Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (viability/apoptosis dataset 1 of 2) - Dataset (ID:20272)
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Cell | Small Molecule 1 | Small Molecule 2 | Small Mol 1 Concentration | Small Mol 2 Concentration | Small Mol Conc Unit | Time Point | Time Point Unit | Replicate | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction |
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MMAC-SF | Vemurafenib | Dasatinib | 0.000 | 0.000 | uM | 72 | hr | 1 | 1401 | 69 | 1.0202 | 1.0000 | 0.0493 | 0.0520 |
MMAC-SF | Vemurafenib | Dasatinib | 0.000 | 0.000 | uM | 72 | hr | 2 | 1380 | 79 | 0.9964 | 1.0000 | 0.0572 | 0.0520 |
MMAC-SF | Vemurafenib | Dasatinib | 0.000 | 0.000 | uM | 72 | hr | 3 | 1351 | 67 | 0.9834 | 1.0000 | 0.0496 | 0.0520 |
MMAC-SF | Vemurafenib | Dasatinib | 0.000 | 0.316 | uM | 72 | hr | 1 | 1253 | 76 | 0.9015 | 1.0853 | 0.0607 | 0.0619 |
MMAC-SF | Vemurafenib | Dasatinib | 0.000 | 0.316 | uM | 72 | hr | 2 | 1603 | 97 | 1.1534 | 1.0853 | 0.0605 | 0.0619 |
MMAC-SF | Vemurafenib | Dasatinib | 0.000 | 0.316 | uM | 72 | hr | 3 | 1676 | 108 | 1.2009 | 1.0853 | 0.0644 | 0.0619 |
MMAC-SF | Vemurafenib | Dasatinib | 0.000 | 1.000 | uM | 72 | hr | 1 | 1049 | 69 | 0.7506 | 0.6857 | 0.0658 | 0.0645 |
MMAC-SF | Vemurafenib | Dasatinib | 0.000 | 1.000 | uM | 72 | hr | 2 | 1045 | 58 | 0.7559 | 0.6857 | 0.0555 | 0.0645 |
MMAC-SF | Vemurafenib | Dasatinib | 0.000 | 1.000 | uM | 72 | hr | 3 | 775 | 56 | 0.5507 | 0.6857 | 0.0723 | 0.0645 |
MMAC-SF | Vemurafenib | Dasatinib | 0.000 | 3.160 | uM | 72 | hr | 1 | 1338 | 86 | 0.9589 | 0.7322 | 0.0643 | 0.0524 |
MMAC-SF | Vemurafenib | Dasatinib | 0.000 | 3.160 | uM | 72 | hr | 2 | 939 | 30 | 0.6962 | 0.7322 | 0.0319 | 0.0524 |
MMAC-SF | Vemurafenib | Dasatinib | 0.000 | 3.160 | uM | 72 | hr | 3 | 753 | 46 | 0.5415 | 0.7322 | 0.0611 | 0.0524 |
MMAC-SF | Vemurafenib | Dasatinib | 0.100 | 0.000 | uM | 72 | hr | 1 | 885 | 43 | 0.6449 | 0.7202 | 0.0486 | 0.0513 |
MMAC-SF | Vemurafenib | Dasatinib | 0.100 | 0.000 | uM | 72 | hr | 2 | 1049 | 58 | 0.7590 | 0.7202 | 0.0553 | 0.0513 |
MMAC-SF | Vemurafenib | Dasatinib | 0.100 | 0.000 | uM | 72 | hr | 3 | 1040 | 52 | 0.7567 | 0.7202 | 0.0500 | 0.0513 |
MMAC-SF | Vemurafenib | Dasatinib | 0.100 | 0.316 | uM | 72 | hr | 1 | 915 | 46 | 0.6656 | 0.7554 | 0.0503 | 0.0454 |
MMAC-SF | Vemurafenib | Dasatinib | 0.100 | 0.316 | uM | 72 | hr | 2 | 1106 | 50 | 0.8088 | 0.7554 | 0.0452 | 0.0454 |
MMAC-SF | Vemurafenib | Dasatinib | 0.100 | 0.316 | uM | 72 | hr | 3 | 1078 | 44 | 0.7919 | 0.7554 | 0.0408 | 0.0454 |
MMAC-SF | Vemurafenib | Dasatinib | 0.100 | 1.000 | uM | 72 | hr | 1 | 959 | 43 | 0.7016 | 0.6038 | 0.0448 | 0.0460 |
MMAC-SF | Vemurafenib | Dasatinib | 0.100 | 1.000 | uM | 72 | hr | 2 | 867 | 41 | 0.6326 | 0.6038 | 0.0473 | 0.0460 |
MMAC-SF | Vemurafenib | Dasatinib | 0.100 | 1.000 | uM | 72 | hr | 3 | 653 | 30 | 0.4772 | 0.6038 | 0.0459 | 0.0460 |
MMAC-SF | Vemurafenib | Dasatinib | 0.100 | 3.160 | uM | 72 | hr | 1 | 1039 | 59 | 0.7506 | 0.6145 | 0.0568 | 0.0615 |
MMAC-SF | Vemurafenib | Dasatinib | 0.100 | 3.160 | uM | 72 | hr | 2 | 896 | 69 | 0.6334 | 0.6145 | 0.0770 | 0.0615 |
MMAC-SF | Vemurafenib | Dasatinib | 0.100 | 3.160 | uM | 72 | hr | 3 | 632 | 32 | 0.4595 | 0.6145 | 0.0506 | 0.0615 |
MMAC-SF | Vemurafenib | Dasatinib | 0.316 | 0.000 | uM | 72 | hr | 1 | 763 | 143 | 0.4749 | 0.5371 | 0.1874 | 0.1786 |