LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Enzastaurin | 1.11 | uM | LJP5 | 72 | hr | 1476 | 4019 | 3772 | 1.0657 | 1.0964 |
| SK-BR-3 | Enzastaurin | 3.33 | uM | LJP5 | 72 | hr | 1476 | 4054 | 3772 | 1.0749 | 1.1099 |
| SK-BR-3 | Enzastaurin | 10 | uM | LJP5 | 72 | hr | 1476 | 3209 | 3772 | 0.8517 | 0.7609 |
| SK-BR-3 | Palbociclib | 0.04 | uM | LJP6 | 72 | hr | 1476 | 3486 | 3643 | 0.9591 | 0.9400 |
| SK-BR-3 | Palbociclib | 0.12 | uM | LJP6 | 72 | hr | 1476 | 2997 | 3643 | 0.8234 | 0.7230 |
| SK-BR-3 | Palbociclib | 0.37 | uM | LJP6 | 72 | hr | 1476 | 2860 | 3643 | 0.7875 | 0.6669 |
| SK-BR-3 | Palbociclib | 1.11 | uM | LJP6 | 72 | hr | 1476 | 2716 | 3643 | 0.7453 | 0.5939 |
| SK-BR-3 | Palbociclib | 3.33 | uM | LJP6 | 72 | hr | 1476 | 2765 | 3643 | 0.7608 | 0.6223 |
| SK-BR-3 | Palbociclib | 10 | uM | LJP6 | 72 | hr | 1476 | 2583 | 3643 | 0.7103 | 0.5384 |
| SK-BR-3 | PF562271 | 0.04 | uM | LJP6 | 72 | hr | 1476 | 3808 | 3643 | 1.0471 | 1.0753 |
| SK-BR-3 | PF562271 | 0.12 | uM | LJP6 | 72 | hr | 1476 | 3704 | 3643 | 1.0201 | 1.0354 |
| SK-BR-3 | PF562271 | 0.37 | uM | LJP6 | 72 | hr | 1476 | 2980 | 3643 | 0.8171 | 0.7106 |
| SK-BR-3 | PF562271 | 1.11 | uM | LJP6 | 72 | hr | 1476 | 1783 | 3643 | 0.4900 | 0.1550 |
| SK-BR-3 | PF562271 | 3.33 | uM | LJP6 | 72 | hr | 1476 | 1361 | 3643 | 0.3741 | -0.0615 |
| SK-BR-3 | PF562271 | 10 | uM | LJP6 | 72 | hr | 1476 | 1246 | 3643 | 0.3435 | -0.1212 |
| SK-BR-3 | PHA-793887 | 0.04 | uM | LJP6 | 72 | hr | 1476 | 1591 | 3643 | 0.4380 | 0.0599 |
| SK-BR-3 | PHA-793887 | 0.12 | uM | LJP6 | 72 | hr | 1476 | 1583 | 3643 | 0.4353 | 0.0548 |
| SK-BR-3 | PHA-793887 | 0.37 | uM | LJP6 | 72 | hr | 1476 | 1524 | 3643 | 0.4188 | 0.0236 |
| SK-BR-3 | PHA-793887 | 1.11 | uM | LJP6 | 72 | hr | 1476 | 1536 | 3643 | 0.4217 | 0.0289 |
| SK-BR-3 | PHA-793887 | 3.33 | uM | LJP6 | 72 | hr | 1476 | 1437 | 3643 | 0.3952 | -0.0209 |
| SK-BR-3 | PHA-793887 | 10 | uM | LJP6 | 72 | hr | 1476 | 1049 | 3643 | 0.2889 | -0.2320 |
| SK-BR-3 | QL-X-138 | 0.04 | uM | LJP6 | 72 | hr | 1476 | 2215 | 3643 | 0.6086 | 0.3643 |
| SK-BR-3 | QL-X-138 | 0.12 | uM | LJP6 | 72 | hr | 1476 | 2124 | 3643 | 0.5834 | 0.3210 |
| SK-BR-3 | QL-X-138 | 0.37 | uM | LJP6 | 72 | hr | 1476 | 1877 | 3643 | 0.5151 | 0.2002 |
| SK-BR-3 | QL-X-138 | 1.11 | uM | LJP6 | 72 | hr | 1476 | 1894 | 3643 | 0.5207 | 0.2108 |