LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 PD0325901
0.12
uM
LJP5
72
hr
868 1728 3486 0.4956 0.3284
MDA-MB-231 PD0325901
0.12
uM
LJP6
72
hr
868 1754 3486 0.5031 0.3383
MDA-MB-231 PD173074
0.12
uM
LJP6
72
hr
868 3919 3486 1.1241 1.1652
MDA-MB-231 PD184352
0.12
uM
LJP5
72
hr
868 2957 3486 0.8483 0.7979
MDA-MB-231 Pelitinib
0.12
uM
LJP5
72
hr
868 3662 3486 1.0505 1.0672
MDA-MB-231 PF431396
0.12
uM
LJP5
72
hr
868 2949 3486 0.8459 0.7948
MDA-MB-231 PF477736
0.12
uM
LJP5
72
hr
868 3069 3486 0.8804 0.8407
MDA-MB-231 PF562271
0.12
uM
LJP6
72
hr
868 3076 3486 0.8824 0.8434
MDA-MB-231 PHA-665752
0.12
uM
LJP5
72
hr
868 3754 3486 1.0769 1.1023
MDA-MB-231 PHA-793887
0.12
uM
LJP6
72
hr
868 1159 3486 0.3325 0.1112
MDA-MB-231 PI103
0.12
uM
LJP6
72
hr
868 2455 3486 0.7042 0.6061
MDA-MB-231 PLX-4720
0.12
uM
LJP5
72
hr
868 3613 3486 1.0364 1.0485
MDA-MB-231 QL-X-138
0.12
uM
LJP6
72
hr
868 2753 3486 0.7896 0.7199
MDA-MB-231 QL-XII-47
0.12
uM
LJP6
72
hr
868 2063 3486 0.5919 0.4566
MDA-MB-231 Radicicol
0.12
uM
LJP5
72
hr
868 2532 3486 0.7264 0.6357
MDA-MB-231 Radicicol
0.12
uM
LJP6
72
hr
868 2529 3486 0.7255 0.6345
MDA-MB-231 Seliciclib
0.12
uM
LJP5
72
hr
868 3379 3486 0.9693 0.9591
MDA-MB-231 Ruxolitinib
0.12
uM
LJP5
72
hr
868 3094 3486 0.8875 0.8503
MDA-MB-231 XL147
0.12
uM
LJP5
72
hr
868 3671 3486 1.0531 1.0708
MDA-MB-231 Saracatinib
0.12
uM
LJP6
72
hr
868 2848 3486 0.8169 0.7562
MDA-MB-231 Selumetinib
0.12
uM
LJP6
72
hr
868 2519 3486 0.7227 0.6308
MDA-MB-231 Sirolimus
0.12
uM
LJP6
72
hr
868 2728 3486 0.7826 0.7105
MDA-MB-231 Sorafenib
0.12
uM
LJP6
72
hr
868 2798 3486 0.8027 0.7373
MDA-MB-231 SU11274
0.12
uM
LJP5
72
hr
868 3561 3486 1.0215 1.0286
MDA-MB-231 Fedratinib
0.12
uM
LJP5
72
hr
868 3410 3486 0.9782 0.9710