Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC2185 | TNBC | Luminal | GSK461364 | PLK1 | PLK | 1.33 | uM | 7848.001 | 0.5772 | -0.4027 | 0.4548 | |
| HCC2185 | TNBC | Luminal | GSK461364 | PLK1 | PLK | 6.67 | uM | 7848.001 | 0.6446 | -0.2385 | 0.4548 | |
| HCC2185 | TNBC | Luminal | GSK461364 | PLK1 | PLK | 33.3 | uM | 7848.001 | 0.3539 | -0.7963 | 0.4548 | |
| HCC2185 | TNBC | Luminal | GSK461364 | PLK1 | PLK | 0.0000853 | uM | 7849.001 | 1.0282 | 1.1076 | 0.5308 | |
| HCC2185 | TNBC | Luminal | GSK461364 | PLK1 | PLK | 0.000427 | uM | 7849.001 | 1.0359 | 1.1375 | 0.5308 | |
| HCC2185 | TNBC | Luminal | GSK461364 | PLK1 | PLK | 0.00213 | uM | 7849.001 | 0.5724 | -0.3009 | 0.5308 | |
| HCC2185 | TNBC | Luminal | GSK461364 | PLK1 | PLK | 0.0107 | uM | 7849.001 | 0.5512 | -0.3488 | 0.5308 | |
| HCC2185 | TNBC | Luminal | GSK461364 | PLK1 | PLK | 0.0533 | uM | 7849.001 | 0.5520 | -0.3472 | 0.5308 | |
| HCC2185 | TNBC | Luminal | GSK461364 | PLK1 | PLK | 0.267 | uM | 7849.001 | 0.6046 | -0.2248 | 0.5308 | |
| HCC2185 | TNBC | Luminal | GSK461364 | PLK1 | PLK | 1.33 | uM | 7849.001 | 0.6329 | -0.1552 | 0.5308 | |
| HCC2185 | TNBC | Luminal | GSK461364 | PLK1 | PLK | 6.67 | uM | 7849.001 | 0.6489 | -0.1144 | 0.5308 | |
| HCC2185 | TNBC | Luminal | GSK461364 | PLK1 | PLK | 33.3 | uM | 7849.001 | 0.1911 | -0.9115 | 0.5308 | |
| HCC2185 | TNBC | Luminal | GSK461364 | PLK1 | PLK | 0.0000853 | uM | 9420.001 | 1.0055 | 1.0334 | 0.3332 | |
| HCC2185 | TNBC | Luminal | GSK461364 | PLK1 | PLK | 0.000427 | uM | 9420.001 | 1.0132 | 1.0800 | 0.3332 | |
| HCC2185 | TNBC | Luminal | GSK461364 | PLK1 | PLK | 0.00213 | uM | 9420.001 | 0.9676 | 0.8115 | 0.3332 | |
| HCC2185 | TNBC | Luminal | GSK461364 | PLK1 | PLK | 0.0107 | uM | 9420.001 | 0.7951 | 0.0049 | 0.3332 | |
| HCC2185 | TNBC | Luminal | GSK461364 | PLK1 | PLK | 0.0533 | uM | 9420.001 | 0.6072 | -0.5525 | 0.3332 | |
| HCC2185 | TNBC | Luminal | GSK461364 | PLK1 | PLK | 0.267 | uM | 9420.001 | 0.6462 | -0.4605 | 0.3332 | |
| HCC2185 | TNBC | Luminal | GSK461364 | PLK1 | PLK | 1.33 | uM | 9420.001 | 0.7146 | -0.2705 | 0.3332 | |
| HCC2185 | TNBC | Luminal | GSK461364 | PLK1 | PLK | 6.67 | uM | 9420.001 | 0.6929 | -0.3349 | 0.3332 | |
| HCC2185 | TNBC | Luminal | GSK461364 | PLK1 | PLK | 33.3 | uM | 9420.001 | 0.5608 | -0.6476 | 0.3332 | |
| HCC2185 | TNBC | Luminal | GSK461364 | PLK1 | PLK | 0.0000853 | uM | 10263.001 | 1.0265 | 1.1673 | 0.3258 | |
| HCC2185 | TNBC | Luminal | GSK461364 | PLK1 | PLK | 0.000427 | uM | 10263.001 | 1.0433 | 1.2776 | 0.3258 | |
| HCC2185 | TNBC | Luminal | GSK461364 | PLK1 | PLK | 0.00213 | uM | 10263.001 | 1.0103 | 1.0637 | 0.3258 | |
| HCC2185 | TNBC | Luminal | GSK461364 | PLK1 | PLK | 0.0107 | uM | 10263.001 | 0.5167 | -0.7364 | 0.3258 |