LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | GW843682X | 10.0 | uM | LJP6 | 72 | hr | 1235 | 1612 | 4156 | 0.3880 | 0.1292 |
| MCF7 | HG-5-113-01 | 10.0 | uM | LJP5 | 72 | hr | 1235 | 883 | 4156 | 0.2125 | -0.1207 |
| MCF7 | HG-5-88-01 | 10.0 | uM | LJP6 | 72 | hr | 1235 | 1192 | 4156 | 0.2868 | -0.0149 |
| MCF7 | Imatinib | 10.0 | uM | LJP6 | 72 | hr | 1235 | 3826 | 4156 | 0.9206 | 0.8870 |
| MCF7 | JNK-9L | 10.0 | uM | LJP6 | 72 | hr | 1235 | 944 | 4156 | 0.2271 | -0.0998 |
| MCF7 | JW-7-24-1 | 10.0 | uM | LJP6 | 72 | hr | 1235 | 962 | 4156 | 0.2316 | -0.0934 |
| MCF7 | Lapatinib | 10.0 | uM | LJP6 | 72 | hr | 1235 | 2264 | 4156 | 0.5448 | 0.3523 |
| MCF7 | LDN-193189 | 10.0 | uM | LJP5 | 72 | hr | 1235 | 573 | 4156 | 0.1379 | -0.2268 |
| MCF7 | Linifanib | 10.0 | uM | LJP6 | 72 | hr | 1235 | 1365 | 4156 | 0.3284 | 0.0444 |
| MCF7 | Linsitinib | 10.0 | uM | LJP5 | 72 | hr | 1235 | 1868 | 4156 | 0.4495 | 0.2167 |
| MCF7 | Mitoxantrone | 10.0 | uM | LJP5 | 72 | hr | 1235 | 420 | 4156 | 0.1011 | -0.2791 |
| MCF7 | Mitoxantrone | 10.0 | uM | LJP6 | 72 | hr | 1235 | 408 | 4156 | 0.0982 | -0.2833 |
| MCF7 | MK2206 | 10.0 | uM | LJP6 | 72 | hr | 1235 | 733 | 4156 | 0.1764 | -0.1719 |
| MCF7 | Neratinib | 10.0 | uM | LJP5 | 72 | hr | 1235 | 1169 | 4156 | 0.2813 | -0.0227 |
| MCF7 | Nilotinib | 10.0 | uM | LJP5 | 72 | hr | 1235 | 1633 | 4156 | 0.3930 | 0.1363 |
| MCF7 | Nintedanib | 10.0 | uM | LJP6 | 72 | hr | 1235 | 844 | 4156 | 0.2032 | -0.1339 |
| MCF7 | NU7441 | 10.0 | uM | LJP5 | 72 | hr | 1235 | 1574 | 4156 | 0.3788 | 0.1161 |
| MCF7 | Dactolisib | 10.0 | uM | LJP5 | 72 | hr | 1235 | 1328 | 4156 | 0.3196 | 0.0318 |
| MCF7 | NVP-TAE684 | 10.0 | uM | LJP6 | 72 | hr | 1235 | 1168 | 4156 | 0.2812 | -0.0228 |
| MCF7 | Palbociclib | 10.0 | uM | LJP6 | 72 | hr | 1235 | 1966 | 4156 | 0.4732 | 0.2504 |
| MCF7 | PD0325901 | 10.0 | uM | LJP5 | 72 | hr | 1235 | 1168 | 4156 | 0.2811 | -0.0230 |
| MCF7 | PD0325901 | 10.0 | uM | LJP6 | 72 | hr | 1235 | 1104 | 4156 | 0.2658 | -0.0448 |
| MCF7 | PD173074 | 10.0 | uM | LJP6 | 72 | hr | 1235 | 3129 | 4156 | 0.7530 | 0.6486 |
| MCF7 | PD184352 | 10.0 | uM | LJP5 | 72 | hr | 1235 | 2074 | 4156 | 0.4990 | 0.2871 |
| MCF7 | Pelitinib | 10.0 | uM | LJP5 | 72 | hr | 1235 | 1082 | 4156 | 0.2604 | -0.0524 |