LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | CP466722 | 10 | uM | LJP5 | 72 | hr | 1476 | 1885 | 3772 | 0.4998 | 0.1978 |
| SK-BR-3 | CP724714 | 0.04 | uM | LJP5 | 72 | hr | 1476 | 2221 | 3772 | 0.5889 | 0.3522 |
| SK-BR-3 | CP724714 | 0.12 | uM | LJP5 | 72 | hr | 1476 | 2084 | 3772 | 0.5526 | 0.2900 |
| SK-BR-3 | CP724714 | 0.37 | uM | LJP5 | 72 | hr | 1476 | 1797 | 3772 | 0.4767 | 0.1561 |
| SK-BR-3 | CP724714 | 1.11 | uM | LJP5 | 72 | hr | 1476 | 1692 | 3772 | 0.4486 | 0.1052 |
| SK-BR-3 | CP724714 | 3.33 | uM | LJP5 | 72 | hr | 1476 | 1595 | 3772 | 0.4230 | 0.0586 |
| SK-BR-3 | CP724714 | 10 | uM | LJP5 | 72 | hr | 1476 | 1297 | 3772 | 0.3440 | -0.0913 |
| SK-BR-3 | Alvocidib | 0.04 | uM | LJP6 | 72 | hr | 1476 | 1630 | 3643 | 0.4489 | 0.0803 |
| SK-BR-3 | Alvocidib | 0.12 | uM | LJP6 | 72 | hr | 1476 | 1219 | 3643 | 0.3368 | -0.1356 |
| SK-BR-3 | Alvocidib | 0.37 | uM | LJP6 | 72 | hr | 1476 | 1225 | 3643 | 0.3381 | -0.1326 |
| SK-BR-3 | Alvocidib | 1.11 | uM | LJP6 | 72 | hr | 1476 | 981 | 3643 | 0.2703 | -0.2707 |
| SK-BR-3 | Alvocidib | 3.33 | uM | LJP6 | 72 | hr | 1476 | 1080 | 3643 | 0.2984 | -0.2124 |
| SK-BR-3 | Alvocidib | 10 | uM | LJP6 | 72 | hr | 1476 | 861 | 3643 | 0.2372 | -0.3403 |
| SK-BR-3 | GW843682X | 0.04 | uM | LJP6 | 72 | hr | 1476 | 3249 | 3643 | 0.8925 | 0.8335 |
| SK-BR-3 | GW843682X | 0.12 | uM | LJP6 | 72 | hr | 1476 | 2171 | 3643 | 0.5976 | 0.3471 |
| SK-BR-3 | GW843682X | 0.37 | uM | LJP6 | 72 | hr | 1476 | 1355 | 3643 | 0.3731 | -0.0634 |
| SK-BR-3 | GW843682X | 1.11 | uM | LJP6 | 72 | hr | 1476 | 1355 | 3643 | 0.3728 | -0.0639 |
| SK-BR-3 | GW843682X | 3.33 | uM | LJP6 | 72 | hr | 1476 | 1194 | 3643 | 0.3284 | -0.1512 |
| SK-BR-3 | GW843682X | 10 | uM | LJP6 | 72 | hr | 1476 | 2206 | 3643 | 0.6083 | 0.3663 |
| SK-BR-3 | HG-5-113-01 | 0.04 | uM | LJP5 | 72 | hr | 1476 | 3278 | 3772 | 0.8691 | 0.8029 |
| SK-BR-3 | HG-5-113-01 | 0.12 | uM | LJP5 | 72 | hr | 1476 | 2848 | 3772 | 0.7553 | 0.6252 |
| SK-BR-3 | HG-5-113-01 | 0.37 | uM | LJP5 | 72 | hr | 1476 | 1830 | 3772 | 0.4850 | 0.1711 |
| SK-BR-3 | HG-5-113-01 | 1.11 | uM | LJP5 | 72 | hr | 1476 | 1323 | 3772 | 0.3508 | -0.0783 |
| SK-BR-3 | HG-5-113-01 | 3.33 | uM | LJP5 | 72 | hr | 1476 | 1177 | 3772 | 0.3122 | -0.1541 |
| SK-BR-3 | HG-5-113-01 | 10 | uM | LJP5 | 72 | hr | 1476 | 1296 | 3772 | 0.3438 | -0.0920 |