM-115 Vemurafenib Defactinib 0.316 3.160
uM
 72
hr
 3 1727 270 0.3483 0.3746 0.1563 0.1465
WM-115 Vemurafenib Defactinib 1.000 0.000
uM
 72
hr
 1 2704 422 0.5455 0.5412 0.1561 0.1460
WM-115 Vemurafenib Defactinib 1.000 0.000
uM
 72
hr
 2 2788 413 0.5677 0.5412 0.1481 0.1460
WM-115 Vemurafenib Defactinib 1.000 0.000
uM
 72
hr
 3 2465 330 0.5103 0.5412 0.1339 0.1460
WM-115 Vemurafenib Defactinib 1.000 0.316
uM
 72
hr
 1 2323 396 0.4606 0.4339 0.1705 0.1684