Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (viability/apoptosis dataset 1 of 2) - Dataset (ID:20272)

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Cell Small Molecule 1 Small Molecule 2 Small Mol 1 Concentration Small Mol 2 Concentration Small Mol Conc Unit Time Point Time Point Unit Replicate Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction
MMAC-SF Vemurafenib Dasatinib 0.000 0.000
uM
72
hr
1 1401 69 1.0202 1.0000 0.0493 0.0520
MMAC-SF Vemurafenib Dasatinib 0.000 0.000
uM
72
hr
2 1380 79 0.9964 1.0000 0.0572 0.0520
MMAC-SF Vemurafenib Dasatinib 0.000 0.000
uM
72
hr
3 1351 67 0.9834 1.0000 0.0496 0.0520
MMAC-SF Vemurafenib Dasatinib 0.000 0.316
uM
72
hr
1 1253 76 0.9015 1.0853 0.0607 0.0619
MMAC-SF Vemurafenib Dasatinib 0.000 0.316
uM
72
hr
2 1603 97 1.1534 1.0853 0.0605 0.0619
MMAC-SF Vemurafenib Dasatinib 0.000 0.316
uM
72
hr
3 1676 108 1.2009 1.0853 0.0644 0.0619
MMAC-SF Vemurafenib Dasatinib 0.000 1.000
uM
72
hr
1 1049 69 0.7506 0.6857 0.0658 0.0645
MMAC-SF Vemurafenib Dasatinib 0.000 1.000
uM
72
hr
2 1045 58 0.7559 0.6857 0.0555 0.0645
MMAC-SF Vemurafenib Dasatinib 0.000 1.000
uM
72
hr
3 775 56 0.5507 0.6857 0.0723 0.0645
MMAC-SF Vemurafenib Dasatinib 0.000 3.160
uM
72
hr
1 1338 86 0.9589 0.7322 0.0643 0.0524
MMAC-SF Vemurafenib Dasatinib 0.000 3.160
uM
72
hr
2 939 30 0.6962 0.7322 0.0319 0.0524
MMAC-SF Vemurafenib Dasatinib 0.000 3.160
uM
72
hr
3 753 46 0.5415 0.7322 0.0611 0.0524
MMAC-SF Vemurafenib Dasatinib 0.100 0.000
uM
72
hr
1 885 43 0.6449 0.7202 0.0486 0.0513
MMAC-SF Vemurafenib Dasatinib 0.100 0.000
uM
72
hr
2 1049 58 0.7590 0.7202 0.0553 0.0513
MMAC-SF Vemurafenib Dasatinib 0.100 0.000
uM
72
hr
3 1040 52 0.7567 0.7202 0.0500 0.0513
MMAC-SF Vemurafenib Dasatinib 0.100 0.316
uM
72
hr
1 915 46 0.6656 0.7554 0.0503 0.0454
MMAC-SF Vemurafenib Dasatinib 0.100 0.316
uM
72
hr
2 1106 50 0.8088 0.7554 0.0452 0.0454
MMAC-SF Vemurafenib Dasatinib 0.100 0.316
uM
72
hr
3 1078 44 0.7919 0.7554 0.0408 0.0454
MMAC-SF Vemurafenib Dasatinib 0.100 1.000
uM
72
hr
1 959 43 0.7016 0.6038 0.0448 0.0460
MMAC-SF Vemurafenib Dasatinib 0.100 1.000
uM
72
hr
2 867 41 0.6326 0.6038 0.0473 0.0460
MMAC-SF Vemurafenib Dasatinib 0.100 1.000
uM
72
hr
3 653 30 0.4772 0.6038 0.0459 0.0460
MMAC-SF Vemurafenib Dasatinib 0.100 3.160
uM
72
hr
1 1039 59 0.7506 0.6145 0.0568 0.0615
MMAC-SF Vemurafenib Dasatinib 0.100 3.160
uM
72
hr
2 896 69 0.6334 0.6145 0.0770 0.0615
MMAC-SF Vemurafenib Dasatinib 0.100 3.160
uM
72
hr
3 632 32 0.4595 0.6145 0.0506 0.0615
MMAC-SF Vemurafenib Dasatinib 0.316 0.000
uM
72
hr
1 763 143 0.4749 0.5371 0.1874 0.1786