Ibrutinib KiNativ -- single dose experiment - Dataset (ID:20214)
Download: Excel (XLSX), Comma-separated (CSV)
| Small Molecule | Cell Line | Protein | Sequence | Labeling Site | % Inhibition | Assay compound conc | Conc unit |
|---|---|---|---|---|---|---|---|
| Ibrutinib | MWCL.1 | KC1A | DIKPDNFLMGIGR | Lys2 | -13.06792823 | 1 | uM |
| Ibrutinib | MWCL.1 | CK2a2 | DVKPHNVMIDHQQK | Lys2 | -1.176113438 | 1 | uM |
| Ibrutinib | MWCL.1 | CSK | VSDFGLTKEASSTQDTGKLPVK | Activation Loop | 50.62489805 | 1 | uM |
| Ibrutinib | MWCL.1 | DGKA | IDPVPNTHPLLVFVNPKSGGK | ATP | 7.880559471 | 1 | uM |
| Ibrutinib | MWCL.1 | DNAPK | EHPFLVKGGEDLR | ATP | 9.762351306 | 1 | uM |
| Ibrutinib | MWCL.1 | DNAPK | KGGSWIQEINVAEK | ATP | -14.86551516 | 1 | uM |
| Ibrutinib | MWCL.1 | eEF2K | YIKYNSNSGFVR | ATP | -15.74314914 | 1 | uM |
| Ibrutinib | MWCL.1 | EPHB2 | FLEDDTSDPTYTSALGGKIPIR | Activation Loop | ND | 1 | uM |
| Ibrutinib | MWCL.1 | MK03 | DLKPSNLLINTTCDLK | Lys2 | -6.526093844 | 1 | uM |
| Ibrutinib | MWCL.1 | Erk5 | DLKPSNLLVNENCELK | Lys2 | -23.23952311 | 1 | uM |
| Ibrutinib | MWCL.1 | FER | TSVAVKTCKEDLPQELK | Lys1 | 6.463057421 | 1 | uM |
| Ibrutinib | MWCL.1 | FES | LRADNTLVAVKSCR | Lys1 | 7.005056892 | 1 | uM |
| Ibrutinib | MWCL.1 | FGR | LIKDDEYNPCQGSKFPIK | Activation Loop | 92.01632306 | 1 | uM |
| Ibrutinib | MWCL.1 | FRAP1 | IQSIAPSLQVITSKQRPR | ATP | 6.166540735 | 1 | uM |
| Ibrutinib | MWCL.1 | FYN,SRC,YES | QGAKFPIKWTAPEAALYGR | Activation Loop | 67.06910559 | 1 | uM |
| Ibrutinib | MWCL.1 | GCK | DIKGANLLLTLQGDVK | Lys2 | -14.65091229 | 1 | uM |
| Ibrutinib | MWCL.1 | GCN2_domain2 | DLKPVNIFLDSDDHVK | Lys2 | 2.161733572 | 1 | uM |
| Ibrutinib | MWCL.1 | GSK3A | DIKPQNLLVDPDTAVLK | Lys2 | -8.092252883 | 1 | uM |
| Ibrutinib | MWCL.1 | GSK3B | DIKPQNLLLDPDTAVLK | Lys2 | -8.216334308 | 1 | uM |
| Ibrutinib | MWCL.1 | HPK1 | DIKGANILINDAGEVR | Lys2 | -1.686208781 | 1 | uM |
| Ibrutinib | MWCL.1 | IKKA | DLKPENIVLQDVGGK | Lys2 | -1.784675507 | 1 | uM |
| Ibrutinib | MWCL.1 | IKKB | DLKPENIVLQQGEQR | Lys2 | 4.884085812 | 1 | uM |
| Ibrutinib | MWCL.1 | IKKE | SGELVAVKVFNTTSYLRPR | Lys1 | 5.294746223 | 1 | uM |
| Ibrutinib | MWCL.1 | ILK | WQGNDIVVKVLK | Lys1 | -9.860957935 | 1 | uM |
| Ibrutinib | MWCL.1 | IRAK1 | AIQFLHQDSPSLIHGDIKSSNVLLDER | Lys2 | 15.56395006 | 1 | uM |