Ibrutinib KiNativ -- single dose experiment - Dataset (ID:20214)
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| Small Molecule | Cell Line | Protein | Sequence | Labeling Site | % Inhibition | Assay compound conc | Conc unit |
|---|---|---|---|---|---|---|---|
| Ibrutinib | BCWM.1 | MARK3 | EVAIKIIDKTQLNPTSLQK | Lys1 | -11.94730376 | 1 | uM |
| Ibrutinib | BCWM.1 | MARK3,MARK4 | EVAIKIIDK | Lys1 | -23.83070328 | 1 | uM |
| Ibrutinib | BCWM.1 | MAST1,MAST2 | DLKPDNLLITSMGHIK | Lys2 | -14.88979109 | 1 | uM |
| Ibrutinib | BCWM.1 | MAST3 | DLKPDNLLITSLGHIK | Lys2 | 7.95713657 | 1 | uM |
| Ibrutinib | BCWM.1 | MASTL | GAFGKVYLGQK | ATP Loop | -2.701929419 | 1 | uM |
| Ibrutinib | BCWM.1 | MASTL | LYAVKVVK | Lys1 | 2.297148952 | 1 | uM |
| Ibrutinib | BCWM.1 | MLK3 | DLKSNNILLLQPIESDDMEHK | Lys2 | -22.45540747 | 1 | uM |
| Ibrutinib | BCWM.1 | MLK4 | DLKSSNILLLEK | Lys2 | 5.573785495 | 1 | uM |
| Ibrutinib | BCWM.1 | MLKL | APVAIKVFK | Lys1 | 6.564211837 | 1 | uM |
| Ibrutinib | BCWM.1 | MSK1_domain1 | DIKLENILLDSNGHVVLTDFGLSK | Lys2 | 24.89837907 | 1 | uM |
| Ibrutinib | BCWM.1 | MSK2 domain1 | DLKLENVLLDSEGHIVLTDFGLSK | Lys2 | 40.22148406 | 1 | uM |
| Ibrutinib | BCWM.1 | MST1 | ETGQIVAIKQVPVESDLQEIIK | Lys1 | 5.587276642 | 1 | uM |
| Ibrutinib | BCWM.1 | MST2 | ESGQVVAIKQVPVESDLQEIIK | Lys1 | 0.3625671 | 1 | uM |
| Ibrutinib | BCWM.1 | MST3 | DIKAANVLLSEHGEVK | Lys2 | -9.956864462 | 1 | uM |
| Ibrutinib | BCWM.1 | MST4 | TQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTK | Lys1 | -9.213100679 | 1 | uM |
| Ibrutinib | BCWM.1 | MST4,YSK1 | DIKAANVLLSEQGDVK | Lys2 | -6.360178382 | 1 | uM |
| Ibrutinib | BCWM.1 | MYO3A,MYO3B | DVKGNNILLTTEGGVK | Lys2 | 7.942997988 | 1 | uM |
| Ibrutinib | BCWM.1 | NDR1 | DIKPDNLLLDSK | Lys2 | -1.353280454 | 1 | uM |
| Ibrutinib | BCWM.1 | NDR2 | DIKPDNLLLDAK | Lys2 | 1.201292359 | 1 | uM |
| Ibrutinib | BCWM.1 | NEK1 | DIKSQNIFLTK | Lys2 | -2.29771958 | 1 | uM |
| Ibrutinib | BCWM.1 | NEK3 | SKNIFLTQNGK | Activation Loop | -12.44583296 | 1 | uM |
| Ibrutinib | BCWM.1 | NEK4 | DLKTQNVFLTR | Lys2 | 9.27527989 | 1 | uM |
| Ibrutinib | BCWM.1 | NEK6,NEK7 | DIKPANVFITATGVVK | Lys2 | -2.498961176 | 1 | uM |
| Ibrutinib | BCWM.1 | NEK7 | AACLLDGVPVALKK | Lys1 | 11.72564622 | 1 | uM |
| Ibrutinib | BCWM.1 | NEK8 | DLKTQNILLDK | Lys2 | -15.33883097 | 1 | uM |