Ibrutinib KiNativ -- single dose experiment - Dataset (ID:20214)
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| Small Molecule | Cell Line | Protein | Sequence | Labeling Site | % Inhibition | Assay compound conc | Conc unit |
|---|---|---|---|---|---|---|---|
| Ibrutinib | BCWM.1 | KSR1 | SKNVFYDNGKVVITDFGLFGISGVVR | Activation Loop | -0.005640215 | 1 | uM |
| Ibrutinib | BCWM.1 | CDK2 | DLKPQNLLINTEGAIK | Lys2 | -0.014042983 | 1 | uM |
| Ibrutinib | BCWM.1 | ULK3 | NISHLDLKPQNILLSSLEKPHLK | Lys2 | -0.055167396 | 1 | uM |
| Ibrutinib | MWCL.1 | SMG1 | DTVTIHSVGGTITILPTKTKPK | ATP | 0.095784852 | 1 | uM |
| Ibrutinib | BCWM.1 | ARAF | DLKSNNIFLHEGLTVK | Lys2 | 0.09851812 | 1 | uM |
| Ibrutinib | MWCL.1 | NEK9 | DIKTLNIFLTK | Lys2 | -0.237961412 | 1 | uM |
| Ibrutinib | BCWM.1 | IKKA | DLKPENIVLQDVGGK | Lys2 | -0.304730196 | 1 | uM |
| Ibrutinib | MWCL.1 | MYO3A,MYO3B | DVKGNNILLTTEGGVK | Lys2 | -0.322018507 | 1 | uM |
| Ibrutinib | BCWM.1 | MST2 | ESGQVVAIKQVPVESDLQEIIK | Lys1 | 0.3625671 | 1 | uM |
| Ibrutinib | BCWM.1 | MK11 | QELNKTVWEVPQR | Other | -0.386101983 | 1 | uM |
| Ibrutinib | MWCL.1 | MAP2K6 | DVKPSNVLINALGQVK | Lys2 | 0.432117988 | 1 | uM |
| Ibrutinib | BCWM.1 | Wnk1,Wnk2,Wnk3 | DLKCDNIFITGPTGSVK | Lys2 | -0.449832509 | 1 | uM |
| Ibrutinib | MWCL.1 | MAP2K3 | DVKPSNVLINK | Lys2 | -0.499074082 | 1 | uM |
| Ibrutinib | MWCL.1 | KSR1,KSR2 | SKNVFYDNGK | Activation Loop | -0.502681471 | 1 | uM |
| Ibrutinib | BCWM.1 | LKB1 | DIKPGNLLLTTGGTLK | Lys2 | -0.513579966 | 1 | uM |
| Ibrutinib | BCWM.1 | ABL,ARG | LMTGDTYTAHAGAKFPIK | Activation Loop | 0.604314574 | 1 | uM |
| Ibrutinib | BCWM.1 | CASK | ETGQQFAVKIVDVAK | Lys1 | -0.612279673 | 1 | uM |
| Ibrutinib | BCWM.1 | CDK7 | DLKPNNLLLDENGVLK | Lys2 | 0.668563166 | 1 | uM |
| Ibrutinib | MWCL.1 | NEK2 | DLKPANVFLDGK | Lys2 | -0.76249132 | 1 | uM |
| Ibrutinib | MWCL.1 | PRPK | FLSGLELVKQGAEAR | ATP Loop | 0.793300257 | 1 | uM |
| Ibrutinib | MWCL.1 | BRAF | DLKSNNIFLHEDLTVK | Lys2 | -0.793785523 | 1 | uM |
| Ibrutinib | BCWM.1 | ULK1 | DLKPQNILLSNPAGR | Lys2 | -0.802332312 | 1 | uM |
| Ibrutinib | BCWM.1 | PITSLRE | DLKTSNLLLSHAGILK | Lys2 | 0.867558432 | 1 | uM |
| Ibrutinib | BCWM.1 | p38d,p38g | DLKPGNLAVNEDCELK | Lys2 | 0.981795646 | 1 | uM |
| Ibrutinib | MWCL.1 | CDK2 | DLKPQNLLINTEGAIK | Lys2 | -0.986909811 | 1 | uM |