LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | AZD-6482 | 10.0 | uM | LJP5 | 72 | hr | 1235 | 1087 | 4156 | 0.2615 | -0.0508 |
| MCF7 | AZD7762 | 10.0 | uM | LJP6 | 72 | hr | 1235 | 765 | 4156 | 0.1842 | -0.1608 |
| MCF7 | AZD8055 | 10.0 | uM | LJP6 | 72 | hr | 1235 | 1116 | 4156 | 0.2686 | -0.0408 |
| MCF7 | AZD8330 | 10.0 | uM | LJP5 | 72 | hr | 1235 | 2532 | 4156 | 0.6092 | 0.4439 |
| MCF7 | Barasertib | 10.0 | uM | LJP5 | 72 | hr | 1235 | 1550 | 4156 | 0.3729 | 0.1077 |
| MCF7 | BI-2536 | 10.0 | uM | LJP6 | 72 | hr | 1235 | 934 | 4156 | 0.2248 | -0.1031 |
| MCF7 | BMS345541 | 10.0 | uM | LJP6 | 72 | hr | 1235 | 866 | 4156 | 0.2084 | -0.1265 |
| MCF7 | SNS-032 | 10.0 | uM | LJP6 | 72 | hr | 1235 | 598 | 4156 | 0.1440 | -0.2180 |
| MCF7 | GDC-0980 | 10.0 | uM | LJP5 | 72 | hr | 1235 | 1103 | 4156 | 0.2655 | -0.0452 |
| MCF7 | NVP-AEW541 | 10.0 | uM | LJP5 | 72 | hr | 1235 | 1048 | 4156 | 0.2522 | -0.0642 |
| MCF7 | SB590885 | 10.0 | uM | LJP5 | 72 | hr | 1235 | 2702 | 4156 | 0.6501 | 0.5021 |
| MCF7 | PIK-93 | 10.0 | uM | LJP5 | 72 | hr | 1235 | 1417 | 4156 | 0.3411 | 0.0624 |
| MCF7 | KIN001-043 | 10.0 | uM | LJP6 | 72 | hr | 1235 | 1765 | 4156 | 0.4247 | 0.1813 |
| MCF7 | Alpelisib | 10.0 | uM | LJP5 | 72 | hr | 1235 | 1043 | 4156 | 0.2511 | -0.0656 |
| MCF7 | Luminespib | 10.0 | uM | LJP5 | 72 | hr | 1235 | 1233 | 4156 | 0.2967 | -0.0008 |
| MCF7 | A443654 | 10.0 | uM | LJP6 | 72 | hr | 1235 | 748 | 4156 | 0.1801 | -0.1666 |
| MCF7 | OSI-027 | 10.0 | uM | LJP6 | 72 | hr | 1235 | 1623 | 4156 | 0.3907 | 0.1329 |
| MCF7 | XMD11-85h | 10.0 | uM | LJP6 | 72 | hr | 1235 | 1983 | 4156 | 0.4771 | 0.2560 |
| MCF7 | HG-6-64-01 | 10.0 | uM | LJP6 | 72 | hr | 1235 | 701 | 4156 | 0.1688 | -0.1827 |
| MCF7 | WH-4-025 | 10.0 | uM | LJP5 | 72 | hr | 1235 | 1043 | 4156 | 0.2511 | -0.0656 |
| MCF7 | WZ-4-145 | 10.0 | uM | LJP6 | 72 | hr | 1235 | 895 | 4156 | 0.2155 | -0.1163 |
| MCF7 | XMD16-144 | 10.0 | uM | LJP5 | 72 | hr | 1235 | 732 | 4156 | 0.1763 | -0.1721 |
| MCF7 | Brivanib | 10.0 | uM | LJP5 | 72 | hr | 1235 | 3638 | 4156 | 0.8755 | 0.8228 |
| MCF7 | Buparlisib | 10.0 | uM | LJP5 | 72 | hr | 1235 | 873 | 4156 | 0.2102 | -0.1238 |
| MCF7 | BX-912 | 10.0 | uM | LJP5 | 72 | hr | 1235 | 1281 | 4156 | 0.3082 | 0.0156 |