LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF7 GSK1904529A
0.37
uM
LJP6
 72
hr
 1235 1968 4056 0.4854 0.3121
MCF7 GSK1904529A
1.11
uM
LJP6
 72
hr
 1235 1904 4056 0.4695 0.2870
MCF7 GSK1904529A
3.33
uM
LJP6
 72
hr
 1235 1945 4056 0.4793 0.3020
MCF7 GSK1904529A
10
uM
LJP6
 72
hr
 1235 1742 4056 0.4291 0.2201
MCF7 Linsitinib
0.04
uM
LJP5
 72
hr
 1235 3243 4267 0.7593 0.7122
MCF7 Linsitinib
0.12
uM
LJP5
 72
hr
 1235 3268 4267 0.7670 0.7244
MCF7 Linsitinib
0.37
uM
LJP5
 72
hr
 1235 2401 4267 0.5632 0.4504
MCF7 Linsitinib
1.11
uM
LJP5
 72
hr
 1235 2251 4267 0.5279 0.3984
MCF7 Linsitinib
3.33
uM
LJP5
 72
hr
 1235 2187 4267 0.5122 0.3740
MCF7 Linsitinib
10
uM
LJP5
 72
hr
 1235 1868 4267 0.4376 0.2591
MCF7 Ruxolitinib
0.04
uM
LJP5
 72
hr
 1235 3891 4267 0.9125 0.9001
MCF7 Ruxolitinib
0.12
uM
LJP5
 72
hr
 1235 3957 4267 0.9270 0.9166
MCF7 Ruxolitinib
0.37
uM
LJP5
 72
hr
 1235 3973 4267 0.9305 0.9195
MCF7 Ruxolitinib
1.11
uM
LJP5
 72
hr
 1235 4302 4267 1.0077 1.0077
MCF7 Ruxolitinib
3.33
uM
LJP5
 72
hr
 1235 4398 4267 1.0299 1.0321
MCF7 Ruxolitinib
10
uM
LJP5
 72
hr
 1235 3184 4267 0.7457 0.6961
MCF7 Momelotinib
0.04
uM
LJP5
 72
hr
 1235 3936 4267 0.9212 0.9070
MCF7 Momelotinib
0.12
uM
LJP5
 72
hr
 1235 3478 4267 0.8150 0.7837
MCF7 Momelotinib
0.37
uM
LJP5
 72
hr
 1235 3297 4267 0.7735 0.7326
MCF7 Momelotinib
1.11
uM
LJP5
 72
hr
 1235 2804 4267 0.6573 0.5808
MCF7 Momelotinib
3.33
uM
LJP5
 72
hr
 1235 1785 4267 0.4184 0.2277
MCF7 Momelotinib
10
uM
LJP5
 72
hr
 1235 1411 4267 0.3310 0.0775
MCF7 Fedratinib
0.04
uM
LJP5
 72
hr
 1235 4587 4267 1.0724 1.0751
MCF7 Fedratinib
0.12
uM
LJP5
 72
hr
 1235 4228 4267 0.9906 0.9892
MCF7 Fedratinib
0.37
uM
LJP5
 72
hr
 1235 3512 4267 0.8238 0.7932