LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 GSK1059615
0.12
uM
LJP5
 72
hr
 868 3699 3486 1.0612 1.0815
MDA-MB-231 GSK1059615
0.12
uM
LJP6
 72
hr
 868 3571 3486 1.0245 1.0326
MDA-MB-231 GSK1904529A
0.12
uM
LJP6
 72
hr
 868 2916 3486 0.8366 0.7824
MDA-MB-231 Omipalisib
0.12
uM
LJP6
 72
hr
 868 1578 3486 0.4527 0.2713
MDA-MB-231 GSK 690693
0.12
uM
LJP5
 72
hr
 868 3040 3486 0.8722 0.8298
MDA-MB-231 GW843682X
0.12
uM
LJP6
 72
hr
 868 2574 3486 0.7383 0.6515
MDA-MB-231 HG-5-113-01
0.12
uM
LJP5
 72
hr
 868 2837 3486 0.8139 0.7522
MDA-MB-231 HG-5-88-01
0.12
uM
LJP6
 72
hr
 868 2640 3486 0.7574 0.6770
MDA-MB-231 Imatinib
0.12
uM
LJP6
 72
hr
 868 3686 3486 1.0573 1.0764
MDA-MB-231 JNK-9L
0.12
uM
LJP6
 72
hr
 868 2466 3486 0.7073 0.6103
MDA-MB-231 JW-7-24-1
0.12
uM
LJP6
 72
hr
 868 2730 3486 0.7832 0.7114
MDA-MB-231 Lapatinib
0.12
uM
LJP6
 72
hr
 868 3327 3486 0.9544 0.9393
MDA-MB-231 LDN-193189
0.12
uM
LJP5
 72
hr
 868 3525 3486 1.0111 1.0147
MDA-MB-231 Linifanib
0.12
uM
LJP6
 72
hr
 868 4002 3486 1.1481 1.1972
MDA-MB-231 Linsitinib
0.12
uM
LJP5
 72
hr
 868 2755 3486 0.7902 0.7207
MDA-MB-231 Mitoxantrone
0.12
uM
LJP5
 72
hr
 868 928 3486 0.2662 0.0229
MDA-MB-231 Mitoxantrone
0.12
uM
LJP6
 72
hr
 868 882 3486 0.2531 0.0054
MDA-MB-231 MK2206
0.12
uM
LJP6
 72
hr
 868 3092 3486 0.8869 0.8494
MDA-MB-231 Neratinib
0.12
uM
LJP5
 72
hr
 868 2454 3486 0.7041 0.6060
MDA-MB-231 Nilotinib
0.12
uM
LJP5
 72
hr
 868 2785 3486 0.7990 0.7324
MDA-MB-231 Nintedanib
0.12
uM
LJP6
 72
hr
 868 3640 3486 1.0442 1.0589
MDA-MB-231 NU7441
0.12
uM
LJP5
 72
hr
 868 3276 3486 0.9397 0.9196
MDA-MB-231 Dactolisib
0.12
uM
LJP5
 72
hr
 868 1811 3486 0.5195 0.3602
MDA-MB-231 NVP-TAE684
0.12
uM
LJP6
 72
hr
 868 2310 3486 0.6628 0.5510
MDA-MB-231 Palbociclib
0.12
uM
LJP6
 72
hr
 868 2338 3486 0.6707 0.5615