Ibrutinib KiNativ -- single dose experiment - Dataset (ID:20214)
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| Small Molecule | Cell Line | Protein | Sequence | Labeling Site | % Inhibition | Assay compound conc | Conc unit |
|---|---|---|---|---|---|---|---|
| Ibrutinib | MWCL.1 | ZC2/TNIK | TGQLAAIKVMDVTGDEEEEIKQEINMLKK | Lys1 | -11.51803213 | 1 | uM |
| Ibrutinib | BCWM.1 | ZC2/TNIK | TGQLAAIKVMDVTGDEEEEIKQEINMLKK | Lys1 | -51.1480675 | 1 | uM |
| Ibrutinib | MWCL.1 | ZC1/HGK,ZC2/TNIK,ZC3/MINK | DIKGQNVLLTENAEVK | Lys2 | -2.178793166 | 1 | uM |
| Ibrutinib | BCWM.1 | ZC1/HGK,ZC2/TNIK,ZC3/MINK | DIKGQNVLLTENAEVK | Lys2 | 5.566332997 | 1 | uM |
| Ibrutinib | BCWM.1 | Wnk1,Wnk2,Wnk3 | DLKCDNIFITGPTGSVK | Lys2 | -0.449832509 | 1 | uM |
| Ibrutinib | MWCL.1 | Wnk1,Wnk2,Wnk3 | DLKCDNIFITGPTGSVK | Lys2 | -21.21985149 | 1 | uM |
| Ibrutinib | BCWM.1 | Wnk1,Wnk2 | GSFKTVYK | ATP Loop | -10.02684253 | 1 | uM |
| Ibrutinib | MWCL.1 | Wnk1,Wnk2 | GSFKTVYK | ATP Loop | 6.431224998 | 1 | uM |
| Ibrutinib | BCWM.1 | WEE1 | YIHSMSLVHMDIKPSNIFISR | Lys2 | -66.07854902 | 1 | uM |
| Ibrutinib | MWCL.1 | WEE1 | YIHSMSLVHMDIKPSNIFISR | Lys2 | -33.51822992 | 1 | uM |
| Ibrutinib | BCWM.1 | VRK2 | MLDVLEYIHENEYVHGDIKAANLLLGYK | Lys2 | -13.00273003 | 1 | uM |
| Ibrutinib | MWCL.1 | VRK2 | MLDVLEYIHENEYVHGDIKAANLLLGYK | Lys2 | -8.993081564 | 1 | uM |
| Ibrutinib | BCWM.1 | ULK3 | NISHLDLKPQNILLSSLEKPHLK | Lys2 | -0.055167396 | 1 | uM |
| Ibrutinib | MWCL.1 | ULK3 | NISHLDLKPQNILLSSLEKPHLK | Lys2 | -18.27216024 | 1 | uM |
| Ibrutinib | BCWM.1 | ULK1 | DLKPQNILLSNPAGR | Lys2 | -0.802332312 | 1 | uM |
| Ibrutinib | MWCL.1 | ULK1 | DLKPQNILLSNPAGR | Lys2 | -3.373570817 | 1 | uM |
| Ibrutinib | BCWM.1 | TYK2(Kin.Dom.2) | IGDFGLAKAVPEGHEYYR | Activation Loop | 1.129238559 | 1 | uM |
| Ibrutinib | MWCL.1 | TYK2(Kin.Dom.2) | IGDFGLAKAVPEGHEYYR | Activation Loop | 1.07145223 | 1 | uM |
| Ibrutinib | MWCL.1 | TLK1/2 | YLNEIKPPIIHYDLKPGNILLVNGTACGEIK | Lys2 | 6.438215368 | 1 | uM |
| Ibrutinib | BCWM.1 | TLK1/2 | YLNEIKPPIIHYDLKPGNILLVNGTACGEIK | Lys2 | 11.88568593 | 1 | uM |
| Ibrutinib | BCWM.1 | TLK1 | YLNEIKPPIIHYDLKPGNILLVDGTACGEIK | Lys2 | 10.62242227 | 1 | uM |
| Ibrutinib | MWCL.1 | TLK1 | YLNEIKPPIIHYDLKPGNILLVDGTACGEIK | Lys2 | 4.10725124 | 1 | uM |
| Ibrutinib | BCWM.1 | TEC | YVLDDQYTSSSGAKFPVK | Activation Loop | > 87 | 1 | uM |
| Ibrutinib | MWCL.1 | TEC | YVLDDQYTSSSGAKFPVK | Activation Loop | > 95 | 1 | uM |
| Ibrutinib | MWCL.1 | TBK1 | TGDLFAIKVFNNISFLRPVDVQMR | Lys1 | -4.532128705 | 1 | uM |