LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF7 Barasertib
10
uM
LJP5
 72
hr
 1235 1550 4267 0.3632 0.1348
MCF7 Vemurafenib
0.04
uM
LJP5
 72
hr
 1235 4219 4267 0.9908 0.9890
MCF7 Vemurafenib
0.12
uM
LJP5
 72
hr
 1235 4427 4267 1.0382 1.0428
MCF7 Vemurafenib
0.37
uM
LJP5
 72
hr
 1235 4319 4267 1.0135 1.0155
MCF7 Vemurafenib
1.11
uM
LJP5
 72
hr
 1235 4134 4267 0.9698 0.9664
MCF7 Vemurafenib
3.33
uM
LJP5
 72
hr
 1235 4159 4267 0.9760 0.9736
MCF7 Vemurafenib
10
uM
LJP5
 72
hr
 1235 3486 4267 0.8179 0.7876
MCF7 Enzastaurin
0.04
uM
LJP5
 72
hr
 1235 4036 4267 0.9475 0.9410
MCF7 Enzastaurin
0.12
uM
LJP5
 72
hr
 1235 4134 4267 0.9704 0.9669
MCF7 Enzastaurin
0.37
uM
LJP5
 72
hr
 1235 4352 4267 1.0209 1.0238
MCF7 Enzastaurin
1.11
uM
LJP5
 72
hr
 1235 3931 4267 0.9231 0.9119
MCF7 Enzastaurin
3.33
uM
LJP5
 72
hr
 1235 3734 4267 0.8768 0.8583
MCF7 Enzastaurin
10
uM
LJP5
 72
hr
 1235 2312 4267 0.5424 0.4204
MCF7 Palbociclib
0.04
uM
LJP6
 72
hr
 1235 3018 4056 0.7435 0.6816
MCF7 Palbociclib
0.12
uM
LJP6
 72
hr
 1235 2425 4056 0.5974 0.4803
MCF7 Palbociclib
0.37
uM
LJP6
 72
hr
 1235 2124 4056 0.5232 0.3697
MCF7 Palbociclib
1.11
uM
LJP6
 72
hr
 1235 1794 4056 0.4423 0.2429
MCF7 Palbociclib
3.33
uM
LJP6
 72
hr
 1235 1933 4056 0.4765 0.2981
MCF7 Palbociclib
10
uM
LJP6
 72
hr
 1235 1966 4056 0.4847 0.3111
MCF7 PF562271
0.04
uM
LJP6
 72
hr
 1235 3573 4056 0.8807 0.8566
MCF7 PF562271
0.12
uM
LJP6
 72
hr
 1235 3336 4056 0.8228 0.7851
MCF7 PF562271
0.37
uM
LJP6
 72
hr
 1235 2418 4056 0.5965 0.4794
MCF7 PF562271
1.11
uM
LJP6
 72
hr
 1235 1591 4056 0.3922 0.1581
MCF7 PF562271
3.33
uM
LJP6
 72
hr
 1235 986 4056 0.2430 -0.1235
MCF7 PF562271
10
uM
LJP6
 72
hr
 1235 725 4056 0.1788 -0.2674