Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (viability/apoptosis dataset 1 of 2) - Dataset (ID:20272)
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| Cell | Small Molecule 1 | Small Molecule 2 | Small Mol 1 Concentration | Small Mol 2 Concentration | Small Mol Conc Unit | Time Point | Time Point Unit | Replicate | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| COLO 858 | Vemurafenib | JNK-IN-8 | 0.316 | 1.000 | uM | 72 | hr | 1 | 1700 | 655 | 0.1733 | 0.1590 | 0.3853 | 0.3745 |
| COLO 858 | Vemurafenib | JNK-IN-8 | 0.316 | 1.000 | uM | 72 | hr | 2 | 1525 | 561 | 0.1599 | 0.1590 | 0.3679 | 0.3745 |
| COLO 858 | Vemurafenib | JNK-IN-8 | 0.316 | 1.000 | uM | 72 | hr | 3 | 1377 | 510 | 0.1438 | 0.1590 | 0.3704 | 0.3745 |
| COLO 858 | Vemurafenib | JNK-IN-8 | 0.316 | 3.160 | uM | 72 | hr | 1 | 1246 | 683 | 0.0934 | 0.0962 | 0.5482 | 0.5276 |
| COLO 858 | Vemurafenib | JNK-IN-8 | 0.316 | 3.160 | uM | 72 | hr | 2 | 1207 | 631 | 0.0955 | 0.0962 | 0.5228 | 0.5276 |
| COLO 858 | Vemurafenib | JNK-IN-8 | 0.316 | 3.160 | uM | 72 | hr | 3 | 1233 | 631 | 0.0998 | 0.0962 | 0.5118 | 0.5276 |
| COLO 858 | Vemurafenib | JNK-IN-8 | 1.000 | 0.000 | uM | 72 | hr | 1 | 1470 | 646 | 0.1366 | 0.1323 | 0.4395 | 0.4743 |
| COLO 858 | Vemurafenib | JNK-IN-8 | 1.000 | 0.000 | uM | 72 | hr | 2 | 1346 | 641 | 0.1169 | 0.1323 | 0.4762 | 0.4743 |
| COLO 858 | Vemurafenib | JNK-IN-8 | 1.000 | 0.000 | uM | 72 | hr | 3 | 1755 | 890 | 0.1434 | 0.1323 | 0.5071 | 0.4743 |
| COLO 858 | Vemurafenib | JNK-IN-8 | 1.000 | 0.316 | uM | 72 | hr | 1 | 1201 | 711 | 0.0813 | 0.0722 | 0.5920 | 0.5757 |
| COLO 858 | Vemurafenib | JNK-IN-8 | 1.000 | 0.316 | uM | 72 | hr | 2 | 832 | 414 | 0.0693 | 0.0722 | 0.4976 | 0.5757 |
| COLO 858 | Vemurafenib | JNK-IN-8 | 1.000 | 0.316 | uM | 72 | hr | 3 | 1101 | 702 | 0.0662 | 0.0722 | 0.6376 | 0.5757 |
| COLO 858 | Vemurafenib | JNK-IN-8 | 1.000 | 1.000 | uM | 72 | hr | 1 | 1349 | 929 | 0.0696 | 0.0651 | 0.6887 | 0.6828 |
| COLO 858 | Vemurafenib | JNK-IN-8 | 1.000 | 1.000 | uM | 72 | hr | 2 | 1201 | 807 | 0.0653 | 0.0651 | 0.6719 | 0.6828 |
| COLO 858 | Vemurafenib | JNK-IN-8 | 1.000 | 1.000 | uM | 72 | hr | 3 | 1163 | 800 | 0.0602 | 0.0651 | 0.6879 | 0.6828 |
| COLO 858 | Vemurafenib | JNK-IN-8 | 1.000 | 3.160 | uM | 72 | hr | 1 | 975 | 769 | 0.0342 | 0.0307 | 0.7887 | 0.7891 |
| COLO 858 | Vemurafenib | JNK-IN-8 | 1.000 | 3.160 | uM | 72 | hr | 2 | 839 | 656 | 0.0303 | 0.0307 | 0.7819 | 0.7891 |
| COLO 858 | Vemurafenib | JNK-IN-8 | 1.000 | 3.160 | uM | 72 | hr | 3 | 817 | 651 | 0.0275 | 0.0307 | 0.7968 | 0.7891 |
| COLO 858 | Vemurafenib | JNK-IN-8 | 3.160 | 0.000 | uM | 72 | hr | 1 | 1083 | 877 | 0.0342 | 0.0290 | 0.8098 | 0.8526 |
| COLO 858 | Vemurafenib | JNK-IN-8 | 3.160 | 0.000 | uM | 72 | hr | 2 | 1051 | 926 | 0.0207 | 0.0290 | 0.8811 | 0.8526 |
| COLO 858 | Vemurafenib | JNK-IN-8 | 3.160 | 0.000 | uM | 72 | hr | 3 | 1457 | 1263 | 0.0322 | 0.0290 | 0.8668 | 0.8526 |
| COLO 858 | Vemurafenib | JNK-IN-8 | 3.160 | 0.316 | uM | 72 | hr | 1 | 971 | 841 | 0.0216 | 0.0166 | 0.8661 | 0.8947 |
| COLO 858 | Vemurafenib | JNK-IN-8 | 3.160 | 0.316 | uM | 72 | hr | 2 | 911 | 825 | 0.0143 | 0.0166 | 0.9056 | 0.8947 |
| COLO 858 | Vemurafenib | JNK-IN-8 | 3.160 | 0.316 | uM | 72 | hr | 3 | 958 | 874 | 0.0139 | 0.0166 | 0.9123 | 0.8947 |
| COLO 858 | Vemurafenib | JNK-IN-8 | 3.160 | 1.000 | uM | 72 | hr | 1 | 1553 | 1428 | 0.0207 | 0.0156 | 0.9195 | 0.9257 |