Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (viability/apoptosis dataset 1 of 2) - Dataset (ID:20272)

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Cell Small Molecule 1 Small Molecule 2 Small Mol 1 Concentration Small Mol 2 Concentration Small Mol Conc Unit Time Point Time Point Unit Replicate Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction
MZ7-mel Vemurafenib Saracatinib 0.000 3.160
uM
 72
hr
 2 3224 245 0.9716 0.9734 0.0760 0.0805
MZ7-mel Vemurafenib Saracatinib 0.000 3.160
uM
 72
hr
 3 1605 149 0.4749 0.9734 0.0928 0.0805
MZ7-mel Vemurafenib Saracatinib 0.100 0.000
uM
 72
hr
 1 1917 95 0.5943 0.7294 0.0496 0.0484
MZ7-mel Vemurafenib Saracatinib 0.100 0.000
uM
 72
hr
 2 2418 122 0.7489 0.7294 0.0505 0.0484
MZ7-mel Vemurafenib Saracatinib 0.100 0.000
uM
 72
hr
 3 2714 123 0.8451 0.7294 0.0453 0.0484
MZ7-mel Vemurafenib Saracatinib 0.100 0.316
uM
 72
hr
 1 1414 87 0.4328 0.7091 0.0615 0.0504
MZ7-mel Vemurafenib Saracatinib 0.100 0.316
uM
 72
hr
 2 2523 106 0.7883 0.7091 0.0420 0.0504
MZ7-mel Vemurafenib Saracatinib 0.100 0.316
uM
 72
hr
 3 2917 139 0.9061 0.7091 0.0477 0.0504
MZ7-mel Vemurafenib Saracatinib 0.100 1.000
uM
 72
hr
 1 2405 95 0.7534 0.5199 0.0395 0.0507
MZ7-mel Vemurafenib Saracatinib 0.100 1.000
uM
 72
hr
 2 1676 76 0.5219 0.5199 0.0453 0.0507
MZ7-mel Vemurafenib Saracatinib 0.100 1.000
uM
 72
hr
 3 935 63 0.2844 0.5199 0.0674 0.0507
MZ7-mel Vemurafenib Saracatinib 0.100 3.160
uM
 72
hr
 1 2740 133 0.8503 0.6154 0.0485 0.0443
MZ7-mel Vemurafenib Saracatinib 0.100 3.160
uM
 72
hr
 2 2133 89 0.6667 0.6154 0.0417 0.0443
MZ7-mel Vemurafenib Saracatinib 0.100 3.160
uM
 72
hr
 3 1054 45 0.3291 0.6154 0.0427 0.0443
MZ7-mel Vemurafenib Saracatinib 0.316 0.000
uM
 72
hr
 1 1177 92 0.3539 0.5276 0.0782 0.0734
MZ7-mel Vemurafenib Saracatinib 0.316 0.000
uM
 72
hr
 2 1811 126 0.5496 0.5276 0.0696 0.0734
MZ7-mel Vemurafenib Saracatinib 0.316 0.000
uM
 72
hr
 3 2246 163 0.6794 0.5276 0.0726 0.0734
MZ7-mel Vemurafenib Saracatinib 0.316 0.316
uM
 72
hr
 1 1274 83 0.3885 0.4386 0.0651 0.0724
MZ7-mel Vemurafenib Saracatinib 0.316 0.316
uM
 72
hr
 2 1259 96 0.3793 0.4386 0.0763 0.0724
MZ7-mel Vemurafenib Saracatinib 0.316 0.316
uM
 72
hr
 3 1818 138 0.5479 0.4386 0.0759 0.0724
MZ7-mel Vemurafenib Saracatinib 0.316 1.000
uM
 72
hr
 1 2062 135 0.6285 0.4197 0.0655 0.0627
MZ7-mel Vemurafenib Saracatinib 0.316 1.000
uM
 72
hr
 2 1409 72 0.4361 0.4197 0.0511 0.0627
MZ7-mel Vemurafenib Saracatinib 0.316 1.000
uM
 72
hr
 3 642 46 0.1944 0.4197 0.0717 0.0627
MZ7-mel Vemurafenib Saracatinib 0.316 3.160
uM
 72
hr
 1 1603 97 0.4912 0.3835 0.0605 0.0574
MZ7-mel Vemurafenib Saracatinib 0.316 3.160
uM
 72
hr
 2 1453 82 0.4472 0.3835 0.0564 0.0574