Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
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| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| Ixabepilone | ZR75B | -4.4045 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | 5.6203 |
| LBH589 | MCF7 | -4.4776 | 0.9871 | -6.8476 | -6.8292 | -7.1240 | 1.5240 | 0.0316 | 0.0318 | 5.3056 |
| LBH589 | SK-BR-3 | -4.4776 | 0.9866 | -7.1326 | -7.1301 | -7.2387 | 3.8280 | 0.0109 | 0.0109 | 4.8858 |
| LBH589 | MDA-MB-231 | -4.4776 | 0.9633 | -6.6436 | -6.6333 | -6.6787 | 2.8870 | 0.0321 | 0.0321 | 5.6375 |
| LBH589 | AU565 | -4.4776 | 0.9834 | -6.9676 | -6.9639 | -7.0587 | 2.7590 | 0.0109 | 0.0109 | 4.9219 |
| LBH589 | BT-20 | -4.4776 | 0.9522 | -6.3286 | -6.2631 | -6.4673 | 2.0190 | 0.1314 | 0.1316 | 6.2071 |
| LBH589 | BT-474 | -4.4776 | 0.9663 | -6.9556 | -6.9454 | -7.4121 | 1.4660 | 0.0172 | 0.0175 | 4.9235 |
| LBH589 | BT-483 | -4.4776 | 0.9627 | -6.6211 | -6.4579 | -7.1208 | 1.1575 | 0.1738 | 0.1769 | 5.9825 |
| LBH589 | BT-549 | -4.4776 | 0.9794 | -6.8416 | -6.8369 | -6.9428 | 1.1250 | 0.0057 | 0.0079 | 5.2279 |
| LBH589 | CAMA-1 | -4.4776 | 0.9728 | -7.2096 | -7.1866 | -7.3742 | 2.5695 | 0.0663 | 0.0663 | 4.7648 |
| LBH589 | HCC1143 | -4.4776 | 0.9211 | -7.0096 | -6.9462 | -7.1509 | 1.3210 | 0.0872 | 0.0876 | 5.1496 |
| LBH589 | HCC1395 | -4.4776 | 0.9488 | -6.3046 | -6.2351 | -6.5794 | 1.5770 | 0.1127 | 0.1172 | 6.1936 |
| LBH589 | HCC1419 | -4.4776 | 0.9564 | -6.5756 | -6.5755 | -7.1834 | 1.2380 | 0.0000 | 0.0025 | 5.2243 |
| LBH589 | HCC1428 | -4.4776 | 0.9692 | -6.8721 | -6.8673 | -7.0469 | 3.0800 | 0.0152 | 0.0152 | 5.0165 |
| LBH589 | HCC1569 | -4.4776 | 0.9779 | -6.5516 | -6.5240 | -6.8220 | 1.5305 | 0.0449 | 0.0475 | 5.7844 |
| LBH589 | HCC1806 | -4.4776 | 0.9872 | -6.7156 | -6.7160 | -6.8511 | 1.4270 | 0.0000 | 0.0006 | 5.2350 |
| LBH589 | HCC1937 | -4.4776 | 0.9558 | -6.4966 | -6.4173 | -6.7418 | 1.3670 | 0.1110 | 0.1125 | 6.0029 |
| LBH589 | HCC1954 | -4.4776 | 0.9765 | -6.2816 | -6.2607 | -6.4678 | 1.2910 | 0.0303 | 0.0348 | 6.0080 |
| LBH589 | HCC202 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| LBH589 | HCC38 | -4.4776 | 0.9825 | -7.3526 | -7.3521 | -7.4968 | 1.6360 | 0.0013 | 0.0014 | 4.2907 |
| LBH589 | HCC70 | -4.4776 | 0.9907 | -6.9851 | -6.9812 | -7.1521 | 2.4045 | 0.0102 | 0.0102 | 4.9699 |
| LBH589 | Hs 578T | -4.4776 | 0.9771 | -6.4656 | -6.4606 | -6.5229 | 2.8990 | 0.0150 | 0.0150 | 5.7470 |
| LBH589 | MB 157 | -4.4776 | 0.9963 | -7.0016 | -6.9966 | -7.1499 | 1.2640 | 0.0077 | 0.0083 | 4.9865 |
| LBH589 | MDA-MB-134-VI | -4.4776 | 0.9583 | -6.8901 | -6.6939 | -7.1038 | 1.6615 | 0.2638 | 0.2638 | 6.0309 |
| LBH589 | MDA-MB-157 | -4.4776 | 0.9879 | -6.9976 | -6.9973 | -7.3133 | 1.0900 | 0.0000 | 0.0018 | 4.9496 |