Ibrutinib KiNativ -- single dose experiment - Dataset (ID:20214)
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| Small Molecule | Cell Line | Protein | Sequence | Labeling Site | % Inhibition | Assay compound conc | Conc unit |
|---|---|---|---|---|---|---|---|
| Ibrutinib | BCWM.1 | JAK1_domain2 | IGDFGLTKAIETDKEYYTVK | Activation Loop | 24.89996943 | 1 | uM |
| Ibrutinib | BCWM.1 | JAK3 domain2 | IADFGLAKLLPLDKDYYVVR | Activation Loop | 35.44676685 | 1 | uM |
| Ibrutinib | BCWM.1 | JNK1,JNK2,JNK3 | DLKPSNIVVK | Lys2 | 12.48066089 | 1 | uM |
| Ibrutinib | BCWM.1 | KHS1 | NVHTGELAAVKIIK | Lys1 | 2.575668332 | 1 | uM |
| Ibrutinib | BCWM.1 | KSR1,KSR2 | SKNVFYDNGK | Activation Loop | 10.93063105 | 1 | uM |
| Ibrutinib | BCWM.1 | LATS1 | ALYATKTLR | Lys1 | 2.515282486 | 1 | uM |
| Ibrutinib | BCWM.1 | LATS2 | DIKPDNILIDLDGHIK | Lys2 | -3.257610869 | 1 | uM |
| Ibrutinib | BCWM.1 | LKB1 | DIKPGNLLLTTGGTLK | Lys2 | -0.513579966 | 1 | uM |
| Ibrutinib | BCWM.1 | LOK | DLKAGNVLMTLEGDIR | Lys2 | -27.14574463 | 1 | uM |
| Ibrutinib | BCWM.1 | LRRK2 | DLKPHNVLLFTLYPNAAIIAK | Lys2 | -4.659814674 | 1 | uM |
| Ibrutinib | BCWM.1 | LYN | VAVKTLKPGTMSVQAFLEEANLMK | Lys1 | 5.025210437 | 1 | uM |
| Ibrutinib | BCWM.1 | MAP2K1 | IMHRDVKPSNILVNSR | Lys2 | -30.4885235 | 1 | uM |
| Ibrutinib | BCWM.1 | MAP2K1,MAP2K2 | DVKPSNILVNSR | Lys2 | 13.06119726 | 1 | uM |
| Ibrutinib | BCWM.1 | MAP2K3 | DVKPSNVLINK | Lys2 | 9.051933111 | 1 | uM |
| Ibrutinib | BCWM.1 | MAP2K4 | DIKPSNILLDR | Lys2 | 7.654401095 | 1 | uM |
| Ibrutinib | BCWM.1 | MAP2K5 | DVKPSNMLVNTR | Lys2 | 2.336577961 | 1 | uM |
| Ibrutinib | BCWM.1 | MAP2K6 | DVKPSNVLINALGQVK | Lys2 | 11.91336668 | 1 | uM |
| Ibrutinib | BCWM.1 | MP2K7 | DVKPSNILLDER | Lys2 | 44.63707193 | 1 | uM |
| Ibrutinib | BCWM.1 | MAP3K1 | DVKGANLLIDSTGQR | Lys2 | 27.25870816 | 1 | uM |
| Ibrutinib | BCWM.1 | M3K2 | ELAVKQVQFDPDSPETSKEVNALECEIQLLK | Lys1 | -20.1709184 | 1 | uM |
| Ibrutinib | BCWM.1 | M3K2,MAP3K3 | DIKGANILR | Lys2 | -12.68497138 | 1 | uM |
| Ibrutinib | BCWM.1 | MAP3K3 | ELASKQVQFDPDSPETSKEVSALECEIQLLK | Lys1 | 3.568452729 | 1 | uM |
| Ibrutinib | BCWM.1 | MAP3K4 | DIKGANIFLTSSGLIK | Lys2 | -6.705973934 | 1 | uM |
| Ibrutinib | BCWM.1 | MAP3K5 | DIKGDNVLINTYSGVLK | Lys2 | 9.414089745 | 1 | uM |
| Ibrutinib | BCWM.1 | MARK2,MARK3 | DLKAENLLLDADMNIK | Lys2 | -14.37963599 | 1 | uM |