Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (viability/apoptosis dataset 1 of 2) - Dataset (ID:20272)

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Cell Small Molecule 1 Small Molecule 2 Small Mol 1 Concentration Small Mol 2 Concentration Small Mol Conc Unit Time Point Time Point Unit Replicate Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction
WM-115 Vemurafenib Saracatinib 0.000 3.160
uM
 72
hr
 2 3055 210 0.7398 0.6962 0.0687 0.0731
WM-115 Vemurafenib Saracatinib 0.000 3.160
uM
 72
hr
 3 2606 184 0.6298 0.6962 0.0706 0.0731
WM-115 Vemurafenib Saracatinib 0.100 0.000
uM
 72
hr
 1 3407 205 0.8326 0.8606 0.0602 0.0629
WM-115 Vemurafenib Saracatinib 0.100 0.000
uM
 72
hr
 2 3631 226 0.8854 0.8606 0.0622 0.0629
WM-115 Vemurafenib Saracatinib 0.100 0.000
uM
 72
hr
 3 3558 236 0.8638 0.8606 0.0663 0.0629
WM-115 Vemurafenib Saracatinib 0.100 0.316
uM
 72
hr
 1 2904 195 0.7044 0.7665 0.0671 0.0659
WM-115 Vemurafenib Saracatinib 0.100 0.316
uM
 72
hr
 2 3246 205 0.7908 0.7665 0.0632 0.0659
WM-115 Vemurafenib Saracatinib 0.100 0.316
uM
 72
hr
 3 3316 223 0.8043 0.7665 0.0672 0.0659
WM-115 Vemurafenib Saracatinib 0.100 1.000
uM
 72
hr
 1 2757 194 0.6665 0.6617 0.0704 0.0684
WM-115 Vemurafenib Saracatinib 0.100 1.000
uM
 72
hr
 2 2651 173 0.6444 0.6617 0.0653 0.0684
WM-115 Vemurafenib Saracatinib 0.100 1.000
uM
 72
hr
 3 2787 194 0.6743 0.6617 0.0696 0.0684
WM-115 Vemurafenib Saracatinib 0.100 3.160
uM
 72
hr
 1 2506 243 0.5885 0.5553 0.0970 0.0985
WM-115 Vemurafenib Saracatinib 0.100 3.160
uM
 72
hr
 2 2322 246 0.5398 0.5553 0.1059 0.0985
WM-115 Vemurafenib Saracatinib 0.100 3.160
uM
 72
hr
 3 2278 211 0.5375 0.5553 0.0926 0.0985
WM-115 Vemurafenib Saracatinib 0.316 0.000
uM
 72
hr
 1 3037 214 0.7341 0.7069 0.0705 0.0799
WM-115 Vemurafenib Saracatinib 0.316 0.000
uM
 72
hr
 2 2971 248 0.7081 0.7069 0.0835 0.0799
WM-115 Vemurafenib Saracatinib 0.316 0.000
uM
 72
hr
 3 2855 245 0.6787 0.7069 0.0858 0.0799
WM-115 Vemurafenib Saracatinib 0.316 0.316
uM
 72
hr
 1 2669 252 0.6285 0.6528 0.0944 0.0956
WM-115 Vemurafenib Saracatinib 0.316 0.316
uM
 72
hr
 2 2791 271 0.6553 0.6528 0.0971 0.0956
WM-115 Vemurafenib Saracatinib 0.316 0.316
uM
 72
hr
 3 2867 273 0.6745 0.6528 0.0952 0.0956
WM-115 Vemurafenib Saracatinib 0.316 1.000
uM
 72
hr
 1 2214 217 0.5193 0.4954 0.0980 0.0888
WM-115 Vemurafenib Saracatinib 0.316 1.000
uM
 72
hr
 2 2106 168 0.5039 0.4954 0.0798 0.0888
WM-115 Vemurafenib Saracatinib 0.316 1.000
uM
 72
hr
 3 1953 173 0.4629 0.4954 0.0886 0.0888
WM-115 Vemurafenib Saracatinib 0.316 3.160
uM
 72
hr
 1 2173 305 0.4857 0.4743 0.1404 0.1338
WM-115 Vemurafenib Saracatinib 0.316 3.160
uM
 72
hr
 2 2061 274 0.4647 0.4743 0.1329 0.1338