Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AU565 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 133 | uM | 5901.091 | 0.3877 | 0.2219 | 1.9229 | |
| AU565 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 5901.098 | 0.9854 | 0.9837 | 1.8013 | |
| AU565 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 5901.098 | 1.0043 | 1.0048 | 1.8013 | |
| AU565 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 5901.098 | 0.9658 | 0.9618 | 1.8013 | |
| AU565 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 5901.098 | 0.9700 | 0.9665 | 1.8013 | |
| AU565 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.107 | uM | 5901.098 | 0.9521 | 0.9462 | 1.8013 | |
| AU565 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.533 | uM | 5901.098 | 0.9705 | 0.9670 | 1.8013 | |
| AU565 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 2.67 | uM | 5901.098 | 0.5541 | 0.4411 | 1.8013 | |
| AU565 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 13.3 | uM | 5901.098 | 0.0282 | -0.7241 | 1.8013 | |
| AU565 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 66.7 | uM | 5901.098 | 0.0078 | -0.8645 | 1.8013 | |
| BT-20 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.000307 | uM | 5902.071 | 1.1319 | 1.2339 | 1.1197 | |
| BT-20 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.00154 | uM | 5902.071 | 1.0119 | 1.0213 | 1.1197 | |
| BT-20 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.00768 | uM | 5902.071 | 1.0366 | 1.0652 | 1.1197 | |
| BT-20 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.0384 | uM | 5902.071 | 1.0062 | 1.0110 | 1.1197 | |
| BT-20 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.192 | uM | 5902.071 | 1.0879 | 1.1563 | 1.1197 | |
| BT-20 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.96 | uM | 5902.071 | 1.0634 | 1.1128 | 1.1197 | |
| BT-20 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 4.8 | uM | 5902.071 | 1.0864 | 1.1536 | 1.1197 | |
| BT-20 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 24 | uM | 5902.071 | 0.4049 | -0.1081 | 1.1197 | |
| BT-20 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 120 | uM | 5902.071 | 1.0431 | 1.0768 | 1.1197 | |
| BT-20 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 5902.091 | 1.0740 | 1.1264 | 1.1648 | |
| BT-20 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 5902.091 | 0.9971 | 0.9951 | 1.1648 | |
| BT-20 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 5902.091 | 1.0530 | 1.0907 | 1.1648 | |
| BT-20 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 5902.091 | 1.0189 | 1.0324 | 1.1648 | |
| BT-20 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.213 | uM | 5902.091 | 1.0035 | 1.0061 | 1.1648 | |
| BT-20 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 1.07 | uM | 5902.091 | 1.0164 | 1.0281 | 1.1648 |