LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 TGX221
0.12
uM
LJP5
 72
hr
 868 2538 3486 0.7282 0.6380
MDA-MB-231 Torin1
0.12
uM
LJP6
 72
hr
 868 1718 3486 0.4928 0.3246
MDA-MB-231 Torin2
0.12
uM
LJP5
 72
hr
 868 1153 3486 0.3309 0.1091
MDA-MB-231 Tozasertib
0.12
uM
LJP5
 72
hr
 868 1063 3486 0.3051 0.0747
MDA-MB-231 Trametinib
0.12
uM
LJP5
 72
hr
 868 1278 3486 0.3668 0.1568
MDA-MB-231 TWS119
0.12
uM
LJP5
 72
hr
 868 3524 3486 1.0108 1.0144
MDA-MB-231 Vemurafenib
0.12
uM
LJP5
 72
hr
 868 3233 3486 0.9274 0.9034
MDA-MB-231 Withaferin A
0.12
uM
LJP5
 72
hr
 868 3622 3486 1.0389 1.0518
MDA-MB-231 Withaferin A
0.12
uM
LJP6
 72
hr
 868 3540 3486 1.0155 1.0206
MDA-MB-231 WYE-125132
0.12
uM
LJP6
 72
hr
 868 2075 3486 0.5952 0.4609
MDA-MB-231 WZ3105
0.12
uM
LJP5
 72
hr
 868 716 3486 0.2056 -0.0578
MDA-MB-231 XMD11-50
0.12
uM
LJP6
 72
hr
 868 2910 3486 0.8347 0.7799
MDA-MB-231 Y39983
0.12
uM
LJP6
 72
hr
 868 3097 3486 0.8884 0.8514
MDA-MB-231 YM 201636
0.12
uM
LJP5
 72
hr
 868 3322 3486 0.9529 0.9373
MDA-MB-231 ZSTK474
0.12
uM
LJP6
 72
hr
 868 3136 3486 0.8995 0.8662
MDA-MB-231 Afatinib
0.37
uM
LJP6
 72
hr
 868 2774 3486 0.7957 0.7279
MDA-MB-231 Sigma A6730
0.37
uM
LJP5
 72
hr
 868 2971 3486 0.8523 0.8033
MDA-MB-231 Alvocidib
0.37
uM
LJP6
 72
hr
 868 611 3486 0.1753 -0.0982
MDA-MB-231 AT-7519
0.37
uM
LJP6
 72
hr
 868 965 3486 0.2768 0.0370
MDA-MB-231 AZD 5438
0.37
uM
LJP6
 72
hr
 868 1651 3486 0.4737 0.2991
MDA-MB-231 AZD-6482
0.37
uM
LJP5
 72
hr
 868 3027 3486 0.8682 0.8245
MDA-MB-231 AZD7762
0.37
uM
LJP6
 72
hr
 868 1351 3486 0.3876 0.1846
MDA-MB-231 AZD8055
0.37
uM
LJP6
 72
hr
 868 1365 3486 0.3915 0.1898
MDA-MB-231 AZD8330
0.37
uM
LJP5
 72
hr
 868 919 3486 0.2637 0.0196
MDA-MB-231 Barasertib
0.37
uM
LJP5
 72
hr
 868 1244 3486 0.3570 0.1438