LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF7 AZD-6482
3.33
uM
LJP5
 72
hr
 1235 2813 4267 0.6594 0.5841
MCF7 AZD-6482
10
uM
LJP5
 72
hr
 1235 1087 4267 0.2548 -0.0694
MCF7 NU7441
0.04
uM
LJP5
 72
hr
 1235 4252 4267 0.9971 0.9971
MCF7 NU7441
0.12
uM
LJP5
 72
hr
 1235 4160 4267 0.9765 0.9738
MCF7 NU7441
0.37
uM
LJP5
 72
hr
 1235 4230 4267 0.9920 0.9913
MCF7 NU7441
1.11
uM
LJP5
 72
hr
 1235 3783 4267 0.8868 0.8700
MCF7 NU7441
3.33
uM
LJP5
 72
hr
 1235 3178 4267 0.7458 0.6974
MCF7 NU7441
10
uM
LJP5
 72
hr
 1235 1574 4267 0.3689 0.1448
MCF7 OSI-027
0.04
uM
LJP6
 72
hr
 1235 3766 4056 0.9282 0.9145
MCF7 OSI-027
0.12
uM
LJP6
 72
hr
 1235 3019 4056 0.7440 0.6826
MCF7 OSI-027
0.37
uM
LJP6
 72
hr
 1235 2071 4056 0.5101 0.3498
MCF7 OSI-027
1.11
uM
LJP6
 72
hr
 1235 1974 4056 0.4869 0.3141
MCF7 OSI-027
3.33
uM
LJP6
 72
hr
 1235 1789 4056 0.4414 0.2411
MCF7 OSI-027
10
uM
LJP6
 72
hr
 1235 1623 4056 0.4000 0.1719
MCF7 WYE-125132
0.04
uM
LJP6
 72
hr
 1235 1763 4056 0.4347 0.2305
MCF7 WYE-125132
0.12
uM
LJP6
 72
hr
 1235 1725 4056 0.4257 0.2153
MCF7 WYE-125132
0.37
uM
LJP6
 72
hr
 1235 1641 4056 0.4047 0.1801
MCF7 WYE-125132
1.11
uM
LJP6
 72
hr
 1235 1781 4056 0.4389 0.2365
MCF7 WYE-125132
3.33
uM
LJP6
 72
hr
 1235 1665 4056 0.4108 0.1905
MCF7 WYE-125132
10
uM
LJP6
 72
hr
 1235 1393 4056 0.3436 0.0728
MCF7 Barasertib
0.04
uM
LJP5
 72
hr
 1235 1732 4267 0.4070 0.2085
MCF7 Barasertib
0.12
uM
LJP5
 72
hr
 1235 1597 4267 0.3747 0.1549
MCF7 Barasertib
0.37
uM
LJP5
 72
hr
 1235 1618 4267 0.3795 0.1630
MCF7 Barasertib
1.11
uM
LJP5
 72
hr
 1235 1547 4267 0.3629 0.1343
MCF7 Barasertib
3.33
uM
LJP5
 72
hr
 1235 1601 4267 0.3757 0.1565