Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
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| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| GSK1838705A | HCC1806 | -4.1759 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | 8.5117 |
| GSK1838705A | HCC1937 | -4.1759 | 0.8073 | -5.2979 | -5.2364 | -5.3389 | 3.9960 | 0.2160 | 0.2160 | 8.1699 |
| GSK1838705A | HCC1954 | -4.1759 | 0.8775 | -4.8884 | -4.8884 | -5.0550 | 1.9875 | 0.0000 | 0.0364 | 7.3224 |
| GSK1838705A | HCC202 | -4.1759 | 0.9280 | -4.8555 | -4.8555 | -5.1129 | 2.8080 | 0.0000 | 0.0122 | 7.6197 |
| GSK1838705A | HCC38 | -4.1759 | 0.9258 | -5.0423 | -5.0415 | -5.1211 | 2.7700 | 0.0026 | 0.0065 | 7.0266 |
| GSK1838705A | HCC70 | -4.1759 | 0.9405 | -5.1779 | -5.1734 | -5.3484 | 2.8970 | 0.0141 | 0.0154 | 6.7443 |
| GSK1838705A | Hs 578T | -4.1759 | 0.7577 | -5.0824 | -5.0752 | -5.1186 | 3.9910 | 0.0866 | 0.0875 | 8.2059 |
| GSK1838705A | MB 157 | -4.1759 | 0.9174 | -5.0031 | -5.0030 | -5.1017 | 0.8689 | 0.0000 | 0.1605 | 6.9197 |
| GSK1838705A | MDA-MB-134-VI | -4.1759 | 0.9460 | -4.9248 | -4.9248 | -5.2286 | 1.7830 | 0.0000 | 0.0445 | 7.0493 |
| GSK1838705A | MDA-MB-157 | -4.1759 | 0.8740 | -4.8082 | -4.8081 | -5.1173 | 1.5740 | 0.0000 | 0.1329 | 7.5107 |
| GSK1838705A | MDA-MB-175-VII | -4.1759 | 0.9697 | -5.2699 | -5.2661 | -5.4282 | 3.2410 | 0.0166 | 0.0181 | 7.2558 |
| GSK1838705A | MDA-MB-361 | -4.1759 | 0.9461 | -4.7118 | -4.7118 | -4.8827 | 2.7925 | 0.0000 | 0.0312 | 7.7912 |
| GSK1838705A | MDA-MB-436 | -4.1759 | 0.9183 | -5.2789 | -5.2763 | -5.3773 | 2.3310 | 0.0068 | 0.0095 | 6.4980 |
| GSK1838705A | MDA-MB-453 | -4.1759 | 0.8830 | -5.2994 | -5.2354 | -5.3617 | 3.9990 | 0.1505 | 0.1505 | 7.4471 |
| GSK1838705A | MDA-MB-468 | -4.1759 | 0.9230 | -5.3839 | -5.2809 | -5.3703 | 1.6680 | 0.0595 | 0.0636 | 7.1758 |
| GSK1838705A | T47D | -4.1759 | 0.9222 | -4.7998 | -4.7998 | -5.0548 | 1.6920 | 0.0000 | 0.0831 | 7.3917 |
| GSK1838705A | UACC-812 | -4.1759 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | 7.1410 |
| GSK1838705A | UACC-893 | -4.1759 | 0.8349 | -5.4599 | -5.3578 | -5.5630 | 4.0000 | 0.3047 | 0.3047 | 7.8857 |
| GSK1838705A | ZR-75-1 | -4.1759 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | 7.6415 |
| GSK1838705A | 184B5 | -4.1759 | 0.9795 | -6.1249 | -5.9020 | -6.3796 | 0.7167 | 0.1540 | 0.1866 | 6.1329 |
| GSK1838705A | HCC1187 | -4.1759 | 0.9431 | -5.4009 | -5.4007 | -5.6091 | 1.6210 | 0.0000 | 0.0257 | 6.6319 |
| GSK1838705A | MCF 10A | -4.1759 | 0.9671 | -5.3889 | -5.3889 | -5.5186 | 0.9268 | 0.0208 | 0.0369 | 6.6135 |
| GSK1838705A | MCF 10F | -4.1759 | 0.9102 | -6.1259 | -6.0139 | -6.2804 | 2.7915 | 0.2454 | 0.2465 | 6.7563 |
| GSK1838705A | SUM1315MO2 | -4.1759 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | 7.7033 |
| GSK1838705A | SUM149PT | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |