Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.192 | uM | 7432.071 | 0.8810 | 0.7527 | 0.9599 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.96 | uM | 7432.071 | 0.8178 | 0.6218 | 0.9599 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 4.8 | uM | 7432.071 | 0.3760 | -0.2782 | 0.9599 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 24 | uM | 7432.071 | 0.0099 | -0.9837 | 0.9599 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 120 | uM | 7432.071 | 0.0104 | -0.9829 | 0.9599 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 7432.091 | 1.0749 | 1.1464 | 1.0227 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 7432.091 | 1.0076 | 1.0148 | 1.0227 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 7432.091 | 0.9564 | 0.9146 | 1.0227 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 7432.091 | 0.9078 | 0.8195 | 1.0227 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.213 | uM | 7432.091 | 0.9578 | 0.9174 | 1.0227 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 1.07 | uM | 7432.091 | 0.7893 | 0.5868 | 1.0227 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 5.33 | uM | 7432.091 | 0.4128 | -0.1581 | 1.0227 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 26.7 | uM | 7432.091 | 0.0135 | -0.9702 | 1.0227 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 133 | uM | 7432.091 | 0.0087 | -0.9807 | 1.0227 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7432.098 | 1.0099 | 1.0191 | 1.0423 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7432.098 | 0.9650 | 0.9328 | 1.0423 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7432.098 | 1.0479 | 1.0918 | 1.0423 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7432.098 | 0.9948 | 0.9900 | 1.0423 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7432.098 | 0.9352 | 0.8755 | 1.0423 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7432.098 | 0.8976 | 0.8031 | 1.0423 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7432.098 | 0.6814 | 0.3842 | 1.0423 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7432.098 | 0.0080 | -0.9806 | 1.0423 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7432.098 | 0.6933 | 0.4074 | 1.0423 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.000307 | uM | 7433.071 | 1.0431 | 1.0828 | 1.0393 | |
| HCC1187 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.00154 | uM | 7433.071 | 0.9891 | 0.9790 | 1.0393 |