Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T47D | HR+ | Luminal | GSK1070916 | AURK | AURK | 0.000427 | uM | 9897.001 | 0.9983 | 0.9935 | 0.5223 | |
| T47D | HR+ | Luminal | GSK1070916 | AURK | AURK | 0.00213 | uM | 9897.001 | 1.0227 | 1.0878 | 0.5223 | |
| T47D | HR+ | Luminal | GSK1070916 | AURK | AURK | 0.0107 | uM | 9897.001 | 1.0201 | 1.0777 | 0.5223 | |
| T47D | HR+ | Luminal | GSK1070916 | AURK | AURK | 0.0533 | uM | 9897.001 | 0.9337 | 0.7538 | 0.5223 | |
| T47D | HR+ | Luminal | GSK1070916 | AURK | AURK | 0.267 | uM | 9897.001 | 0.9058 | 0.6547 | 0.5223 | |
| T47D | HR+ | Luminal | GSK1070916 | AURK | AURK | 1.33 | uM | 9897.001 | 0.9251 | 0.7229 | 0.5223 | |
| T47D | HR+ | Luminal | GSK1070916 | AURK | AURK | 6.67 | uM | 9897.001 | 0.7991 | 0.3018 | 0.5223 | |
| T47D | HR+ | Luminal | GSK1070916 | AURK | AURK | 33.3 | uM | 9897.001 | 0.2606 | -0.8477 | 0.5223 | |
| UACC-812 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.0000853 | uM | 7926.001 | 1.1457 | 1.3784 | 0.7852 | |
| UACC-812 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.000427 | uM | 7926.001 | 1.0529 | 1.1357 | 0.7852 | |
| UACC-812 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.00213 | uM | 7926.001 | 1.1573 | 1.4091 | 0.7852 | |
| UACC-812 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.0107 | uM | 7926.001 | 1.0007 | 1.0019 | 0.7852 | |
| UACC-812 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.0533 | uM | 7926.001 | 1.0045 | 1.0116 | 0.7852 | |
| UACC-812 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.267 | uM | 7926.001 | 0.9697 | 0.9230 | 0.7852 | |
| UACC-812 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 1.33 | uM | 7926.001 | 1.1298 | 1.3364 | 0.7852 | |
| UACC-812 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 6.67 | uM | 7926.001 | 1.0561 | 1.1439 | 0.7852 | |
| UACC-812 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 33.3 | uM | 7926.001 | 0.7136 | 0.3012 | 0.7852 | |
| UACC-812 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.0000853 | uM | 9913.001 | 1.2038 | 2.6765 | 0.3047 | |
| UACC-812 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.000427 | uM | 9913.001 | 0.9683 | 0.7994 | 0.3047 | |
| UACC-812 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.00213 | uM | 9913.001 | 1.1735 | 2.3812 | 0.3047 | |
| UACC-812 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.0107 | uM | 9913.001 | 1.1083 | 1.8026 | 0.3047 | |
| UACC-812 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.0533 | uM | 9913.001 | 1.0842 | 1.6080 | 0.3047 | |
| UACC-812 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.267 | uM | 9913.001 | 1.0773 | 1.5535 | 0.3047 | |
| UACC-812 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 1.33 | uM | 9913.001 | 1.0439 | 1.3030 | 0.3047 | |
| UACC-812 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 6.67 | uM | 9913.001 | 1.0883 | 1.6398 | 0.3047 |