Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (viability/apoptosis dataset 1 of 2) - Dataset (ID:20272)
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| Cell | Small Molecule 1 | Small Molecule 2 | Small Mol 1 Concentration | Small Mol 2 Concentration | Small Mol Conc Unit | Time Point | Time Point Unit | Replicate | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| WM-115 | Vemurafenib | Saracatinib | 0.316 | 3.160 | uM | 72 | hr | 3 | 2084 | 267 | 0.4725 | 0.4743 | 0.1281 | 0.1338 |
| WM-115 | Vemurafenib | Saracatinib | 1.000 | 0.000 | uM | 72 | hr | 1 | 2343 | 340 | 0.5208 | 0.5494 | 0.1451 | 0.1416 |
| WM-115 | Vemurafenib | Saracatinib | 1.000 | 0.000 | uM | 72 | hr | 2 | 2517 | 352 | 0.5630 | 0.5494 | 0.1398 | 0.1416 |
| WM-115 | Vemurafenib | Saracatinib | 1.000 | 0.000 | uM | 72 | hr | 3 | 2523 | 353 | 0.5643 | 0.5494 | 0.1399 | 0.1416 |
| WM-115 | Vemurafenib | Saracatinib | 1.000 | 0.316 | uM | 72 | hr | 1 | 2225 | 275 | 0.5071 | 0.5099 | 0.1236 | 0.1408 |
| WM-115 | Vemurafenib | Saracatinib | 1.000 | 0.316 | uM | 72 | hr | 2 | 2260 | 327 | 0.5026 | 0.5099 | 0.1447 | 0.1408 |
| WM-115 | Vemurafenib | Saracatinib | 1.000 | 0.316 | uM | 72 | hr | 3 | 2364 | 364 | 0.5201 | 0.5099 | 0.1540 | 0.1408 |
| WM-115 | Vemurafenib | Saracatinib | 1.000 | 1.000 | uM | 72 | hr | 1 | 1865 | 281 | 0.4119 | 0.4022 | 0.1507 | 0.1546 |
| WM-115 | Vemurafenib | Saracatinib | 1.000 | 1.000 | uM | 72 | hr | 2 | 1924 | 287 | 0.4257 | 0.4022 | 0.1492 | 0.1546 |
| WM-115 | Vemurafenib | Saracatinib | 1.000 | 1.000 | uM | 72 | hr | 3 | 1697 | 278 | 0.3690 | 0.4022 | 0.1638 | 0.1546 |
| WM-115 | Vemurafenib | Saracatinib | 1.000 | 3.160 | uM | 72 | hr | 1 | 1760 | 362 | 0.3635 | 0.3608 | 0.2057 | 0.1852 |
| WM-115 | Vemurafenib | Saracatinib | 1.000 | 3.160 | uM | 72 | hr | 2 | 1740 | 336 | 0.3651 | 0.3608 | 0.1931 | 0.1852 |
| WM-115 | Vemurafenib | Saracatinib | 1.000 | 3.160 | uM | 72 | hr | 3 | 1614 | 253 | 0.3539 | 0.3608 | 0.1568 | 0.1852 |
| WM-115 | Vemurafenib | Saracatinib | 3.160 | 0.000 | uM | 72 | hr | 1 | 1883 | 435 | 0.3765 | 0.3772 | 0.2310 | 0.2307 |
| WM-115 | Vemurafenib | Saracatinib | 3.160 | 0.000 | uM | 72 | hr | 2 | 1886 | 416 | 0.3822 | 0.3772 | 0.2206 | 0.2307 |
| WM-115 | Vemurafenib | Saracatinib | 3.160 | 0.000 | uM | 72 | hr | 3 | 1888 | 454 | 0.3729 | 0.3772 | 0.2405 | 0.2307 |
| WM-115 | Vemurafenib | Saracatinib | 3.160 | 0.316 | uM | 72 | hr | 1 | 1784 | 448 | 0.3474 | 0.3501 | 0.2511 | 0.2561 |
| WM-115 | Vemurafenib | Saracatinib | 3.160 | 0.316 | uM | 72 | hr | 2 | 1903 | 484 | 0.3690 | 0.3501 | 0.2543 | 0.2561 |
| WM-115 | Vemurafenib | Saracatinib | 3.160 | 0.316 | uM | 72 | hr | 3 | 1742 | 458 | 0.3339 | 0.3501 | 0.2629 | 0.2561 |
| WM-115 | Vemurafenib | Saracatinib | 3.160 | 1.000 | uM | 72 | hr | 1 | 1476 | 418 | 0.2751 | 0.2647 | 0.2832 | 0.2681 |
| WM-115 | Vemurafenib | Saracatinib | 3.160 | 1.000 | uM | 72 | hr | 2 | 1452 | 383 | 0.2780 | 0.2647 | 0.2638 | 0.2681 |
| WM-115 | Vemurafenib | Saracatinib | 3.160 | 1.000 | uM | 72 | hr | 3 | 1248 | 321 | 0.2411 | 0.2647 | 0.2572 | 0.2681 |
| WM-115 | Vemurafenib | Saracatinib | 3.160 | 3.160 | uM | 72 | hr | 1 | 1354 | 459 | 0.2327 | 0.2251 | 0.3390 | 0.3147 |
| WM-115 | Vemurafenib | Saracatinib | 3.160 | 3.160 | uM | 72 | hr | 2 | 1196 | 350 | 0.2200 | 0.2251 | 0.2926 | 0.3147 |
| WM-115 | Vemurafenib | Saracatinib | 3.160 | 3.160 | uM | 72 | hr | 3 | 1245 | 389 | 0.2226 | 0.2251 | 0.3124 | 0.3147 |