Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
Download: Excel (XLSX), Comma-separated (CSV)
| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| Ibandronate | CAMA-1 | -2.8239 | 0.9353 | -3.6538 | -3.6125 | -3.8697 | 2.7190 | 0.1001 | 0.1246 | 7.4016 |
| Ibandronate | HCC1143 | -2.8239 | 0.9761 | -4.1079 | -4.0126 | -4.4078 | 0.7501 | 0.0759 | 0.1666 | 6.8265 |
| Ibandronate | HCC1395 | -2.8239 | 0.8383 | -4.4334 | -3.7882 | -4.9995 | 0.4618 | 0.2470 | 0.3637 | 6.6754 |
| Ibandronate | HCC1419 | -2.8239 | 0.8810 | -4.6419 | -3.5473 | -5.1499 | 0.7265 | 0.4199 | 0.4464 | 7.1921 |
| Ibandronate | HCC1428 | -2.8239 | 0.9518 | -3.7368 | -3.1782 | -3.9275 | 1.5325 | 0.4179 | 0.4537 | 7.9304 |
| Ibandronate | HCC1569 | -2.8239 | 0.9745 | -4.1779 | -3.8755 | -4.2352 | 1.8030 | 0.3410 | 0.3437 | 7.3386 |
| Ibandronate | HCC1806 | -2.8239 | 0.9317 | -4.4029 | -4.3485 | -4.5453 | 1.0880 | 0.0638 | 0.0814 | 5.9744 |
| Ibandronate | HCC1937 | -2.8239 | 0.9383 | -4.5169 | -4.0625 | -4.5716 | 1.1350 | 0.3475 | 0.3552 | 7.1787 |
| Ibandronate | HCC1954 | -2.8239 | 0.9365 | -4.2519 | -4.1608 | -4.2576 | 3.9990 | 0.2831 | 0.2831 | 7.3730 |
| Ibandronate | HCC202 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| Ibandronate | HCC38 | -2.8239 | 0.9586 | -4.2074 | -4.1813 | -4.3368 | 2.2955 | 0.0580 | 0.0703 | 6.4989 |
| Ibandronate | HCC70 | -2.8239 | 0.9039 | -4.1924 | -3.8216 | -4.1977 | 2.6475 | 0.4164 | 0.4207 | 7.4528 |
| Ibandronate | Hs 578T | -2.8239 | 0.9646 | -4.9269 | -4.8945 | -5.0708 | 1.1060 | 0.0391 | 0.0436 | 5.5086 |
| Ibandronate | MB 157 | -2.8239 | 0.9724 | -3.8709 | -3.8713 | -4.0221 | 1.2260 | 0.0000 | 0.0494 | 7.0943 |
| Ibandronate | MDA-MB-134-VI | -2.8239 | 0.9266 | -3.9059 | -3.6032 | -4.2035 | 1.2850 | 0.2899 | 0.3184 | 7.5074 |
| Ibandronate | MDA-MB-157 | -2.8239 | 0.9687 | -4.1909 | -4.1744 | -4.3860 | 1.8410 | 0.0333 | 0.0362 | 6.8707 |
| Ibandronate | MDA-MB-175-VII | -2.8239 | 0.9357 | -4.0439 | -3.9218 | -4.4429 | 1.4740 | 0.1617 | 0.1749 | 6.7555 |
| Ibandronate | MDA-MB-361 | -2.8239 | 0.9746 | -4.4249 | -4.3147 | -4.8071 | 1.6940 | 0.1749 | 0.1765 | 6.8192 |
| Ibandronate | MDA-MB-436 | -2.8239 | 0.9274 | -4.1389 | -4.1390 | -4.7604 | 0.8648 | 0.0000 | 0.0679 | 6.7064 |
| Ibandronate | MDA-MB-453 | -2.8239 | 0.9521 | -3.8859 | -3.8591 | -4.0394 | 2.3780 | 0.0682 | 0.0710 | 6.9102 |
| Ibandronate | MDA-MB-468 | -2.8239 | 0.9442 | -3.9789 | -3.9556 | -4.0749 | 1.7430 | 0.0453 | 0.0544 | 6.7359 |
| Ibandronate | T47D | -2.8239 | 0.9567 | -4.5789 | -4.2635 | -4.5232 | 1.8680 | 0.3715 | 0.3718 | 7.0294 |
| Ibandronate | UACC-812 | -2.8239 | 0.9091 | -3.7606 | -3.6356 | -3.9337 | 2.5590 | 0.2801 | 0.2813 | 7.3571 |
| Ibandronate | UACC-893 | -2.8239 | 0.9399 | -3.8449 | -3.4770 | -4.4865 | 0.9299 | 0.2728 | 0.3462 | 7.4112 |
| Ibandronate | ZR-75-1 | -2.8239 | 0.9588 | -4.0979 | -3.6865 | -4.1988 | 1.5030 | 0.3796 | 0.3871 | 7.4547 |