Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1143 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7430.098 | 0.7116 | 0.6763 | 1.9267 | |
| HCC1143 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7430.098 | 0.3004 | 0.0714 | 1.9267 | |
| HCC1143 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7430.098 | 0.4990 | 0.3942 | 1.9267 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7431.092 | 1.0086 | 1.0114 | 1.5006 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7431.092 | 0.9769 | 0.9691 | 1.5006 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7431.092 | 0.9369 | 0.9149 | 1.5006 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7431.092 | 0.8989 | 0.8629 | 1.5006 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7431.092 | 0.9554 | 0.9400 | 1.5006 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7431.092 | 0.7479 | 0.6480 | 1.5006 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7431.092 | 0.6931 | 0.5665 | 1.5006 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7431.092 | 0.0318 | -0.7993 | 1.5006 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7431.092 | 0.0100 | -0.9070 | 1.5006 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7431.098 | 1.0193 | 1.0254 | 1.5161 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7431.098 | 0.9969 | 0.9960 | 1.5161 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7431.098 | 1.0090 | 1.0118 | 1.5161 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7431.098 | 0.9783 | 0.9712 | 1.5161 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7431.098 | 0.9136 | 0.8843 | 1.5161 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7431.098 | 0.8427 | 0.7865 | 1.5161 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7431.098 | 0.7233 | 0.6152 | 1.5161 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7431.098 | 0.2319 | -0.2372 | 1.5161 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7431.098 | 0.0124 | -0.8893 | 1.5161 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.000307 | uM | 7432.071 | 0.9927 | 0.9848 | 0.9599 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.00154 | uM | 7432.071 | 0.9555 | 0.9074 | 0.9599 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.00768 | uM | 7432.071 | 1.0117 | 1.0244 | 0.9599 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.0384 | uM | 7432.071 | 1.0432 | 1.0900 | 0.9599 |