Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
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| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| Etoposide | MDA-MB-157 | -3.4776 | 0.9397 | -5.2866 | -5.2864 | -6.0724 | 0.5334 | 0.0000 | 0.0978 | 5.7275 |
| Etoposide | MDA-MB-175-VII | -3.4776 | 0.8153 | -4.4210 | -3.4776 | -4.1525 | 0.7104 | 0.6756 | 0.7327 | 8.4739 |
| Etoposide | MDA-MB-361 | -3.4776 | 0.9650 | -4.6326 | -4.4807 | -4.8662 | 1.9500 | 0.2340 | 0.2404 | 7.3917 |
| Etoposide | MDA-MB-436 | -3.4776 | 0.9654 | -5.8966 | -5.5006 | -5.9347 | 0.8570 | 0.2711 | 0.2772 | 6.1782 |
| Etoposide | MDA-MB-453 | -3.4776 | 0.9304 | -4.9746 | -4.6718 | -5.3821 | 0.5025 | 0.1488 | 0.2852 | 6.4842 |
| Etoposide | MDA-MB-468 | -3.4776 | 0.9768 | -5.6971 | -5.6789 | -5.8319 | 1.4460 | 0.0292 | 0.0300 | 5.4062 |
| Etoposide | T47D | -3.4776 | 0.9735 | -5.8781 | -5.5475 | -6.0343 | 1.0353 | 0.2565 | 0.2611 | 6.0001 |
| Etoposide | UACC-812 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| Etoposide | UACC-893 | -3.4776 | 0.9771 | -4.2249 | -4.1924 | -4.4386 | 2.2390 | 0.0773 | 0.0965 | 7.3527 |
| Etoposide | ZR-75-1 | -3.4776 | 0.9632 | -5.1636 | -4.6227 | -5.6989 | 0.6001 | 0.2631 | 0.3291 | 6.8258 |
| Etoposide | 184B5 | -3.4776 | 0.9633 | -4.5678 | -4.4273 | -5.0951 | 0.5723 | 0.0910 | 0.2747 | 6.8156 |
| Etoposide | HCC1187 | -3.4776 | 0.9482 | -5.6686 | -5.6686 | -6.2307 | 0.8275 | 0.0000 | 0.0178 | 5.3989 |
| Etoposide | MCF 10A | -3.4776 | 0.9356 | -5.3466 | -5.3469 | -5.4148 | 0.4964 | 0.0145 | 0.1056 | 5.7838 |
| Etoposide | MCF 10F | -3.4776 | 0.9115 | -6.1406 | -5.0331 | -6.1903 | 0.4879 | 0.3560 | 0.3868 | 6.2122 |
| Etoposide | SUM1315MO2 | -3.4776 | 0.9483 | -5.6381 | -5.3511 | -6.5663 | 0.5097 | 0.1409 | 0.2051 | 5.9895 |
| Etoposide | SUM149PT | -3.4776 | 0.9480 | -5.2386 | -5.2383 | -5.5955 | 0.5509 | 0.0000 | 0.0968 | 5.9119 |
| Etoposide | SUM159PT | -3.4776 | 0.9681 | -6.0866 | -6.0595 | -6.1480 | 1.0690 | 0.0326 | 0.0341 | 5.0925 |
| Etoposide | SUM185PE | -3.4776 | 0.8862 | -4.7696 | -3.5564 | -5.2826 | 0.5540 | 0.3936 | 0.4915 | 7.6197 |
| Etoposide | SUM225CWN | -3.4776 | 0.8914 | -4.9861 | -4.6040 | -4.9845 | 3.5845 | 0.4711 | 0.4711 | 7.7229 |
| Etoposide | SUM229PE | -3.4776 | 0.9864 | -5.7671 | -5.7172 | -6.0821 | 0.9411 | 0.0553 | 0.0659 | 5.3267 |
| Etoposide | SUM52PE | -3.4776 | 0.9809 | -5.4316 | -5.2850 | -5.6157 | 1.3060 | 0.1785 | 0.1808 | 6.2867 |
| Etoposide | 184A1 | -3.4776 | 0.9515 | -4.5937 | -4.5938 | -5.0898 | 0.7937 | 0.0000 | 0.1174 | 6.7842 |
| Etoposide | MCF12A | -3.4776 | 0.9782 | -6.1316 | -6.0783 | -6.4905 | 0.4147 | 0.0249 | 0.0970 | 4.7863 |
| Etoposide | MX1 | -3.4776 | 0.9631 | -5.3256 | -5.3256 | -6.3576 | 0.5445 | 0.0000 | 0.0897 | 5.6932 |
| Etoposide | T47DKBLUC | -3.4776 | 0.9466 | -5.7246 | -4.2055 | -5.8257 | 1.1160 | 0.4899 | 0.4915 | 7.2533 |