LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 AZD-6482
3.33
uM
LJP5
 72
hr
 868 1993 3486 0.5718 0.4299
MDA-MB-231 AZD7762
3.33
uM
LJP6
 72
hr
 868 683 3486 0.1959 -0.0707
MDA-MB-231 AZD8055
3.33
uM
LJP6
 72
hr
 868 1260 3486 0.3616 0.1499
MDA-MB-231 AZD8330
3.33
uM
LJP5
 72
hr
 868 974 3486 0.2794 0.0404
MDA-MB-231 Barasertib
3.33
uM
LJP5
 72
hr
 868 1209 3486 0.3469 0.1303
MDA-MB-231 BI-2536
3.33
uM
LJP6
 72
hr
 868 1170 3486 0.3358 0.1156
MDA-MB-231 BMS345541
3.33
uM
LJP6
 72
hr
 868 1189 3486 0.3412 0.1228
MDA-MB-231 SNS-032
3.33
uM
LJP6
 72
hr
 868 847 3486 0.2429 -0.0081
MDA-MB-231 GDC-0980
3.33
uM
LJP5
 72
hr
 868 1526 3486 0.4377 0.2513
MDA-MB-231 NVP-AEW541
3.33
uM
LJP5
 72
hr
 868 3380 3486 0.9695 0.9594
MDA-MB-231 SB590885
3.33
uM
LJP5
 72
hr
 868 1920 3486 0.5508 0.4019
MDA-MB-231 PIK-93
3.33
uM
LJP5
 72
hr
 868 2602 3486 0.7463 0.6622
MDA-MB-231 KIN001-043
3.33
uM
LJP6
 72
hr
 868 3346 3486 0.9598 0.9465
MDA-MB-231 Alpelisib
3.33
uM
LJP5
 72
hr
 868 3000 3486 0.8606 0.8144
MDA-MB-231 Luminespib
3.33
uM
LJP5
 72
hr
 868 1007 3486 0.2889 0.0532
MDA-MB-231 A443654
3.33
uM
LJP6
 72
hr
 868 572 3486 0.1641 -0.1131
MDA-MB-231 OSI-027
3.33
uM
LJP6
 72
hr
 868 2262 3486 0.6490 0.5326
MDA-MB-231 XMD11-85h
3.33
uM
LJP6
 72
hr
 868 2457 3486 0.7047 0.6068
MDA-MB-231 HG-6-64-01
3.33
uM
LJP6
 72
hr
 868 1045 3486 0.2997 0.0676
MDA-MB-231 WH-4-025
3.33
uM
LJP5
 72
hr
 868 811 3486 0.2327 -0.0217
MDA-MB-231 WZ-4-145
3.33
uM
LJP6
 72
hr
 868 2538 3486 0.7282 0.6380
MDA-MB-231 XMD16-144
3.33
uM
LJP5
 72
hr
 868 1251 3486 0.3590 0.1465
MDA-MB-231 Brivanib
3.33
uM
LJP5
 72
hr
 868 2782 3486 0.7982 0.7312
MDA-MB-231 Buparlisib
3.33
uM
LJP5
 72
hr
 868 1135 3486 0.3257 0.1021
MDA-MB-231 BX-912
3.33
uM
LJP5
 72
hr
 868 1451 3486 0.4163 0.2228