Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (viability/apoptosis dataset 1 of 2) - Dataset (ID:20272)

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Cell Small Molecule 1 Small Molecule 2 Small Mol 1 Concentration Small Mol 2 Concentration Small Mol Conc Unit Time Point Time Point Unit Replicate Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction
COLO 858 Vemurafenib JNK-IN-8 0.000 0.316
uM
 72
hr
 3 6666 937 0.9500 0.8682 0.1406 0.1425
COLO 858 Vemurafenib JNK-IN-8 0.000 1.000
uM
 72
hr
 1 4894 612 0.7101 0.7398 0.1251 0.1305
COLO 858 Vemurafenib JNK-IN-8 0.000 1.000
uM
 72
hr
 2 5229 702 0.7507 0.7398 0.1343 0.1305
COLO 858 Vemurafenib JNK-IN-8 0.000 1.000
uM
 72
hr
 3 5271 697 0.7585 0.7398 0.1322 0.1305
COLO 858 Vemurafenib JNK-IN-8 0.000 3.160
uM
 72
hr
 1 3782 731 0.5059 0.4677 0.1933 0.1974
COLO 858 Vemurafenib JNK-IN-8 0.000 3.160
uM
 72
hr
 2 3291 651 0.4378 0.4677 0.1978 0.1974
COLO 858 Vemurafenib JNK-IN-8 0.000 3.160
uM
 72
hr
 3 3469 698 0.4595 0.4677 0.2012 0.1974
COLO 858 Vemurafenib JNK-IN-8 0.100 0.000
uM
 72
hr
 1 3373 297 0.5101 0.4962 0.0881 0.0847
COLO 858 Vemurafenib JNK-IN-8 0.100 0.000
uM
 72
hr
 2 3208 272 0.4869 0.4962 0.0848 0.0847
COLO 858 Vemurafenib JNK-IN-8 0.100 0.000
uM
 72
hr
 3 3226 262 0.4915 0.4962 0.0812 0.0847
COLO 858 Vemurafenib JNK-IN-8 0.100 0.316
uM
 72
hr
 1 2621 401 0.3681 0.3841 0.1530 0.1420
COLO 858 Vemurafenib JNK-IN-8 0.100 0.316
uM
 72
hr
 2 2639 411 0.3695 0.3841 0.1557 0.1420
COLO 858 Vemurafenib JNK-IN-8 0.100 0.316
uM
 72
hr
 3 2833 332 0.4147 0.3841 0.1172 0.1420
COLO 858 Vemurafenib JNK-IN-8 0.100 1.000
uM
 72
hr
 1 2325 439 0.3128 0.3086 0.1888 0.1792
COLO 858 Vemurafenib JNK-IN-8 0.100 1.000
uM
 72
hr
 2 2322 411 0.3169 0.3086 0.1770 0.1792
COLO 858 Vemurafenib JNK-IN-8 0.100 1.000
uM
 72
hr
 3 2155 370 0.2960 0.3086 0.1717 0.1792
COLO 858 Vemurafenib JNK-IN-8 0.100 3.160
uM
 72
hr
 1 1834 545 0.2138 0.2001 0.2972 0.2904
COLO 858 Vemurafenib JNK-IN-8 0.100 3.160
uM
 72
hr
 2 1699 514 0.1965 0.2001 0.3025 0.2904
COLO 858 Vemurafenib JNK-IN-8 0.100 3.160
uM
 72
hr
 3 1573 427 0.1900 0.2001 0.2715 0.2904
COLO 858 Vemurafenib JNK-IN-8 0.316 0.000
uM
 72
hr
 1 2155 340 0.3010 0.2995 0.1578 0.1548
COLO 858 Vemurafenib JNK-IN-8 0.316 0.000
uM
 72
hr
 2 2104 329 0.2943 0.2995 0.1564 0.1548
COLO 858 Vemurafenib JNK-IN-8 0.316 0.000
uM
 72
hr
 3 2151 323 0.3031 0.2995 0.1502 0.1548
COLO 858 Vemurafenib JNK-IN-8 0.316 0.316
uM
 72
hr
 1 1562 486 0.1784 0.1736 0.3111 0.3188
COLO 858 Vemurafenib JNK-IN-8 0.316 0.316
uM
 72
hr
 2 1562 528 0.1715 0.1736 0.3380 0.3188
COLO 858 Vemurafenib JNK-IN-8 0.316 0.316
uM
 72
hr
 3 1488 457 0.1710 0.1736 0.3071 0.3188