LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF7 Dovitinib
0.12
uM
LJP5
 72
hr
 1235 3441 4267 0.8060 0.7715
MCF7 Dovitinib
0.37
uM
LJP5
 72
hr
 1235 3010 4267 0.7052 0.6448
MCF7 Dovitinib
1.11
uM
LJP5
 72
hr
 1235 2849 4267 0.6681 0.5960
MCF7 Dovitinib
3.33
uM
LJP5
 72
hr
 1235 2215 4267 0.5192 0.3861
MCF7 Dovitinib
10
uM
LJP5
 72
hr
 1235 2197 4267 0.5152 0.3802
MCF7 GSK 690693
0.04
uM
LJP5
 72
hr
 1235 2655 4267 0.6212 0.5305
MCF7 GSK 690693
0.12
uM
LJP5
 72
hr
 1235 2213 4267 0.5185 0.3840
MCF7 GSK 690693
0.37
uM
LJP5
 72
hr
 1235 2168 4267 0.5080 0.3685
MCF7 GSK 690693
1.11
uM
LJP5
 72
hr
 1235 2108 4267 0.4937 0.3469
MCF7 GSK 690693
3.33
uM
LJP5
 72
hr
 1235 2231 4267 0.5228 0.3912
MCF7 GSK 690693
10
uM
LJP5
 72
hr
 1235 2142 4267 0.5018 0.3581
MCF7 SNS-032
0.04
uM
LJP6
 72
hr
 1235 726 4056 0.1789 -0.2671
MCF7 SNS-032
0.12
uM
LJP6
 72
hr
 1235 632 4056 0.1555 -0.3278
MCF7 SNS-032
0.37
uM
LJP6
 72
hr
 1235 574 4056 0.1415 -0.3617
MCF7 SNS-032
1.11
uM
LJP6
 72
hr
 1235 565 4056 0.1396 -0.3669
MCF7 SNS-032
3.33
uM
LJP6
 72
hr
 1235 579 4056 0.1425 -0.3583
MCF7 SNS-032
10
uM
LJP6
 72
hr
 1235 598 4056 0.1476 -0.3446
MCF7 Afatinib
0.04
uM
LJP6
 72
hr
 1235 2830 4056 0.6983 0.6221
MCF7 Afatinib
0.12
uM
LJP6
 72
hr
 1235 2890 4056 0.7125 0.6409
MCF7 Afatinib
0.37
uM
LJP6
 72
hr
 1235 3301 4056 0.8145 0.7745
MCF7 Afatinib
1.11
uM
LJP6
 72
hr
 1235 3186 4056 0.7852 0.7355
MCF7 Afatinib
3.33
uM
LJP6
 72
hr
 1235 2283 4056 0.5630 0.4305
MCF7 Afatinib
10
uM
LJP6
 72
hr
 1235 664 4056 0.1637 -0.3041
MCF7 GSK1904529A
0.04
uM
LJP6
 72
hr
 1235 1953 4056 0.4815 0.3061
MCF7 GSK1904529A
0.12
uM
LJP6
 72
hr
 1235 1785 4056 0.4400 0.2390