Ibrutinib KiNativ -- single dose experiment - Dataset (ID:20214)
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| Small Molecule | Cell Line | Protein | Sequence | Labeling Site | % Inhibition | Assay compound conc | Conc unit |
|---|---|---|---|---|---|---|---|
| Ibrutinib | BCWM.1 | ABL,ARG | LMTGDTYTAHAGAKFPIK | Activation Loop | 0.604314574 | 1 | uM |
| Ibrutinib | MWCL.1 | ABL,ARG | YSLTVAVKTLKEDTMEVEEFLK | Lys1 | 12.59371135 | 1 | uM |
| Ibrutinib | MWCL.1 | ABL,ARG | LMTGDTYTAHAGAKFPIK | Activation Loop | 21.72837795 | 1 | uM |
| Ibrutinib | BCWM.1 | ABL,ARG | YSLTVAVKTLKEDTMEVEEFLK | Lys1 | -47.25685345 | 1 | uM |
| Ibrutinib | BCWM.1 | ACK | TVSVAVKCLKPDVLSQPEAMDDFIR | Lys1 | -31.80246763 | 1 | uM |
| Ibrutinib | MWCL.1 | ACK | TVSVAVKCLKPDVLSQPEAMDDFIR | Lys1 | -6.080132345 | 1 | uM |
| Ibrutinib | MWCL.1 | AMPKa1,AMPKa2 | DLKPENVLLDAHMNAK | Lys2 | -20.41222341 | 1 | uM |
| Ibrutinib | BCWM.1 | AMPKa1,AMPKa2 | DLKPENVLLDAHMNAK | Lys2 | -38.52805558 | 1 | uM |
| Ibrutinib | MWCL.1 | ARAF | DLKSNNIFLHEGLTVK | Lys2 | 22.16700729 | 1 | uM |
| Ibrutinib | BCWM.1 | ARAF | DLKSNNIFLHEGLTVK | Lys2 | 0.09851812 | 1 | uM |
| Ibrutinib | MWCL.1 | ATR | FYIMMCKPK | ATP | -33.39274836 | 1 | uM |
| Ibrutinib | BCWM.1 | ATR | FYIMMCKPK | ATP | -28.87734455 | 1 | uM |
| Ibrutinib | MWCL.1 | AurA | FILALKVLFK | Lys1 | 2.631575746 | 1 | uM |
| Ibrutinib | BCWM.1 | AurA | FILALKVLFK | Lys1 | 10.83507824 | 1 | uM |
| Ibrutinib | MWCL.1 | AurB | SHFIVALKVLFK | Lys1 | -4.958760656 | 1 | uM |
| Ibrutinib | BCWM.1 | AurB | SHFIVALKVLFK | Lys1 | 5.086064352 | 1 | uM |
| Ibrutinib | BCWM.1 | BARK1 | DLKPANILLDEHGHVR | Lys2 | -16.279379 | 1 | uM |
| Ibrutinib | MWCL.1 | BARK1 | DLKPANILLDEHGHVR | Lys2 | 12.03792468 | 1 | uM |
| Ibrutinib | BCWM.1 | BLK | IIDSEYTAQEGAKFPIK | Activation Loop | > 60 | 1 | uM |
| Ibrutinib | MWCL.1 | BLK | IIDSEYTAQEGAKFPIK | Activation Loop | ND | 1 | uM |
| Ibrutinib | BCWM.1 | BRAF | DLKSNNIFLHEDLTVK | Lys2 | -15.53527116 | 1 | uM |
| Ibrutinib | MWCL.1 | BRAF | DLKSNNIFLHEDLTVK | Lys2 | -0.793785523 | 1 | uM |
| Ibrutinib | MWCL.1 | BTK | YVLDDEYTSSVGSKFPVR | Activation Loop | 99.03862673 | 1 | uM |
| Ibrutinib | BCWM.1 | BTK | YVLDDEYTSSVGSKFPVR | Activation Loop | 97.34431584 | 1 | uM |
| Ibrutinib | BCWM.1 | CAMK1D | LFAVKCIPK | Lys1 | 9.317991024 | 1 | uM |