Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (viability/apoptosis dataset 1 of 2) - Dataset (ID:20272)
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| Cell | Small Molecule 1 | Small Molecule 2 | Small Mol 1 Concentration | Small Mol 2 Concentration | Small Mol Conc Unit | Time Point | Time Point Unit | Replicate | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| WM-115 | Vemurafenib | Dasatinib | 0.316 | 0.000 | uM | 72 | hr | 2 | 3197 | 306 | 0.7217 | 0.7092 | 0.0957 | 0.0818 |
| WM-115 | Vemurafenib | Dasatinib | 0.316 | 0.000 | uM | 72 | hr | 3 | 3086 | 246 | 0.7089 | 0.7092 | 0.0797 | 0.0818 |
| WM-115 | Vemurafenib | Dasatinib | 0.316 | 0.316 | uM | 72 | hr | 1 | 1897 | 707 | 0.2971 | 0.2711 | 0.3727 | 0.3806 |
| WM-115 | Vemurafenib | Dasatinib | 0.316 | 0.316 | uM | 72 | hr | 2 | 1699 | 642 | 0.2639 | 0.2711 | 0.3779 | 0.3806 |
| WM-115 | Vemurafenib | Dasatinib | 0.316 | 0.316 | uM | 72 | hr | 3 | 1661 | 650 | 0.2524 | 0.2711 | 0.3913 | 0.3806 |
| WM-115 | Vemurafenib | Dasatinib | 0.316 | 1.000 | uM | 72 | hr | 1 | 1897 | 677 | 0.3045 | 0.2911 | 0.3569 | 0.3460 |
| WM-115 | Vemurafenib | Dasatinib | 0.316 | 1.000 | uM | 72 | hr | 2 | 1738 | 607 | 0.2823 | 0.2911 | 0.3493 | 0.3460 |
| WM-115 | Vemurafenib | Dasatinib | 0.316 | 1.000 | uM | 72 | hr | 3 | 1717 | 570 | 0.2863 | 0.2911 | 0.3320 | 0.3460 |
| WM-115 | Vemurafenib | Dasatinib | 0.316 | 3.160 | uM | 72 | hr | 1 | 1732 | 601 | 0.2823 | 0.2889 | 0.3470 | 0.3083 |
| WM-115 | Vemurafenib | Dasatinib | 0.316 | 3.160 | uM | 72 | hr | 2 | 1692 | 540 | 0.2876 | 0.2889 | 0.3191 | 0.3083 |
| WM-115 | Vemurafenib | Dasatinib | 0.316 | 3.160 | uM | 72 | hr | 3 | 1604 | 415 | 0.2968 | 0.2889 | 0.2587 | 0.3083 |
| WM-115 | Vemurafenib | Dasatinib | 1.000 | 0.000 | uM | 72 | hr | 1 | 2605 | 357 | 0.5612 | 0.5745 | 0.1370 | 0.1322 |
| WM-115 | Vemurafenib | Dasatinib | 1.000 | 0.000 | uM | 72 | hr | 2 | 2677 | 361 | 0.5781 | 0.5745 | 0.1349 | 0.1322 |
| WM-115 | Vemurafenib | Dasatinib | 1.000 | 0.000 | uM | 72 | hr | 3 | 2673 | 333 | 0.5841 | 0.5745 | 0.1246 | 0.1322 |
| WM-115 | Vemurafenib | Dasatinib | 1.000 | 0.316 | uM | 72 | hr | 1 | 1576 | 666 | 0.2272 | 0.2193 | 0.4226 | 0.3870 |
| WM-115 | Vemurafenib | Dasatinib | 1.000 | 0.316 | uM | 72 | hr | 2 | 1348 | 506 | 0.2102 | 0.2193 | 0.3754 | 0.3870 |
| WM-115 | Vemurafenib | Dasatinib | 1.000 | 0.316 | uM | 72 | hr | 3 | 1388 | 504 | 0.2207 | 0.2193 | 0.3631 | 0.3870 |
| WM-115 | Vemurafenib | Dasatinib | 1.000 | 1.000 | uM | 72 | hr | 1 | 1517 | 589 | 0.2317 | 0.2248 | 0.3883 | 0.3610 |
| WM-115 | Vemurafenib | Dasatinib | 1.000 | 1.000 | uM | 72 | hr | 2 | 1378 | 473 | 0.2259 | 0.2248 | 0.3433 | 0.3610 |
| WM-115 | Vemurafenib | Dasatinib | 1.000 | 1.000 | uM | 72 | hr | 3 | 1340 | 471 | 0.2169 | 0.2248 | 0.3515 | 0.3610 |
| WM-115 | Vemurafenib | Dasatinib | 1.000 | 3.160 | uM | 72 | hr | 1 | 1156 | 371 | 0.1960 | 0.2060 | 0.3209 | 0.3157 |
| WM-115 | Vemurafenib | Dasatinib | 1.000 | 3.160 | uM | 72 | hr | 2 | 1210 | 394 | 0.2037 | 0.2060 | 0.3256 | 0.3157 |
| WM-115 | Vemurafenib | Dasatinib | 1.000 | 3.160 | uM | 72 | hr | 3 | 1251 | 376 | 0.2184 | 0.2060 | 0.3006 | 0.3157 |
| WM-115 | Vemurafenib | Dasatinib | 3.160 | 0.000 | uM | 72 | hr | 1 | 2247 | 458 | 0.4466 | 0.4161 | 0.2038 | 0.2078 |
| WM-115 | Vemurafenib | Dasatinib | 3.160 | 0.000 | uM | 72 | hr | 2 | 2023 | 423 | 0.3994 | 0.4161 | 0.2091 | 0.2078 |