LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Canertinib | 10.0 | uM | LJP6 | 72 | hr | 1235 | 430 | 4156 | 0.1035 | -0.2756 |
| MCF7 | Celastrol | 10.0 | uM | LJP6 | 72 | hr | 1235 | 1051 | 4156 | 0.2529 | -0.0631 |
| MCF7 | CGP60474 | 10.0 | uM | LJP5 | 72 | hr | 1235 | 670 | 4156 | 0.1613 | -0.1935 |
| MCF7 | CGP60474 | 10.0 | uM | LJP6 | 72 | hr | 1235 | 383 | 4156 | 0.0922 | -0.2917 |
| MCF7 | CHIR-99021 | 10.0 | uM | LJP6 | 72 | hr | 1235 | 1624 | 4156 | 0.3907 | 0.1331 |
| MCF7 | CP724714 | 10.0 | uM | LJP5 | 72 | hr | 1235 | 2110 | 4156 | 0.5078 | 0.2996 |
| MCF7 | CP466722 | 10.0 | uM | LJP5 | 72 | hr | 1235 | 1972 | 4156 | 0.4745 | 0.2522 |
| MCF7 | Crizotinib | 10.0 | uM | LJP5 | 72 | hr | 1235 | 750 | 4156 | 0.1805 | -0.1662 |
| MCF7 | Momelotinib | 10.0 | uM | LJP5 | 72 | hr | 1235 | 1411 | 4156 | 0.3396 | 0.0602 |
| MCF7 | Dasatinib | 10.0 | uM | LJP5 | 72 | hr | 1235 | 918 | 4156 | 0.2210 | -0.1086 |
| MCF7 | Dasatinib | 10.0 | uM | LJP6 | 72 | hr | 1235 | 786 | 4156 | 0.1892 | -0.1537 |
| MCF7 | Dovitinib | 10.0 | uM | LJP5 | 72 | hr | 1235 | 2197 | 4156 | 0.5286 | 0.3292 |
| MCF7 | Enzastaurin | 10.0 | uM | LJP5 | 72 | hr | 1235 | 2312 | 4156 | 0.5564 | 0.3687 |
| MCF7 | Erlotinib | 10.0 | uM | LJP5 | 72 | hr | 1235 | 4268 | 4156 | 1.0270 | 1.0384 |
| MCF7 | Foretinib | 10.0 | uM | LJP5 | 72 | hr | 1235 | 839 | 4156 | 0.2020 | -0.1355 |
| MCF7 | R406 | 10.0 | uM | LJP6 | 72 | hr | 1235 | 1756 | 4156 | 0.4226 | 0.1784 |
| MCF7 | Pictilisib | 10.0 | uM | LJP6 | 72 | hr | 1235 | 1193 | 4156 | 0.2871 | -0.0144 |
| MCF7 | Gefitinib | 10.0 | uM | LJP6 | 72 | hr | 1235 | 3444 | 4156 | 0.8287 | 0.7563 |
| MCF7 | Geldanamycin | 10.0 | uM | LJP5 | 72 | hr | 1235 | 525 | 4156 | 0.1265 | -0.2430 |
| MCF7 | Geldanamycin | 10.0 | uM | LJP6 | 72 | hr | 1235 | 552 | 4156 | 0.1330 | -0.2338 |
| MCF7 | GSK1059615 | 10.0 | uM | LJP5 | 72 | hr | 1235 | 768 | 4156 | 0.1850 | -0.1598 |
| MCF7 | GSK1059615 | 10.0 | uM | LJP6 | 72 | hr | 1235 | 724 | 4156 | 0.1742 | -0.1751 |
| MCF7 | GSK1904529A | 10.0 | uM | LJP6 | 72 | hr | 1235 | 1742 | 4156 | 0.4193 | 0.1737 |
| MCF7 | Omipalisib | 10.0 | uM | LJP6 | 72 | hr | 1235 | 822 | 4156 | 0.1979 | -0.1413 |
| MCF7 | GSK 690693 | 10.0 | uM | LJP5 | 72 | hr | 1235 | 2142 | 4156 | 0.5155 | 0.3106 |