Ibrutinib KiNativ -- single dose experiment - Dataset (ID:20214)
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| Small Molecule | Cell Line | Protein | Sequence | Labeling Site | % Inhibition | Assay compound conc | Conc unit |
|---|---|---|---|---|---|---|---|
| Ibrutinib | BCWM.1 | BTK | YVLDDEYTSSVGSKFPVR | Activation Loop | 97.34431584 | 1 | uM |
| Ibrutinib | BCWM.1 | KSR1,KSR2 | SKNVFYDNGK | Activation Loop | 10.93063105 | 1 | uM |
| Ibrutinib | MWCL.1 | SYK | ISDFGLSKALR | Activation Loop | 5.294162573 | 1 | uM |
| Ibrutinib | BCWM.1 | ABL,ARG | LMTGDTYTAHAGAKFPIK | Activation Loop | 0.604314574 | 1 | uM |
| Ibrutinib | BCWM.1 | FGR | LIKDDEYNPCQGSKFPIK | Activation Loop | 73.81381667 | 1 | uM |
| Ibrutinib | BCWM.1 | JAK3 domain2 | IADFGLAKLLPLDKDYYVVR | Activation Loop | 35.44676685 | 1 | uM |
| Ibrutinib | MWCL.1 | FYN,SRC,YES | QGAKFPIKWTAPEAALYGR | Activation Loop | 67.06910559 | 1 | uM |
| Ibrutinib | MWCL.1 | STLK5 | YSVKVLPWLSPEVLQQNLQGYDAK | Activation Loop | -1.817329189 | 1 | uM |
| Ibrutinib | MWCL.1 | TEC | YVLDDQYTSSSGAKFPVK | Activation Loop | > 95 | 1 | uM |
| Ibrutinib | MWCL.1 | JAK1_domain2 | IGDFGLTKAIETDKEYYTVK | Activation Loop | -1.182963279 | 1 | uM |
| Ibrutinib | BCWM.1 | EPHB2 | FLEDDTSDPTYTSALGGKIPIR | Activation Loop | -13.84359152 | 1 | uM |
| Ibrutinib | MWCL.1 | NEK3 | SKNIFLTQNGK | Activation Loop | 7.904108301 | 1 | uM |
| Ibrutinib | BCWM.1 | FYN,SRC,YES | QGAKFPIKWTAPEAALYGR | Activation Loop | 22.58878067 | 1 | uM |
| Ibrutinib | BCWM.1 | JAK1_domain2 | IGDFGLTKAIETDKEYYTVK | Activation Loop | 24.89996943 | 1 | uM |
| Ibrutinib | MWCL.1 | ABL,ARG | LMTGDTYTAHAGAKFPIK | Activation Loop | 21.72837795 | 1 | uM |
| Ibrutinib | MWCL.1 | CSK | VSDFGLTKEASSTQDTGKLPVK | Activation Loop | 50.62489805 | 1 | uM |
| Ibrutinib | MWCL.1 | KSR1,KSR2 | SKNVFYDNGK | Activation Loop | -0.502681471 | 1 | uM |
| Ibrutinib | MWCL.1 | FAK2 | YIEDEDYYKASVTR | Activation Loop | -32.32583925 | 1 | uM |
| Ibrutinib | MWCL.1 | JAK3 domain2 | IADFGLAKLLPLDKDYYVVR | Activation Loop | -18.73992925 | 1 | uM |
| Ibrutinib | MWCL.1 | EPHB2 | FLEDDTSDPTYTSALGGKIPIR | Activation Loop | ND | 1 | uM |
| Ibrutinib | MWCL.1 | BTK | YVLDDEYTSSVGSKFPVR | Activation Loop | 99.03862673 | 1 | uM |
| Ibrutinib | MWCL.1 | FGR | LIKDDEYNPCQGSKFPIK | Activation Loop | 92.01632306 | 1 | uM |
| Ibrutinib | BCWM.1 | CSK | VSDFGLTKEASSTQDTGKLPVK | Activation Loop | 15.82121782 | 1 | uM |
| Ibrutinib | BCWM.1 | FAK2 | YIEDEDYYKASVTR | Activation Loop | 5.185805758 | 1 | uM |
| Ibrutinib | BCWM.1 | NEK3 | SKNIFLTQNGK | Activation Loop | -12.44583296 | 1 | uM |