Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (viability/apoptosis dataset 1 of 2) - Dataset (ID:20272)

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Cell Small Molecule 1 Small Molecule 2 Small Mol 1 Concentration Small Mol 2 Concentration Small Mol Conc Unit Time Point Time Point Unit Replicate Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction
MZ7-mel Vemurafenib Saracatinib 0.316 3.160
uM
 72
hr
 3 688 38 0.2120 0.3835 0.0552 0.0574
MZ7-mel Vemurafenib Saracatinib 1.000 0.000
uM
 72
hr
 1 973 157 0.2661 0.4331 0.1614 0.1398
MZ7-mel Vemurafenib Saracatinib 1.000 0.000
uM
 72
hr
 2 1459 185 0.4155 0.4331 0.1268 0.1398
MZ7-mel Vemurafenib Saracatinib 1.000 0.000
uM
 72
hr
 3 2180 286 0.6177 0.4331 0.1312 0.1398
MZ7-mel Vemurafenib Saracatinib 1.000 0.316
uM
 72
hr
 1 832 108 0.2361 0.2764 0.1298 0.1279
MZ7-mel Vemurafenib Saracatinib 1.000 0.316
uM
 72
hr
 2 969 132 0.2730 0.2764 0.1362 0.1279
MZ7-mel Vemurafenib Saracatinib 1.000 0.316
uM
 72
hr
 3 1112 131 0.3200 0.2764 0.1178 0.1279
MZ7-mel Vemurafenib Saracatinib 1.000 1.000
uM
 72
hr
 1 1778 219 0.5085 0.3290 0.1232 0.1295
MZ7-mel Vemurafenib Saracatinib 1.000 1.000
uM
 72
hr
 2 1096 139 0.3121 0.3290 0.1268 0.1295
MZ7-mel Vemurafenib Saracatinib 1.000 1.000
uM
 72
hr
 3 592 82 0.1663 0.3290 0.1385 0.1295
MZ7-mel Vemurafenib Saracatinib 1.000 3.160
uM
 72
hr
 1 1033 143 0.2903 0.2489 0.1384 0.1284
MZ7-mel Vemurafenib Saracatinib 1.000 3.160
uM
 72
hr
 2 1051 139 0.2975 0.2489 0.1323 0.1284
MZ7-mel Vemurafenib Saracatinib 1.000 3.160
uM
 72
hr
 3 550 63 0.1588 0.2489 0.1145 0.1284
MZ7-mel Vemurafenib Saracatinib 3.160 0.000
uM
 72
hr
 1 839 282 0.1817 0.3021 0.3361 0.3372
MZ7-mel Vemurafenib Saracatinib 3.160 0.000
uM
 72
hr
 2 1465 510 0.3115 0.3021 0.3481 0.3372
MZ7-mel Vemurafenib Saracatinib 3.160 0.000
uM
 72
hr
 3 1884 617 0.4132 0.3021 0.3275 0.3372
MZ7-mel Vemurafenib Saracatinib 3.160 0.316
uM
 72
hr
 1 511 140 0.1210 0.1227 0.2740 0.2535
MZ7-mel Vemurafenib Saracatinib 3.160 0.316
uM
 72
hr
 2 508 135 0.1217 0.1227 0.2657 0.2535
MZ7-mel Vemurafenib Saracatinib 3.160 0.316
uM
 72
hr
 3 494 109 0.1256 0.1227 0.2206 0.2535
MZ7-mel Vemurafenib Saracatinib 3.160 1.000
uM
 72
hr
 1 1809 601 0.3940 0.2445 0.3322 0.3329
MZ7-mel Vemurafenib Saracatinib 3.160 1.000
uM
 72
hr
 2 1072 372 0.2283 0.2445 0.3470 0.3329
MZ7-mel Vemurafenib Saracatinib 3.160 1.000
uM
 72
hr
 3 501 160 0.1112 0.2445 0.3194 0.3329
MZ7-mel Vemurafenib Saracatinib 3.160 3.160
uM
 72
hr
 1 447 138 0.1008 0.1000 0.3087 0.3467
MZ7-mel Vemurafenib Saracatinib 3.160 3.160
uM
 72
hr
 2 488 174 0.1024 0.1000 0.3566 0.3467
MZ7-mel Vemurafenib Saracatinib 3.160 3.160
uM
 72
hr
 3 475 178 0.0969 0.1000 0.3747 0.3467