LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
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MDA-MB-231 | PD0325901 | 0.12 | uM | LJP5 | 72 | hr | 868 | 1728 | 3486 | 0.4956 | 0.3284 |
MDA-MB-231 | PD0325901 | 0.12 | uM | LJP6 | 72 | hr | 868 | 1754 | 3486 | 0.5031 | 0.3383 |
MDA-MB-231 | PD173074 | 0.12 | uM | LJP6 | 72 | hr | 868 | 3919 | 3486 | 1.1241 | 1.1652 |
MDA-MB-231 | PD184352 | 0.12 | uM | LJP5 | 72 | hr | 868 | 2957 | 3486 | 0.8483 | 0.7979 |
MDA-MB-231 | Pelitinib | 0.12 | uM | LJP5 | 72 | hr | 868 | 3662 | 3486 | 1.0505 | 1.0672 |
MDA-MB-231 | PF431396 | 0.12 | uM | LJP5 | 72 | hr | 868 | 2949 | 3486 | 0.8459 | 0.7948 |
MDA-MB-231 | PF477736 | 0.12 | uM | LJP5 | 72 | hr | 868 | 3069 | 3486 | 0.8804 | 0.8407 |
MDA-MB-231 | PF562271 | 0.12 | uM | LJP6 | 72 | hr | 868 | 3076 | 3486 | 0.8824 | 0.8434 |
MDA-MB-231 | PHA-665752 | 0.12 | uM | LJP5 | 72 | hr | 868 | 3754 | 3486 | 1.0769 | 1.1023 |
MDA-MB-231 | PHA-793887 | 0.12 | uM | LJP6 | 72 | hr | 868 | 1159 | 3486 | 0.3325 | 0.1112 |
MDA-MB-231 | PI103 | 0.12 | uM | LJP6 | 72 | hr | 868 | 2455 | 3486 | 0.7042 | 0.6061 |
MDA-MB-231 | PLX-4720 | 0.12 | uM | LJP5 | 72 | hr | 868 | 3613 | 3486 | 1.0364 | 1.0485 |
MDA-MB-231 | QL-X-138 | 0.12 | uM | LJP6 | 72 | hr | 868 | 2753 | 3486 | 0.7896 | 0.7199 |
MDA-MB-231 | QL-XII-47 | 0.12 | uM | LJP6 | 72 | hr | 868 | 2063 | 3486 | 0.5919 | 0.4566 |
MDA-MB-231 | Radicicol | 0.12 | uM | LJP5 | 72 | hr | 868 | 2532 | 3486 | 0.7264 | 0.6357 |
MDA-MB-231 | Radicicol | 0.12 | uM | LJP6 | 72 | hr | 868 | 2529 | 3486 | 0.7255 | 0.6345 |
MDA-MB-231 | Seliciclib | 0.12 | uM | LJP5 | 72 | hr | 868 | 3379 | 3486 | 0.9693 | 0.9591 |
MDA-MB-231 | Ruxolitinib | 0.12 | uM | LJP5 | 72 | hr | 868 | 3094 | 3486 | 0.8875 | 0.8503 |
MDA-MB-231 | XL147 | 0.12 | uM | LJP5 | 72 | hr | 868 | 3671 | 3486 | 1.0531 | 1.0708 |
MDA-MB-231 | Saracatinib | 0.12 | uM | LJP6 | 72 | hr | 868 | 2848 | 3486 | 0.8169 | 0.7562 |
MDA-MB-231 | Selumetinib | 0.12 | uM | LJP6 | 72 | hr | 868 | 2519 | 3486 | 0.7227 | 0.6308 |
MDA-MB-231 | Sirolimus | 0.12 | uM | LJP6 | 72 | hr | 868 | 2728 | 3486 | 0.7826 | 0.7105 |
MDA-MB-231 | Sorafenib | 0.12 | uM | LJP6 | 72 | hr | 868 | 2798 | 3486 | 0.8027 | 0.7373 |
MDA-MB-231 | SU11274 | 0.12 | uM | LJP5 | 72 | hr | 868 | 3561 | 3486 | 1.0215 | 1.0286 |
MDA-MB-231 | Fedratinib | 0.12 | uM | LJP5 | 72 | hr | 868 | 3410 | 3486 | 0.9782 | 0.9710 |