Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAMA-1 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 66.7 | uM | 5912.098 | 0.9360 | 0.8785 | 1.0559 | |
| HBL-100 | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 7429.09 | 1.0427 | 1.0376 | 2.2456 | |
| HBL-100 | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 7429.09 | 1.0002 | 1.0001 | 2.2456 | |
| HBL-100 | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 7429.09 | 1.0394 | 1.0347 | 2.2456 | |
| HBL-100 | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 7429.09 | 1.0144 | 1.0128 | 2.2456 | |
| HBL-100 | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.213 | uM | 7429.09 | 0.9885 | 0.9897 | 2.2456 | |
| HBL-100 | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 1.07 | uM | 7429.09 | 0.8985 | 0.9069 | 2.2456 | |
| HBL-100 | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 5.33 | uM | 7429.09 | 0.7622 | 0.7722 | 2.2456 | |
| HBL-100 | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 26.7 | uM | 7429.09 | 0.5428 | 0.5236 | 2.2456 | |
| HBL-100 | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 133 | uM | 7429.09 | 0.2953 | 0.1619 | 2.2456 | |
| HCC1143 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 7430.091 | 1.0338 | 1.0380 | 1.7667 | |
| HCC1143 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 7430.091 | 1.0458 | 1.0513 | 1.7667 | |
| HCC1143 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 7430.091 | 1.0376 | 1.0422 | 1.7667 | |
| HCC1143 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 7430.091 | 1.1194 | 1.1318 | 1.7667 | |
| HCC1143 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.213 | uM | 7430.091 | 1.0096 | 1.0109 | 1.7667 | |
| HCC1143 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 1.07 | uM | 7430.091 | 0.7097 | 0.6472 | 1.7667 | |
| HCC1143 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 5.33 | uM | 7430.091 | 0.4648 | 0.2963 | 1.7667 | |
| HCC1143 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 26.7 | uM | 7430.091 | 0.0121 | -0.8354 | 1.7667 | |
| HCC1143 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 133 | uM | 7430.091 | 0.0111 | -0.8432 | 1.7667 | |
| HCC1143 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7430.098 | 1.0065 | 1.0067 | 1.9267 | |
| HCC1143 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7430.098 | 1.0176 | 1.0182 | 1.9267 | |
| HCC1143 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7430.098 | 1.0229 | 1.0237 | 1.9267 | |
| HCC1143 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7430.098 | 1.0106 | 1.0110 | 1.9267 | |
| HCC1143 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7430.098 | 0.9978 | 0.9977 | 1.9267 | |
| HCC1143 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7430.098 | 0.9419 | 0.9388 | 1.9267 |