Ibrutinib KiNativ -- single dose experiment - Dataset (ID:20214)
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| Small Molecule | Cell Line | Protein | Sequence | Labeling Site | % Inhibition | Assay compound conc | Conc unit |
|---|---|---|---|---|---|---|---|
| Ibrutinib | MWCL.1 | ABL,ARG | LMTGDTYTAHAGAKFPIK | Activation Loop | 21.72837795 | 1 | uM |
| Ibrutinib | MWCL.1 | ABL,ARG | YSLTVAVKTLKEDTMEVEEFLK | Lys1 | 12.59371135 | 1 | uM |
| Ibrutinib | MWCL.1 | ACK | TVSVAVKCLKPDVLSQPEAMDDFIR | Lys1 | -6.080132345 | 1 | uM |
| Ibrutinib | MWCL.1 | AMPKa1,AMPKa2 | DLKPENVLLDAHMNAK | Lys2 | -20.41222341 | 1 | uM |
| Ibrutinib | MWCL.1 | ARAF | DLKSNNIFLHEGLTVK | Lys2 | 22.16700729 | 1 | uM |
| Ibrutinib | MWCL.1 | ATR | FYIMMCKPK | ATP | -33.39274836 | 1 | uM |
| Ibrutinib | MWCL.1 | AurA | FILALKVLFK | Lys1 | 2.631575746 | 1 | uM |
| Ibrutinib | MWCL.1 | AurB | SHFIVALKVLFK | Lys1 | -4.958760656 | 1 | uM |
| Ibrutinib | MWCL.1 | BARK1 | DLKPANILLDEHGHVR | Lys2 | 12.03792468 | 1 | uM |
| Ibrutinib | MWCL.1 | BRAF | DLKSNNIFLHEDLTVK | Lys2 | -0.793785523 | 1 | uM |
| Ibrutinib | MWCL.1 | BTK | YVLDDEYTSSVGSKFPVR | Activation Loop | 99.03862673 | 1 | uM |
| Ibrutinib | MWCL.1 | CAMK1D | LFAVKCIPK | Lys1 | -6.007350223 | 1 | uM |
| Ibrutinib | MWCL.1 | CaMK2g | TSTQEYAAKIINTK | Lys1 | -5.159231787 | 1 | uM |
| Ibrutinib | MWCL.1 | CaMKK2 | DIKPSNLLVGEDGHIK | Lys2 | -3.023136542 | 1 | uM |
| Ibrutinib | MWCL.1 | CASK | ETGQQFAVKIVDVAK | Lys1 | 21.2690292 | 1 | uM |
| Ibrutinib | MWCL.1 | CDC2 | DLKPQNLLIDDKGTIK | Lys2 | 4.72216791 | 1 | uM |
| Ibrutinib | MWCL.1 | CDK11,CDK8 | DLKPANILVMGEGPER | Lys2 | -25.79545872 | 1 | uM |
| Ibrutinib | MWCL.1 | CDK2 | DLKPQNLLINTEGAIK | Lys2 | -0.986909811 | 1 | uM |
| Ibrutinib | MWCL.1 | CDK4 | DLKPENILVTSGGTVK | Lys2 | -5.399760136 | 1 | uM |
| Ibrutinib | MWCL.1 | CDK5 | DLKPQNLLINR | Lys2 | -10.15079399 | 1 | uM |
| Ibrutinib | MWCL.1 | CDK6 | DLKPQNILVTSSGQIK | Lys2 | 7.22720664 | 1 | uM |
| Ibrutinib | MWCL.1 | CDK7 | DLKPNNLLLDENGVLK | Lys2 | 2.518030866 | 1 | uM |
| Ibrutinib | MWCL.1 | CDK9 | DMKAANVLITR | Lys2 | -11.45632037 | 1 | uM |
| Ibrutinib | MWCL.1 | CHK1 | DIKPENLLLDER | Lys2 | 15.77072939 | 1 | uM |
| Ibrutinib | MWCL.1 | CHK2 | DLKPENVLLSSQEEDCLIK | Lys2 | 10.99801582 | 1 | uM |