Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (viability/apoptosis dataset 1 of 2) - Dataset (ID:20272)
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Cell | Small Molecule 1 | Small Molecule 2 | Small Mol 1 Concentration | Small Mol 2 Concentration | Small Mol Conc Unit | Time Point | Time Point Unit | Replicate | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction |
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COLO 858 | Vemurafenib | JNK-IN-8 | 3.160 | 1.000 | uM | 72 | hr | 2 | 1272 | 1188 | 0.0139 | 0.0156 | 0.9340 | 0.9257 |
COLO 858 | Vemurafenib | JNK-IN-8 | 3.160 | 1.000 | uM | 72 | hr | 3 | 954 | 881 | 0.0121 | 0.0156 | 0.9235 | 0.9257 |
COLO 858 | Vemurafenib | JNK-IN-8 | 3.160 | 3.160 | uM | 72 | hr | 1 | 955 | 894 | 0.0101 | 0.0089 | 0.9361 | 0.9423 |
COLO 858 | Vemurafenib | JNK-IN-8 | 3.160 | 3.160 | uM | 72 | hr | 2 | 759 | 722 | 0.0061 | 0.0089 | 0.9513 | 0.9423 |
COLO 858 | Vemurafenib | JNK-IN-8 | 3.160 | 3.160 | uM | 72 | hr | 3 | 1041 | 978 | 0.0104 | 0.0089 | 0.9395 | 0.9423 |
COLO 858 | Vemurafenib | PF562271 | 0.000 | 0.000 | uM | 72 | hr | 1 | 6915 | 1096 | 1.0494 | 1.0000 | 0.1585 | 0.1418 |
COLO 858 | Vemurafenib | PF562271 | 0.000 | 0.000 | uM | 72 | hr | 2 | 6456 | 909 | 1.0004 | 1.0000 | 0.1408 | 0.1418 |
COLO 858 | Vemurafenib | PF562271 | 0.000 | 0.000 | uM | 72 | hr | 3 | 6029 | 760 | 0.9502 | 1.0000 | 0.1261 | 0.1418 |
COLO 858 | Vemurafenib | PF562271 | 0.000 | 0.316 | uM | 72 | hr | 1 | 5564 | 919 | 0.8377 | 0.9265 | 0.1652 | 0.1634 |
COLO 858 | Vemurafenib | PF562271 | 0.000 | 0.316 | uM | 72 | hr | 2 | 6161 | 1037 | 0.9241 | 0.9265 | 0.1683 | 0.1634 |
COLO 858 | Vemurafenib | PF562271 | 0.000 | 0.316 | uM | 72 | hr | 3 | 6693 | 1049 | 1.0179 | 0.9265 | 0.1567 | 0.1634 |
COLO 858 | Vemurafenib | PF562271 | 0.000 | 1.000 | uM | 72 | hr | 1 | 2345 | 551 | 0.3235 | 0.3326 | 0.2350 | 0.2279 |
COLO 858 | Vemurafenib | PF562271 | 0.000 | 1.000 | uM | 72 | hr | 2 | 2246 | 541 | 0.3075 | 0.3326 | 0.2409 | 0.2279 |
COLO 858 | Vemurafenib | PF562271 | 0.000 | 1.000 | uM | 72 | hr | 3 | 2568 | 534 | 0.3668 | 0.3326 | 0.2079 | 0.2279 |
COLO 858 | Vemurafenib | PF562271 | 0.000 | 3.160 | uM | 72 | hr | 1 | 1125 | 559 | 0.1021 | 0.0736 | 0.4969 | 0.5166 |
COLO 858 | Vemurafenib | PF562271 | 0.000 | 3.160 | uM | 72 | hr | 2 | 788 | 414 | 0.0674 | 0.0736 | 0.5254 | 0.5166 |
COLO 858 | Vemurafenib | PF562271 | 0.000 | 3.160 | uM | 72 | hr | 3 | 601 | 317 | 0.0512 | 0.0736 | 0.5275 | 0.5166 |
COLO 858 | Vemurafenib | PF562271 | 0.100 | 0.000 | uM | 72 | hr | 1 | 2818 | 213 | 0.4698 | 0.4565 | 0.0756 | 0.0817 |
COLO 858 | Vemurafenib | PF562271 | 0.100 | 0.000 | uM | 72 | hr | 2 | 2708 | 257 | 0.4420 | 0.4565 | 0.0949 | 0.0817 |
COLO 858 | Vemurafenib | PF562271 | 0.100 | 0.000 | uM | 72 | hr | 3 | 2743 | 205 | 0.4577 | 0.4565 | 0.0747 | 0.0817 |
COLO 858 | Vemurafenib | PF562271 | 0.100 | 0.316 | uM | 72 | hr | 1 | 1909 | 224 | 0.3039 | 0.3380 | 0.1173 | 0.1281 |
COLO 858 | Vemurafenib | PF562271 | 0.100 | 0.316 | uM | 72 | hr | 2 | 2166 | 289 | 0.3385 | 0.3380 | 0.1334 | 0.1281 |
COLO 858 | Vemurafenib | PF562271 | 0.100 | 0.316 | uM | 72 | hr | 3 | 2379 | 318 | 0.3717 | 0.3380 | 0.1337 | 0.1281 |
COLO 858 | Vemurafenib | PF562271 | 0.100 | 1.000 | uM | 72 | hr | 1 | 1325 | 410 | 0.1650 | 0.1528 | 0.3094 | 0.2918 |
COLO 858 | Vemurafenib | PF562271 | 0.100 | 1.000 | uM | 72 | hr | 2 | 1127 | 326 | 0.1445 | 0.1528 | 0.2893 | 0.2918 |